There is described a pressure guidewire. It comprises a sensor housing and a sensor assembly embedded in the sensor housing and comprising a pressure sensor. There is a band to support the pressure sensor assembly, the band being embedded inside the sensor housing and fixed to the pressure sensor assembly for holding the pressure sensor inside the sensor housing.

An optical channel, of an optical filter, passes light associated with a particular wavelength range to a sensor element, of an optical sensor, that operates in a gated mode. One or more processors obtain, from the optical sensor, a first optical measurement and a second optical measurement related to a multi-layered subject. The first optical measurement indicates an amount of light associated with the particular wavelength range that the sensor element accumulated during a first time range, and the second optical measurement indicates an amount of light associated with the particular wavelength range that the sensor element accumulated during a second time range. The first time range is a subrange of the second time range. The one or more processors process the first optical measurement and the second optical measurement to determine one or more parameters associated with the multi-layered subject.

A sleep apnea and obesity comorbidity treatment system includes a transceiver and a control module. The control module is configured to: receive sensor data, where the sensor data is indicative of a glucose level of a patient and a ketones level of the patient, transmit the sensor data to a remote feedback device, receive feedback information from the remote feedback device based on the sensor data, and where the feedback information provides indications to the patient to maintain or alter a behavior of the patient based on the glucose level and the ketones level, and based on the feedback information, performing an operation to maintain or alter at least one of a diet or physical activity of the patient.

The invention relates to a system for determining blood flow within a blood vessel (18). A fluid infusion unit (4, 10, 11) continuously infuses a fluid into the blood vessel, and a temperature values determining unit (14, 21) determines simultaneously a first temperature value at a first location and a second temperature value at a second location such that the first temperature value is indicative of the temperature of the fluid and the second temperature value is indicative of the temperature of a mixture of the fluid and the blood. The blood flow is determined based on the measured first and second temperature values and the infusion rate. This kind of determining the blood flow leads to an increased accuracy and is less cumbersome than known techniques requiring a movement of a temperature sensor for measuring temperatures at different locations.

Strain-sensing systems, indwelling medical devices, and methods for determining one or more physical attributes are disclosed. A strain-sensing system can include, for example, an indwelling medical device, an optical interrogator, and a console. The medical device can include an optical-fiber probe having fiber Bragg grating (“FBG”) sensors. The optical interrogator can be configured to send input optical signals into the optical-fiber probe and receive FBG sensor-reflected optical signals therefrom. The console can include one or more processors, memory, and executable instructions that cause the console to perform a set of operations including: receiving the FBG sensor-reflected optical signals from the optical interrogator; converting the FBG sensor-reflected optical signals into converted electrical signals with optical signal-converter logic; and determining in a real-time determination the one-or-more physical attributes associated with a heart, lungs, or both the heart and lungs from at least the converted electrical signals with physical attribute-determination logic.

A method of determining one or more diagnostic metrics to assess a blood vessel using intravascular data includes: sampling a sensor of an intravascular data collection probe disposed in the blood vessel during a pullback of the intravascular data collection probe through the blood vessel to obtain sampled distal pressure (Pd) values; receiving, at an intravascular data processing system, the sampled distal pressure (Pd) values and proximal pressure (Pa) values; determining sets of Pd/Pa ratios, each set including Pd/Pa ratios that are determined through an entirety of one heart cycle; determining minimum Pd/Pa ratios, each of which is a minimum within one of the sets of Pd/Pa ratios over the entirety of the corresponding heart cycle; and controlling a display system to generate a plot of a moving average of the minimum Pd/Pa ratios over time during the pullback.

The present invention relates to systems, methods and algorithms for determination of heart pump function and their use in livings subject are described.

The invention further relates to complementary parts of such systems that work best in combination.

Medical catheters, sheaths and shafts are disclosed that carry an arrangement of integrated digital sensor systems-on-chip (SoC) in the portion thereof residing inside the body. These devices combine at their portion that resides inside the body, the complete chain of signal transduction, signal analog-to-digital conversion and digital signal transmission, and allow to acquire single and multiple physical entities in a single setup. In specific instances the devices integrate wireless data transfer functionality, and in specific instances they integrate wireless energy harvesting for battery-free functionality.

The present invention further describes complementary monitor systems that are suited for reception, processing and analysis of data acquired by such catheters/sheaths/shafts to yield a robust assessment of cardiac performance.

Moreover, the present invention relates to innovations which render such systems applicable to patients with and without cardiac assist devices.

The present invention relates to devices and methods for measuring physiological parameters, such as flow, pressure, temperature, electric conductivity and/or visual indication of thrombus formation or deposits accumulations, prior to, during and/or after prosthetic heart valve implantation procedures.

Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

The present invention relates to systems, methods and algorithms for determination of heart pump function and their use in livings subject are described. The invention further relates to complementary parts of such systems that work best in combination. Medical catheters, sheaths and shafts are disclosed that carry an arrangement of integrated digital sensor systems-on-chip (SoC) in the portion thereof residing inside the body. These devices combine at their portion that resides inside the body, the complete chain of signal transduction, signal analog-to-digital conversion and digital signal transmission, and allow to acquire single and multiple physical entities in a single setup. In specific instances the devices integrate wireless data transfer functionality, and in specific instances they integrate wireless energy harvesting for battery-free functionality. The present invention further describes complementary monitor systems that are suited for reception, processing and analysis of data acquired by such catheters/sheaths/shafts to yield a robust assessment of cardiac performance. Moreover, the present invention relates to innovations which render such systems applicable to patients with and without cardiac assist devices.