A method of delivering a radioactive liquid includes, performing an initialization, including; extracting at least a first amount of a radioactive liquid from a source of radioactive liquid, measuring a radioactivity level for the first amount of radioactive liquid, and performing a calibration phase. The calibration phase includes, extracting a second amount of radioactive liquid from the source of radioactive liquid wherein the second amount is calculated based on the radioactivity level of the first amount to provide a total dose of radioactive liquid having a predetermined radioactivity level, and delivering the total dose and performing at least one more calibration and delivery phases.

Some embodiments are directed to an image director of a patient monitoring system to obtain calibration images of a calibration sheet or other calibration object at various orientations and locations. The images are then stored and processed to calculate camera parameters defining the location and orientation of the image detector and identifying internal characteristics of the image detector, and the information are stored. The patient monitoring system can be re-calibrated by using the image detector to obtain an additional image of a calibration sheet or calibration object. The additional image and the stored camera parameters are then used to detect any apparent change in the internal characteristics of the image detector (10) (S6-4).

A system and method for recording in real-time the duration, position, and energy of ion beams as delivered by a proton or heavy ion cancer treatment system for the purpose of calibrating the radiological system and verifying the treatment plans for various lesions. The energy of the ion beam is calculated from the beam ion depth penetration through a phantom as recorded on a two-dimensional scintillator surface which is viewed by a sensitive visible-light camera mounted in a darkened enclosure. The energy of the beam is degraded by a novel multi-step dual-slope chevron wedge phantom which creates, at a minimum, two bright spots in the camera's field of view. The distance between the centers of these two spots along with the dimensions and density of the multi-step dual-slope chevron wedge are used to calculate the Bragg Peak penetration depth of the ion beam. A computer connected to the camera measures the location and intensity of these spots during treatment delivery and archives the original beam image, spot parameters, timing, and computed beam energies to memory. Software algorithms reconstruct a mathematical description of each treatment beam. The operator can then determine discrepancies between the measured dosimetric pattern and the intended treatment or calibration pattern.

A particle beam detector system can comprise a particle beam generator, a particle beam fluence and position detector array based on Micromegas technology, and data readout electronics coupled to the position detector array. The particle beam fluence and position detector array can comprise a sealed, gas-filled, ionizing radiation detector chamber. A printed circuit board (PCB) can be disposed within the ionizing radiation detector chamber, the PCB comprising a multi-layer array arrangement of interconnected conductive sensor pads comprising three planar coordinate grids, X, Y, and ST (stereo) situated on separate layers of the PCB. The multi-layer array arrangement of interconnected conductive sensor pads can comprise a first footprint. A dielectric lattice structure can be disposed over the PCB and the multi-layer array arrangement of sensors. A conductive mesh structure can comprise a second footprint disposed over the dielectric lattice structure and extending over an entire area of the first footprint.

A detector for measuring scanning ion beams in radiation therapy sequentially includes a first high voltage electrode, a first spacing member, and a segmented electrode. The first spacing member is connected to the first high voltage electrode and the segmented electrode to form a first ionization cavity. The first ionization cavity is formed with a plurality of first reading electrodes and a plurality of second reading electrodes therein. A second spacing member and a second high voltage electrode are further sequentially disposed. The second spacing member is connected to the second high voltage electrode and the segmented electrode to form a second ionization cavity. The first reading electrodes and the second reading electrodes are respectively formed in the first ionization cavity and the second ionization cavity. With the first reading electrodes and the second reading electrodes in different directions, highly accurate space resolution, space dosage and scanning speed are achieved.

Systems and methods can include obtaining computerized physician intent data representing an initial patient care plan; creating a computerized workflow to include a course of multiple radiation therapy sessions; performing instructions on the oncology computer system to generate control parameters for a radiation therapy apparatus to provide the radiation treatment in accordance with the workflow during the course of sessions; obtaining computerized treatment data after initiating the course of sessions; processing the computerized treatment data, using the processor circuit, to determine an indication of delivery or effect of the radiation treatment during the course of sessions based on the initial patient care plan relative to the workflow; using the indication of delivery or effect of the radiation treatment to adapt the patient care plan; and managing the workflow for the patient using the adapted patient care plan as the patient proceeds through a course of sessions.

Methods and systems for monitoring an automated radiopharmaceutical infusion apparatus are disclosed. A user interface graphically representing infusion apparatus components may be presented on a display device. Multiple sensors may be arranged within an infusion apparatus to measure property information associated with infusion apparatus components, including fluid pathways. The property information may include radioactivity and flow information. The property information may be compared with expected results. If the property information does not match the expected results, a fault condition may be indicated on the display device. The user interface may provide information and/or functions to manage the fault conditions.

A radiation treatment system is described, including a linear accelerator (LINAC), having a housing, to emit a treatment beam to a target location and a Cerenkov emission detector, coupled to the housing of the LINAC, to capture a set of images of optical Cerenkov emission generated at the target location by charged particles of the treatment beam. A method is described including emitting the treatment beam from the LINAC to the target location and capturing, using the Cerenkov emission detector coupled to the LINAC, the set of images of optical Cerenkov emission generated at the target location by the treatment beam.

The invention relates to a particle energy measuring device (14) for determining the energy of a particle beam (26) with (a) at least twenty capacitors (30.n) that (i) each comprise a first capacitor plate (32.n) and (ii) a second capacitor plate (34.n), and (iii) are arranged one behind the other with respect to a beam incidence direction (S), (b) a multiplexer (46) that has (i) a multiplexer outlet (48) and (ii) a plurality of multiplexer inputs (50.n), each multiplexer input (50.n) being designed to connect to precisely one capacitor (30.n) and (iii) that is configured to connect one of the capacitor plates (32.n, 34.n) of the respective capacitor to the multiplexer outlet (48), (c) a total charge measuring device (52) that (i) comprises a total charge measuring device in-put (54), which is connected to the second capacitor plates (34.n) in order to detect a total charge (q-) of the charges on all the capacitors (30.n), and (d) a total charge measuring device outlet (56), and (d) an analysis circuit (58) that (i) is connected to the total charge measuring device (52) and the multiplexer (46), and is designed to automatically (i) effect a switch from one multiplexer input (50.n) to another multi-plexer input (50.n), so that the capacitors are individually discharged in succession and (ii) detect the charge (Qn) flowing from each capacitor (30.n) during the discharging process, thereby obtaining charging data from which the particle energy (E) can be calculated.

Systems and methods for determining beam asymmetry in a radiation treatment system using electronic portal imaging devices (EPIDs) without implementation of elaborate and complex EPID calibration procedures. The beam asymmetry is determined based on radiation scattered from different points in the radiation beam and measured with the same region of interest ROI of the EPID.