An embodiment of a method for assessing cardiovascular disease in a user with a body region using a mobile computing device including a camera module, includes receiving a time series of image data of a body region of the user, the time series of image data captured during a time period; generating a photoplethysmogram dataset from the time series of image data; generating a processed PPG dataset; determining a cardiovascular parameter value of the user based on the processed PPG dataset; fitting a chronobiological model to (1) the cardiovascular parameter value, and (2) a subsequent cardiovascular parameter value, characterizing a cardiovascular parameter variation over time of the user based on the fitted chronobiological model; and presenting an analysis of the cardiovascular parameter variation to the user at the mobile computing device.

An apparatus for estimating bio-information includes: a sensor part configured to obtain contact pressure of a contact surface contacted by an object, and configured to obtain a contact image of the object that contacts the contact surface; and a processor configured to obtain a pulse wave signal of a region of interest based on the contact image, and configured to estimate bio-information based on the obtained pulse wave signal and the contact pressure.

A method of detecting hypertension in a patient having an implantable blood pump, the method includes operating the implantable blood pump at a first pump set speed during a first period of time. A first flow rate minimum during a cardiac cycle of the patient is measured during the first period of time. The first pump set speed is reduced by at least 200 rpm during a second period of time after the first period of time to a second pump set speed, the second period of time being less than the first period of time. A second flow rate minimum is measured during a cardiac cycle during the second period of time. If the second flow rate minimum decreases during the second period of time at the second pump set speed by more than a predetermined amount, an alert is generated indicating a presence of hypertension.

There is a method and system for detecting heartbeat irregularities comprising the steps of receiving a dataset representative of at least one waveform, the at least one waveform indicative of a subject's heart activity over a predetermined period of time; identifying from the data representative of at least one waveform, a plurality of peaks, each peak corresponding to a heartbeat; identifying from the predetermined period of time the time occurrence of each peak; calculating the difference (duration) between the time occurrence of each peak with its adjacent peak; determining the difference between each duration; classifying the absolute value of the difference into one of at least three intermediate categories; wherein each intermediate category comprises a specified range such that the absolute value is categorized into the intermediate category if it falls between the range; the intermediate categories further providing an indication of whether the subject has heartbeat irregularity.

The invention describes a measuring system for the continuous non-invasive determination of blood pressure at one or more fingers. The fingers chosen for measurement and the adjacent parts of the palm rest on a supporting surface of a housing, which has the shape of a computer mouse. Inside the housing of the “CNAP Mouse”, i.e. underneath the supporting surface for the hand, the pressure generating system is located. The finger sensors are mounted on the supporting surface for the hand. The forearm and the back of the hand are left free and may be used to place intra-venous or intra-arterial access elements. Since the hand will rest on the supporting surface motion artefacts are largely avoided. Tilting or turning of the sensors is hardly possible since the fit of the sensors and thus the coupling of light and pressure are optimized.

Method and system for evaluating arterial pressure waves, vascular properties, as well as for diagnostic, physiological and pharmacological testing using various combinations of the following data acquisition and processing steps (some of the steps are optional): 1. Perturbing arterial pressure from its steady state. 2. Measuring the dynamics of at least one parameter related to the passage of arterial pressure waves along blood vessels. 3. Characterizing the magnitude and functional relation of changes in parameters described above in relation to changes in blood pressure during its displacement from and/or return to the steady state. 4. Classifying (comparing) the individual functional relation described above with a databank of parameters/functional relations for different states of vasomotor activity.

Embodiments of the present disclosure disclose a method for detecting an effective pulse wave and provide a sphygmomanometer and a method for controlling the sphygmomanometer. The method for detecting the effective pulse wave may include: selecting a pulse wave controlling parameter; setting an initial pulse wave controlling parameter; determining at least one pulse wave based on the initial pulse wave controlling parameter, determining a corrected initial pulse control parameter by correcting the initial pulse wave controlling parameter based on at least one pulse wave controlling parameter of the at least one pulse wave; determining at least one subsequent pulse wave based on the corrected initial pulse wave controlling parameter, and further correcting the corrected pulse wave controlling parameter based on at least one pulse wave controlling parameter of the at least one subsequent pulse wave; and repeating above iterative process and continuously correcting the initial pulse wave controlling parameter, and extracting at least one effective pulse wave based on the pulse wave controlling parameter after the correction. The present disclosure may be closer to an actual situation of a measured subject by correcting the initial pulse wave controlling parameter continuously, thereby filtering out a detected invalid pulse wave and avoiding missing detection of the effective pulse wave.

A device for measuring brachial arterial blood pressure in an individual has a blood pressure cuff attachable to an upper arm, means, separate to the blood pressure cuff, for measuring the heart rate, and a control unit connected to both the blood pressure cuff and the heart rate monitoring means, such that, in use, the control unit monitors the heart rate for the establishment of a stable resting heart rate, initiates a blood pressure measurement, and calculates the pulse pressure (PP) to establish the status of the brachial artery during the blood pressure measurement. Where the heart rate drops to within +12 bpm of a reference, resting heart rate for the individual the device will initiate a blood pressure measurement in accordance with a reference, resting heart rate protocol. However, where an irregular heart rate (IRHR) is found the device will initiate a blood pressure measurement in accordance with a timed protocol.

A display device capable of measuring a user's blood pressure by analyzing a photoplethysmographic signal is disclosed. The display device includes a display panel including a plurality of pixels; a force sensor disposed on a surface of the display panel, the force sensor configured to sense an external force; a light receiving sensor disposed between a group of neighboring pixels of the plurality of pixels, or disposed in a through hole in a front portion of the display panel, the light receiving sensor configured to sense an amount of light reflected toward the display panel and generate an optical signal corresponding to the amount of light; and a main processor configured to generate a pulse wave signal according to the optical signal received from the light receiving sensor and analyze a magnitude, a period, and a wave change of the pulse wave signal.

Modular, miniaturized cardiovascular sensors, systems, methods, and wearable devices for the non-obtrusive evaluation, monitoring, and high-fidelity mapping of cardiac mechanical and electromechanical forces and central arterial blood pressure are presented herein. The sensor manufacturing process is also presented. Using accelerometers, the sensors register body-surface (preferably torso-surface) movements and vibrations generated by cardiac forces. The sensors may contain single-use or reusable components, which may be exchanged to fit different body sizes, shapes, and anatomical locations; they may be incorporated into clothing, bands, straps, and other wearable arrangements. The invention presents a practical, noninvasive solution for electromechanical mapping of the heart, which is useful for a wide range of healthcare applications, including the remote monitoring of heart failure status and the guidance of cardiac resynchronization therapy. Exercise and cardiovascular fitness tracking applications are also presented.