A neutron capture therapy system, including a beam shaping assembly, and a vacuum tube and at least one cooling device. The beam shaping assembly includes a beam inlet, an accommodating cavity accommodating the vacuum tube, a moderator adjacent to an end portion of the accommodation cavity, a reflector surrounding the moderator, and a radiation shield and a beam outlet arranged in the beam shaping assembly. An end portion of the vacuum tube is provided with a target. The cooling device undergoes a nuclear reaction with a charged particle beam incident from the beam inlet to produce neutrons. The moderator decelerates the neutrons produced by the target to an epithermal neutron energy region. The reflector leads deviating neutrons back to the moderator. At least one accommodating pipeline accommodating the cooling device is arranged in the beam shaping assembly. A filler is filled between the cooling device and the accommodating pipeline.

Biodegradable Periodic Mesoporous Organosilica (BPMO) nanomaterials and methods of making BPMOs loaded with Neutron Capture Agents are disclosed herein. Consequently, the BPMOs loaded with Neutron Capture Agents provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.

It is an object to provide an imaging method and system. According to an embodiment, an imaging method comprises emitting neutrons into a material, wherein the material converts at least part of the emitted neutrons into a first plurality of gamma ray photons, and wherein at least part of the emitted neutrons pass through the material. Based on the neutrons passed through the material and the gamma ray photons, at least one property of the material can be deduced. An imaging method and an imaging system are provided.

A therapeutic apparatus may be provided. The therapeutic apparatus may include a magnetic resonance imaging (MRI) device configured to acquire MRI data with respect to a region of interest (ROI) and a radiation therapy device configured to apply therapeutic radiation to at least one portion of the ROI. The MRI device may include an annular cryostat having one or more chambers, an annular structure assembly and a recess disposed on the annular structure arrangement. The radiation therapy device may at least include an accelerator and one or more collimation components.

An irradiation parameter selection apparatus (71) and a usage method thereof and a control system (7) comprising the irradiation parameter selection apparatus (71) and a usage method thereof, the irradiation parameters comprising irradiation points and irradiation angles, and the irradiation parameter selection apparatus (71) comprising: a sampling part (711) for selecting multiple sets of irradiation points and irradiation angles; a calculation part (712) for calculating an evaluation value corresponding to the multiple sets of irradiation points and irradiation angles; and a selection part (713) for selecting the best set of implementable irradiation points and irradiation angles from all of the sampled irradiation points and irradiation angles on the basis of the evaluation values calculated by the calculation part (712).

Single-use brachytherapy systems for application of beta radiation to a target tissue, and methods of use. The single-use brachytherapy systems herein feature a cap into which a radionuclide brachytherapy source (RBS) can be inserted and a handle that removably attaches to the cap. When the handle is disengaged from the cap in order to access the RBS, the system is rendered useless for its original purpose, for its use as it was originally intended, for its use as prescribed, unless repaired.

Particle radiation therapy and planning utilizing magnetic resonance imaging (MRI) data. Radiation therapy prescription information and patient MRI data can be received and a radiation therapy treatment plan can be determined for use with a particle beam. The treatment plan can utilize the radiation therapy prescription information and the patient MRI data to account for interaction properties of soft tissues in the patient through which the particle beam passes. Patient MRI data may be received from a magnetic resonance imaging system integrated with the particle radiation therapy system. MRI data acquired during treatment may also be utilized to modify or optimize the particle radiation therapy treatment.

Embodiments of systems, devices, and methods relate to an electrode standoff isolator. An example electrode standoff isolator includes a plurality of adjacent insulative segments positioned between a proximal end and a distal end of the electrode standoff isolator. A geometry of the adjacent insulative is configured to guard a surface area of the electrode standoff isolator against deposition of a conductive layer of gaseous phase materials from a filament of an ion source.

A gantry-less particle therapy system is provided. Charged particles are extracted from an ion source and accelerated in a beam transport system having an annular portion extending in a first plane and that circumscribes a volume, an arcuate portion extending in a second plane, and a transition portion that connects the annular portion and the arcuate portion. The arcuate portion terminates at a beam nozzle extending radially inward from the annular portion to deliver an ion beam to a treatment area contained in the volume circumscribed by the annular portion.

A beam target for generating a nuclear reaction product by irradiation with a beam obtained from a beam generation source includes a cone body which has a tapered inner surface which is reduced in diameter toward a tip, and supply means for supplying liquid metal to the inner surface of the cone body to form a liquid film of the liquid metal on the inner surface. It is possible to form the liquid film of the liquid metal on a cone body surface to increase an irradiation area of the beam, and also dispose a target substance such as LLFP around the cone body, and hence it is possible to efficiently use the nuclear reaction product (e.g., a neutron) generated by beam irradiation of the liquid metal.