A device for the detection of endovascular pressure of a fluid in a vessel detects through an air column which inside capillary ducts, is in contact with endovascular fluid which exerts its pressure thereon, by separating such air column from outside in each process phase, and then prevents that the fluid from being polluted or infected thereby, and including a connector with a valve, which defines a connection terminal cavity arranged outside a needle-holding element and is in fluid communication with the capillary ducts through a duct extending from the needle-holding element to the connector; and a re-usable element including a pressure sensor and connector to connect to the connector at the terminal cavity of the disposable portion, which receives the pressure sensor, with the terminal cavity, the opening of the valve being determined by the connection between the re-usable element and the disposable portion.

Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.

Systems, devices, and methods for organ Retroperfusion along with regional mild hypothermia. One such system includes a hypothermia system including a hypothermia system outlet and a hypothermia system inlet; and a connector comprising a coolant inlet, a coolant outlet, a coolant reservoir, and a blood lumen, whereby the coolant inlet is configured to couple to the hypothermia system outlet and whereby the coolant outlet is configured to couple to the hypothermia system inlet; whereby a cooling product, when the hypothermia system is connected to the connector, can flow from the hypothermia system, through the hypothermia system outlet, into the coolant inlet, through the coolant reservoir, into the coolant outlet, and into the hypothermia system inlet, so that the cooling product can cool blood flowing through the blood lumen.

Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.

Peripheral intravenous (IV) waveform analysis (PIVA) systems and methods for determining an intravascular volume status of a living subject and monitoring an IV line functionality of a peripheral IV device are provided. The PIVA system includes a peripheral IV device and a processing device. The peripheral IV device includes a peripheral IV catheter inserted into a vein of the living subject, and a fluid controlling device to control fluid flow from a fluid source to the peripheral IV catheter. The processing device receives peripheral venous signals from the peripheral IV device, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum; and performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an intravascular volume status of the living subject and/or an IV line functionality of the peripheral IV catheter in real time.

Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices are guide wires that include a capacitive pressure-sensing component disposed at a distal portion of the guide wire. Methods of making such intravascular devices, including various manufacturing and assembling techniques, are disclosed. Systems associated with such intravascular devices and methods of using such devices and systems are also disclosed.

The present invention provides an arteriovenous pressure measurement device which allows noninvasive and accurate measurement of arteriovenous pressure, and also provides an arteriovenous pressure measurement method using the measurement device. The noninvasive arteriovenous pressure measurement device comprises a probe (20) for radiating ultrasound toward a blood vessel in the skin, a pressing part (10) for pressing the skin in a state of being placed between the skin and the probe (20), and a pressure sensor (33) for detecting a pressing force applied to the skin at the pressing part (10), the pressing part (10) having water (36) permeable to the ultrasound and a balloon (31) accommodating the water (36), the flexible container (31) being made of a flexible material permeable to the ultrasound, and an outer surface of the balloon (31) presses the skin.

Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.

The invention described herein is a method that can predict: according to a Modality A, the effort capacity of a human individual as an expression of distance walked by the individual if subjected to a 6MWT; and according to Modality B, the hemodynamic state of the patient as an expression of CI and SVR. The method is comprised of four steps: (1) capturing a series of thermal images of the face and hands of a human individual, according to the modality; (2) applying established temperature values for a series of specific spots from the face and the hands, according to the modality; (3) selecting general additional parameters, from the patient and the environment; and (4) implementing algorithms discovered through the ML technique, through which the previously mentioned parameters are analyzed

The invention described herein is a method that can predict: according to a Modality A, the effort capacity of a human individual as an expression of distance walked by the individual if subjected to a 6MWT; and according to Modality B, the hemodynamic state of the patient as an expression of CI and SVR. The method is comprised of four steps: (1) capturing a series of thermal images of the face and hands of a human individual, according to the modality; (2) applying established temperature values for a series of specific spots from the face and the hands, according to the modality; (3) selecting general additional parameters, from the patient and the environment; and (4) implementing algorithms discovered through the ML technique, through which the previously mentioned parameters are analyzed