Devices and systems compare incoming and outgoing gas and fluid flowrate measurements with each other and with additional physiological measurements of a patient to trigger an alarm to healthcare providers of an issue with a patient. The device can include a sensor that measures incoming flow of gas and fluid and a sensor for measuring the outgoing flow of gas and fluid (for example, urine) from the patient. The sensors can be connected to wireless transmitters to send data describing the flow to a computer processor. The computer processor receives the data from the processors and generates an alarm based on comparisons between the input flow and the output flow. The devices and system can be used to detect issues in a patient by monitoring a flow of intravenous fluids being administered to an amount of urine being generated. The devices and system can be used to detect issues in a patient by comparing a flow of gas being administered to a patient compared to blood gas content in the patient.

A monitoring device detects a disruption of a fluid connection between first and second fluid containing systems using one or more pressure sensors arranged in the first fluid containing system to detect first pulses from the first fluid containing system and second pulses from the second fluid containing system. The monitoring device receives (501) pressure signal(s) from the pressure sensor(s), populates (504) signal vectors by signal segments in the pressure signal(s) and computes (505) one or more eigenvectors and/or one or more eigenvalues for the signal vectors by a source separation algorithm. The monitoring device detects (506) the disruption based on a monitoring parameter, which is computed as a function of the eigenvector(s) and/or eigenvalue(s) to be responsive to the second pulses in the pressure signal(s). The monitoring device may be associated with or included in an apparatus for extracorporeal blood processing, such as a dialysis machine.

The disclosed devices and methods provide for the minimization of fluid extravasation during use of infusion catheters such as peripherally inserted central catheters and central venous catheters. The anti-extravasation catheter allows a surgeon to drain fluids from soft tissue surrounding an infusion site while also providing fluid inflow to a patient.

Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. In one embodiment, the system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and then performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time. When the IV line functionality indicates IV infiltration, the processing device may control the fluid controlling device to stop the fluid flow from the fluid source to the IV catheter.

A non-invasive method of calculating the central venous pressure (CVP) of a patient may include analysis of video of the neck region of the patient. Filters, which may include spatial filters and/or temporal filters, may be applied to the video to enhance the visibility of small movements, which may be due to circulatory pulsations of the patient. The video may be modified to highlight such movements, and motion indicative of venous pulsation may be distinctly identified and highlighted.

A sensor guide wire includes a sensor element arranged in a jacket in a sensor region of the sensor guide wire; a core wire extending at least partly along a length of the sensor guide wire; and at least one electrical lead connected to the sensor element. The jacket is tubular and includes proximal and distal end openings, a jacket wall, a first opening arranged in the jacket wall, and a second opening arranged in the jacket wall, the first and second openings being proximate to the sensor element. The core wire is adapted to extend through the jacket via the proximal and distal end openings. At least a portion of the first opening and at least a portion of the second opening are both located in the same cross-section of the sensor guide wire, the cross-section being perpendicular to the longitudinal axis of the sensor guide wire.

A first venous rhythm of a patient is detected above a venous insertion site when a venous catheter connected to an infusion set is inserted into the venous insertion site and, concurrently with the first venous rhythm, a second venous rhythm is detected at a location remote from the venous insertion site. An irregularity between the first and second venous rhythms is identified, and a failure of the venous catheter is determined based on the identified irregularity satisfying a irregularity threshold. An alarm may be provided on detecting the irregularity or the failure of the venous catheter.

A system and apparatus for utilizing invasive techniques to determine the blood pressure of a patient, are provided. An example system may include a pressure sensor, an intravenous fluid supply bag, and a hollow needle configured to penetrate a blood vessel of a patient. An intravenous supply tube may fluidly connect the pressure sensor to the hollow needle. A lumen filled with an incompressible fluid may be disposed within the intravenous supply tube. The lumen may be coupled to the pressure sensor at one end and terminate in a flexible membrane at the other end. The flexible membrane may deform in response to a blood pressure wave transmitted from the blood vessel of the patient, and transmit the blood pressure wave through the incompressible fluid and to the pressure sensor. The pressure sensor may determine a blood pressure measurement based at least in part on the received blood pressure wave.

Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.

Disclosed is an implant and method of making an implant. The implant having a housing that defines a cavity. The housing includes a sensor comprising a base attached to a diaphragm wherein said base may be positioned within said cavity. The sensor may be a capacitive pressure sensor. The diaphragm may be connected to the housing to hermetically seal said housing. The sensor may include electrical contacts positioned on the diaphragm. The attachment between the base and the diaphragm may define a capacitive gap and at least one discontinuity configured to enhance at least one performance parameter of said implant.