A radiation detection apparatus capable of monitoring a radiation dose during incidence, includes an obtaining unit configured to obtain a setting of an imaging range including a plurality of parts of an object and a setting of at least one target part that is a target of automatic exposure control in the plurality of parts, a specifying unit configured to specify, based on radiation transmission amounts set for the plurality of parts and radiation doses monitored in a plurality of detection regions of the radiation detection apparatus, at least one target detection region located at a position where radiation transmitted through the at least one target part enters from the plurality of detection regions, and an output unit configured to output the radiation dose monitored in the at least one target detection region.

The present invention relates a detector (11) for detecting megavoltage X-ray radiation (3), comprising a scintillator (2) including a plurality of heavy scintillating fibers (13) for emitting scintillation photons in response to incident megavoltage X-ray radiation (3), a support structure (15) for supporting said plurality of heavy scintillating fibers (13) and holding them in place; and a photodetector (17) for detecting the spatial intensity distribution of the emitted scintillation photons. The present invention further relates to an apparatus (35) for radiation therapy comprising a particle accelerator (37) and a detector (11) for detecting megavoltage radiation. Still further, the present invention relates to methods for detecting X-ray radiation and for radiation therapy.

Systems and methods can include obtaining computerized physician intent data representing an initial patient care plan; creating a computerized workflow to include a course of multiple radiation therapy sessions; performing instructions on the oncology computer system to generate control parameters for a radiation therapy apparatus to provide the radiation treatment in accordance with the workflow during the course of sessions; obtaining computerized treatment data after initiating the course of sessions; processing the computerized treatment data, using the processor circuit, to determine an indication of delivery or effect of the radiation treatment during the course of sessions based on the initial patient care plan relative to the workflow; using the indication of delivery or effect of the radiation treatment to adapt the patient care plan; and managing the workflow for the patient using the adapted patient care plan as the patient proceeds through a course of sessions.

A proton radiography system includes a source of a proton beam at nonrelativistic energy, directed on a beam path to an object to be imaged; one or more time-of-flight (TOF) detectors arranged on the beam path to detect incidence of beam protons and generate output signals indicative thereof with a time resolution substantially less than a time of flight of the protons; and a data acquisition and analysis subsystem coupled to the TOF detectors to receive the respective output signals and (1) calculate TOF values for respective bunches of one or more protons, (2) convert the TOF values to proton velocity values and proton energy values, and (3) use the proton energy values to calculate a corresponding value for a physical property of the object along the beam path, and incorporate the value into elements of a radiographic image of the object stored or displayed in the system.

An apparatus for determining a contour of a treatment region in a patient includes a computer processor to receive input regarding a contour of at least one organ-at-risk (OAR) adjacent to the treatment region; receive input regarding an initial contour of the treatment region; predict a radiation toxicity to the at least one OAR based on the contour of the at least one OAR, the initial contour of the treatment region, and a radiation treatment regimen; determine whether the predicted radiation toxicity exceeds a threshold; and determine a contour of the treatment region by iteratively modifying the initial contour of the treatment region, and any subsequent modified contours of the treatment region, until a stopping condition is satisfied. The stopping condition can be a preselected number of iterations or that the predicted radiation toxicity using the contour in place of the initial contour is first calculated is below said threshold.

Particle radiation therapy and planning utilizing magnetic resonance imaging (MRI) data. Radiation therapy prescription information and patient MRI data can be received and a radiation therapy treatment plan can be determined for use with a particle beam. The treatment plan can utilize the radiation therapy prescription information and the patient MRI data to account for interaction properties of soft tissues in the patient through which the particle beam passes. Patient MRI data may be received from a magnetic resonance imaging system integrated with the particle radiation therapy system. MRI data acquired during treatment may also be utilized to modify or optimize the particle radiation therapy treatment.

A radiation treatment system is described, including a linear accelerator (LINAC), having a housing, to emit a treatment beam to a target location and a Cerenkov emission detector, coupled to the housing of the LINAC, to capture a set of images of optical Cerenkov emission generated at the target location by charged particles of the treatment beam. A method is described including emitting the treatment beam from the LINAC to the target location and capturing, using the Cerenkov emission detector coupled to the LINAC, the set of images of optical Cerenkov emission generated at the target location by the treatment beam.

A system and method for image-guided radiotherapy are provided. The system may include a treatment assembly and an imaging assembly. The treatment assembly may include a first radiation source configured to deliver a treatment beam. The treatment assembly may have a treatment region relating to an object. The imaging assembly may include a second radiation source and a radiation detector. The second radiation source may be configured to deliver an imaging beam, and the radiation detector may be configured to detect at least a portion of the imaging beam. The imaging assembly may have an imaging region relating to the object. The first radiation source may be rotatable in a first plane, and the second radiation source may be rotatable in a second plane different from the first plane, such that the treatment region and the imaging region at least partially overlap.

The present invention describes a membrane mask for immobilization of a region of interest during radiation therapy. The mask comprises at least one material forming a matrix, and at least one radiation-sensitive material integrated as micro- or nano-sized material elements in or onto the matrix. The radiation-sensitive material advantageously provides the possibility of using the mask for performing dosimetry. Use of the mask and a method for performing dosimetry also are described.

A method of radiation therapy comprises, while a gantry of a radiation therapy system rotates continuously in a first direction through a treatment arc from a first treatment delivery position to a second treatment delivery position, causing an imaging X-ray source mounted on the gantry to direct X-rays through a target volume and receiving a set of X-ray projection images from an X-ray imager mounted on the gantry; determining a current location of the target volume based on the set of X-ray projection images; and while the gantry to continues to rotate to the second treatment delivery position, initiating delivery of a treatment beam of a treatment-delivering X-ray source mounted on the gantry to the target volume, and continuing to cause the gantry to rotate in the first direction from the second treatment delivery position to a third treatment delivery position.