Devices for localizing an intracerebral hematoma or blood mass in brain tissue. The devices include an elongate probe a color sensors and a light emitter on the distal end of the probe. The color sensors produce a signal corresponding to the color of light reflected into the color sensors. A display is provided to indicate the color detected.

An imaging method of a fluorescent image performs image processing before generating colored-fluorescent images, including steps: respectively imaging the red, green and blue lights of the white light on three monochromatic sensors under the precondition that the software processing speed is not affected; imaging the near infrared fluorescent light on one of the monochromatic sensors; determining whether the sensor used to receive the near infrared fluorescent light receives the fluorescent signal; calculating the light intensity received by the sensor receiving the fluorescent signal and the light intensities received by the other two sensors; automatically adjusting the projection intensity of the white light source and/or the excitation light source according to the difference of the intensities of the two types of light signals, whereby a closed-loop system is formed to simultaneously present the colored-florescent images on a picture with the best contrast.

A reflectionless window is disclosed. The reflectionless window comprises: a transparent window; a plurality of first nanocolumns arranged on a first surface of the transparent window; and a plurality of second nanocolumns having a height smaller than that of the first nanocolumns, the plurality of second nanocolumns being arranged on at least one surface selected from the upper surface of the plurality of first nanocolumns and a side surface thereof and being arranged in an area on the first surface of the transparent window in which the plurality of first nanocolumns are not arranged.

A system for acquiring physiological data from a patient, the system comprising: a smartphone configured for wireless communication; an adapter for releasably mounting to the smartphone; a sensor module for releasably mounting to the adapter, the sensor module comprising at least one sensor for acquiring physiological data from the patient; and a software app running on the smartphone for (i) wirelessly controlling operation of the sensor module and wirelessly receiving the physiological data from the sensor module, and (ii) wirelessly communicating with a remote location.

A measurement system is provided with an array of laser diodes with one or more Bragg reflectors. At least a portion of the light generated by the array is configured to penetrate tissue comprising skin. A detection system configured to: measure a phase shift, and a time-of-flight, of at least a portion of the light from the array of laser diodes reflected from the tissue relative to the portion of the light generated by the array; generate one or more images of the tissue; detect oxy- or deoxy-hemoglobin in the tissue; non-invasively measure blood in blood vessels within or below a dermis layer within the skin; measure one or more physiological parameters based at least in part on the non-invasively measured blood; and measure a variation in the blood or physiological parameter over a period of time.

A surgical instrument may comprise an elongated shaft extending between a proximal end and a distal end and defining a longitudinal axis. The surgical instrument may also comprise a plurality of cables extending along the longitudinal axis and a first bending section positioned between the proximal end and the distal end of the elongated shaft. The first bending section may comprise links having pairs of articulation holes extending longitudinally through the links to permit the plurality of pull wires to pass therethrough. Each pair of articulation holes may comprise first and second articulation holes that are spaced apart from the longitudinal axis (i) at different radii and (ii) at a same rotation angle.

A system for performing a surgical procedure includes a camera configured to capture real-time near infrared images, an injection system configured to inject a fluorescent dye into a patient's blood stream, and a workstation operably coupled to the camera for retrieving a three-dimensional (3D) model of the patient's anatomy based on pre-procedure images, retrieve an indication of a targeted critical structure within the 3D model, observe, using the captured real-time near infrared images, perfusion of the fluorescent dye through tissue to identify critical structures illuminated by near-infrared light, and register the real-time near-infrared images to the 3D model using the identified illuminated targeted critical structure in the real-time near infrared images captured by the camera and the identified targeted critical structure in the 3D model as a landmark.

A surgical system comprises a manipulator arm, configured to secure to a base, and an actuator assembly. The actuator assembly includes an instrument mounting bracket and a plurality of actuator disks supported on a first end of the instrument mounting bracket. The surgical system also includes a surgical instrument including a plurality of interface disks supported on a face of the surgical instrument. The plurality of interface disks is configured to mate with the plurality of actuator disks. The instrument also includes an attachment mechanism configured to removably attach the surgical instrument to the actuator assembly and an instrument body tube extending from the face of the surgical instrument. The instrument body tube is capable of passing by or passing through the instrument mounting bracket when the surgical instrument is attached to the instrument mounting bracket.

A Raman endoscope for use in obtaining in vivo Raman spectra in the peripheral airways of the lungs and a method of constructing the Raman endoscope are disclosed. The endoscope has a tubular sheath containing a fiber bundle. The sheath has an outer diameter of less than 1.35 mm. The sheath is made of fluorinated ethylene propylene. The sheath is flexible along its length from a first end to a point along the sheath so that it can navigate sharp turns within the peripheral airways. A layer of coating covers the sheath along a terminal length and a probe tip of the fiber bundle. The terminal length extends along a length of the sheath extending from a second end opposite to the first end to the point. Terminal length is rigid to facilitate advancement of the endoscope towards the lesion of interest. Terminal length is 5 mm or less.

One aspect of the invention relates to a method for intraoperative detection of parathyroid gland viability in a surgery, comprising obtaining speckle contrast images of a parathyroid gland of a patent; and displaying the speckle contrast images of the parathyroid gland in real-time.