A therapy system includes a therapy output device that includes light sources and a controller. The light sources are configured to output electromagnetic radiation at different peak wavelengths. The controller is configured to operate the light sources to output the electromagnetic radiation to differ between a first therapy program and second therapy program by at least one of peak wavelengths, irradiance of one or more of the peak wavelengths, or energy density of the one or more peak wavelengths.

Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

A system includes a frame, and an image processing unit, a laser unit and an adjusting unit that are mounted on the frame. The image processing unit includes an image capturing device and a processor. The image capturing device captures an image of a body part. The processor generates a control signal based on the image. The laser unit includes a light source and an optical component. The light source emits a laser beam. The adjusting unit is connected to the processor, and interconnects the optical component and the frame. The adjusting unit receives the control signal, and orients, based on the control signal, the optical component to direct the laser beam to acupuncture points on the body part individually.

Provided is a swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.

A system, for transcutaneous photodynamic therapy in an organ or organ segment of an organic body, includes a plurality of light applicators (9), a supply unit (23) and a placement template (39) placeable relative to the organic body for defined orientation of the light applicators. The light applicators include a needle-shaped insertion portion (15) for transcutaneous piercing along a piercing axis (E), a light-emitting applicator tip (19) at the distal end (13) of the insertion portion, and a fixing point (43) at a proximal distance d from the applicator tip. The placement template defines a plurality of fixing point receptacles (51) for fixing the light applicators with a defined fixing point and includes a first and second template parts (71, 75) defining first and second subsets (73, 77) of fixing point receptacles. The first template part is guidingly displaceable relative to the second template part along the piercing axis.

A system, for transcutaneous photodynamic therapy in an organ or organ segment of an organic body, includes a plurality of light applicators, a supply unit and a placement template placeable relative to the organic body for defined orientation of the light applicators. The light applicators include a needle-shaped insertion portion for transcutaneous piercing along a piercing axis, a light-emitting applicator tip at the distal end of the insertion portion, and a fixing point at a proximal distance from the applicator tip. The placement template defines fixing point receptacles for fixing the light applicators with a defined fixing point wherein the receptacles are arranged in accordance with a three-dimensional fixing point grid structure, that corresponds to a virtual organ-specific target point grid structure for the light-emitting applicator tips in the organ that is arranged parallel-displaced relative to the target point grid structure by the distance d along the piercing axis.

A medical wound healing accelerator having a body that is removably attached on a fixing pin, of an external fixator for fractures, that is insertable into a bone through skin is provided. The device can further include a plurality of light source units arranged on one surface of the body to emit light and provide a beneficial effect to the wound, and a controller electrically connected to the light source units. An osteomyelitis treatment device having an insert that is insertable into an osteomyelitis part in a human body, and a plurality of light-emitting members provided to the insert to emit light is also provided. The plurality of light-emitting members can be spaced apart from each other, and a part of the insert can be cut or bent to correspond to the shape of the osteomyelitis part.

An apparatus for tissue regeneration is provided. The apparatus comprises means for generating at least one laser pulse comprising a wavelength; and means for directing the at least one laser pulse onto a tissue surface of a human or animal body, wherein the means for generating comprises control means to ensure that a sum of the pulse energies of the at least one laser pulse is selected so that the corresponding fluence on the tissue surface heats the tissue surface up to a maximal temperature T.sub.max between 70° C. and a tissue boiling temperature T.sub.b. Further, the means for generating of the apparatus are adapted so that a delivery time t.sub.ed of the at least one laser pulse (during which the second half of the pulse energy is delivered) is sufficiently short so that, given the wavelength and thus a corresponding penetration depth δ of the at least one laser pulse, a thermal exposure time t.sub.exp of the tissue surface is shorter than 900 microseconds. Here, the thermal exposure time t.sub.exp of the tissue surface is defined as a time interval in which the temperature of the tissue surface is above T.sub.o+(T.sub.max−T.sub.o)/2, wherein T.sub.o defines the initial temperature of the tissue surface, before the laser pulse arrives.

Provided a method of sterilization by ultraviolet irradiation whereby effects on the human body can be mitigated and an odor that arises after ultraviolet irradiation can be controlled. The sterilization method includes: a step (a) of irradiating a skin of a hand or arm with ultraviolet having a wavelength of 200 nm or more and 230 nm or less; and a step (b) of applying a topical skin preparation, cosmetic, or aqueous solution containing at least one amino acid or amino acid derivative selected from an amino acid group A to a region of the skin irradiated with the ultraviolet. The amino acid group A includes valine, leucine, isoleucine, glutamic acid, arginine, serine, aspartic acid, proline, and glycine.