A device for the detection of endovascular pressure of a fluid in a vessel detects through an air column which inside capillary ducts, is in contact with endovascular fluid which exerts its pressure thereon, by separating such air column from outside in each process phase, and then prevents that the fluid from being polluted or infected thereby, and including a connector with a valve, which defines a connection terminal cavity arranged outside a needle-holding element and is in fluid communication with the capillary ducts through a duct extending from the needle-holding element to the connector; and a re-usable element including a pressure sensor and connector to connect to the connector at the terminal cavity of the disposable portion, which receives the pressure sensor, with the terminal cavity, the opening of the valve being determined by the connection between the re-usable element and the disposable portion.

Systems and methods are described for the compositing together of model-linked vascular data from a plurality of sources, including at least one 2-D angiography image, for display in a frame of reference of the at least one angiography image. In some embodiments, a linking model comprises a data structure configured to link locations of angiographic images to corresponding elements of non-image vascular parameter data. The linking data structure is traversed to obtain a mapping to the frame of reference of one or more of the angiographic images.

Methods and systems are provided for diagnosis and/or treatment of microvascular dysfunction, such as microvascular obstruction (MVO), in which the effects of collateral flow around a treatment site are addressed by injecting volumetric flows into a vessel using an infusion system to prevent or render negligible the collateral flow. Arterial pressures and fluidic flow rates sufficient to negate the collateral flow may be used to indicate the presence and/or severity of MVO for diagnostic and/or therapeutic purposes.

Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. The methods can include obtaining pressure measurements from first and second instruments positioned within a vessel of a patient while the second instrument is moved longitudinally through the vessel from a first position to a second position and the first instrument remains stationary within the vessel; and outputting a visual representation of the pressure measurements obtained by the first and second instruments on a display, the output visual representation including a graphical display of a pressure ratio of the obtained pressure measurements and at least a portion of a pressure waveform of the obtained pressure measurements identifying a diagnostic period utilized in calculating the pressure ratio.

The present invention relates to an apparatus and a method for determining an indication of blood flow in a limb. According to an embodiment, the apparatus comprises an orientation sensor, a blood volume (BV) measuring device and a control unit. The orientation sensor is configured to determine an orientation of the limb and output an orientation signal indicative thereof. The blood volume measurement device is configured to measure an indication of blood volume (BV) in the limb and output a BV signal indicative thereof. The control unit is arranged to receive the orientation signal and the BV signal, determine a change in orientation of the limb in dependence on the orientation signal, and correlate the change in orientation with a change in blood volume of the limb determined in dependence on the BV signal.

A catheter assembly or other elongate tubular device for use in establishing vascular or other access within the body of a patient is disclosed. The catheter assembly is equipped with one or more sensors that enable monitoring of one or more physiological aspects of the patient or physical aspect of the catheter assembly itself when the catheter assembly is disposed within the patient. Such aspects include central venous pressure, body temperature, ECG heart signals, oxygen levels, ultrasound data, glucose, etc. The catheter assembly includes the ability to wirelessly transmit or otherwise forward data relating to the detected physiological parameters to another location, such as a patient electronic medical record, smartphone or other mobile device, nurse station, etc. Catheter assemblies configured to detect the frequency of catheter flushing, flushing quality, etc., are also disclosed.

A monitoring system performs a method for detecting a disruption of a fluid connection between a first fluid containing system and a second fluid containing system. The monitoring system generates a monitoring signal which is representative of a fluid pressure in respect of the first fluid containing system and which is responsive to the disruption of the fluid connection, and a tracking signal which corresponds to and is more smoothed over time than the monitoring signal. The monitoring system further sets a detection range in a given relation to the tracking signal so that the detection range follows changes in the tracking signal, and detects a condition indicative of the disruption by comparing a current pressure value of the monitoring signal to the detection range. The monitoring system may be connected to or part of an apparatus for blood treatment and operable to detect a disconnection of an extracorporeal blood circuit from a vascular system of a patient, e.g. downstream of a blood pump in the extracorporeal blood circuit.

Devices, systems, and methods of mapping a vessel system of a patient and identifying lesions therein are disclosed. This includes a method of evaluating a vessel of a patient, the method comprising obtaining image data for the vessel of the patient, obtaining physiological measurements for the vessel of the patient, co-registering the obtained physiological measurements with the obtained image data such that the physiological measurements are associated with corresponding portions of the vessel of the patient, analyzing the co-registered physiology measurements to determine a classification of a lesion within the vessel of the patient, and outputting, to a user interface, the classification of the lesion. Other associated methods, systems, and devices are also provided herein.

An identification system including a first biometric identifier, a second biometric identifier, a first cardiac identifier logically related to the first biometric identifier, a second cardiac identifier logically related to the second biometric identifier, where the identity of a user is verified using the biometric identifiers and the cardiac identifiers.

Disclosed is an implant and method of making an implant. The implant having a housing that defines a cavity. The housing includes a sensor comprising a base attached to a diaphragm wherein said base may be positioned within said cavity. The sensor may be a capacitive pressure sensor. The diaphragm may be connected to the housing to hermetically seal said housing. The sensor may include electrical contacts positioned on the diaphragm. The attachment between the base and the diaphragm may define a capacitive gap and at least one discontinuity configured to enhance at least one performance parameter of said implant.