A system and method for identifying a post cecum position of an ingestible, phototherapeutic capsule traveling through a gastrointestinal (GI) tract to prevent intestinal blockage and facilitating deployment of additional phototherapeutic capsules in accordance with patient needs. The system employs an ex-vitro beacon in wireless communication with the capsule. The ex-vitro beacon is deployed in the vicinity of the McBurney's point to direct a beacon signal toward the cecum to identify capsule passage into the large intestine less prone to blockage.

Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.

Provided is a skin care device including a head part brought into contact with skin of a user, a battery configured to supply power for operation of the head part, a body part having a fastening portion provided at one end to which the head part is fastened and provided with the battery therein, and a cap assembly detachably attached to one end of the body part and forming an accommodation space configured to accommodate the head part, wherein the cap assembly includes a sterilization module disposed to irradiate ultraviolet light toward the head part when the cap assembly accommodates the head part.

A device and method for disinfecting and/or enhancing healing of a wound or surgical site facilitates placing a light-emitting device with a frame having a central void, the central void adapted to surround the wound or surgical site; an illumination source disposed on the frame for directing safe, therapeutic light centrally towards the underlying wound or surgical site; and the transparent central void enabling visualization and clinical monitoring of the underlying wound or surgical site.

A method of reducing the risk of ventilator-associated pneumonia by decontaminating the oropharynx using a safe, antimicrobial light-emitting device.

Methods and apparatus for the inactivation of infectious agents in, on or around a catheter residing in a patient's body cavity. The method comprises a coupling adapter for facilitating the transmission of non-ultraviolet sterilizing electromagnetic radiation (EMR) substantially axially along an optical element into the catheter body. Through delivery of the sterilizing EMR to particular areas of highest infection, the present disclosure is able to inactivate the major sources of infection in catheters.

Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.

A portable hair removal device (10), comprising a head portion (30), and a housing (20) connected to one end of the head portion (30). An emitter capable of emitting light is provided in the housing (20), and the light emitted by the emitter passes through the head portion (30) and then acts on the skin for hair removal. The head portion (30) is provided with at least a phototherapy lamp (32), and light emitted by the phototherapy lamp (32) acts on the skin through the head (30) and takes care of the skin. The portable hair removal device (10) has rich functions and a good skin care effect.

A device for eradicating at least one pathogen in a nasal passage of a human or animal may include a housing configured to be inserted into the nasal passage, at least one radiation source, configured to emit radiation, coupled to the housing such that at least a portion of a radiation emitting surface, upon insertion of the housing into the nasal passage, faces at least a portion of nasal lining of the nasal passage, and an electrical circuit carried by the housing and electrically connected to the at least one radiation source, the electrical circuit including at least one circuit component for controlling the at least one radiation source to emit the radiation to irradiate the nasal passage, the emitted radiation having a frequency or range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated.

A light irradiation device includes a first light source emitting first light in a visible wavelength band and a second light source emitting second light, in which at least part of a wavelength band is different from a wavelength band of the first light source and which catalyzes synthesis of a functional substance in a target to which light is applied. The second light includes light in a wavelength band of ultraviolet B.