Intravascular blood pressure monitoring devices and methods that include an indwelling portion and a pressure transducer. The indwelling portion may include a tubular member, at least a portion of the tubular member configured to transmit fluid pressure from blood that is external to the tubular member to a fluid disposed within the tubular member, and the tubular member may be adapted to isolate the fluid from the blood, with the fluid within the tubular member being in pressure communication with a pressure transducer. The devices may include a stiffening member interface adapted to releasably interface with a stiffening member to stiffen at least a portion of the indwelling portion while delivering the indwelling portion to a position within the subject, and causing the indwelling portion to be less stiff after its removal.

Method and systems are provided for reliable, convenient, self-administered, and cost-effective determination of central venous pressure. The noninvasive method and apparatus use changes in transmural pressure to create detectable changes in peripheral venous vascular volume for the determination of central venous pressure. Transmural pressure changes can be manifested by intravascular or extravascular pressure changes. The system is noninvasive and uses optical measurements of venous volume in the presence of transmural pressure changes. The relationship between the transmural pressure change and the change in vascular venous volume is combined with anatomical measurements to determine the central venous pressure of the subject. Central venous pressure can be used to determine hemodynamic status of the subject to include fluid overload in the heart failure patient.

Method and systems are provided for reliable, convenient, self-administered, and cost-effective determination of central venous pressure. The noninvasive method and apparatus use changes in transmural pressure to create detectable changes in peripheral venous vascular volume for the determination of central venous pressure. Transmural pressure changes can be manifested by intravascular or extravascular pressure changes. The system is noninvasive and uses optical measurements of venous volume in the presence of transmural pressure changes. The relationship between the transmural pressure change and the change in vascular venous volume is combined with anatomical measurements to determine the central venous pressure of the subject. Central venous pressure can be used to determine hemodynamic status of the subject to include fluid overload in the heart failure patient.

A method and apparatus for the concurrent treatment of multiple oral diseases and defects while promoting general oral hygiene utilizing electricity are provided for non-human animals. Electrodes are used to deliver an electrical current to the gingival tissues of a mouth in order to achieve a number of therapeutic, prophylactic, and regenerative benefits. These benefits include killing oral microbes, increasing oral vasodilation, reducing oral biofilm, improving oral blood circulation, reversing oral bone resorption, promoting oral osteogenesis, treating gum recession, and fostering gingival regeneration. Other benefits include the treatment of gingivitis, periodontitis, and oral malodor, and other systemic diseases correlated with oral pathogens.

A stair traversing device comprising a payload body for transporting a payload, a step frame, and a mechanism between the step frame and the payload body to move the step frame relative to the payload body along a cyclical path. The mechanism drives a movement of one of the payload body and the step frame along a first segment of the cyclical path from a retracted configuration to an extended configuration, and drives a movement of the other one of the payload body and the step frame along a second segment of the cyclical path back into the retracted configuration. The payload body and the step frame are configured to remain fixedly in position on a stair when the other one of the payload body and the step frame is moved. The mechanism is configured to maintain the relative orientation between the payload body and the stair.

A stair traversing device comprising a payload body for transporting a payload, a step frame, and a mechanism between the step frame and the payload body to move the step frame relative to the payload body along a cyclical path. The mechanism drives a movement of one of the payload body and the step frame along a first segment of the cyclical path from a retracted configuration to an extended configuration, and drives a movement of the other one of the payload body and the step frame along a second segment of the cyclical path back into the retracted configuration. The payload body and the step frame are configured to remain fixedly in position on a stair when the other one of the payload body and the step frame is moved. The mechanism is configured to maintain the relative orientation between the payload body and the stair.

A stair traversing device comprising a payload body for transporting a payload, a step frame, and a mechanism between the step frame and the payload body to move the step frame relative to the payload body along a cyclical path. The mechanism drives a movement of one of the payload body and the step frame along a first segment of the cyclical path from a retracted configuration to an extended configuration, and drives a movement of the other one of the payload body and the step frame along a second segment of the cyclical path back into the retracted configuration. The payload body and the step frame are configured to remain fixedly in position on a stair when the other one of the payload body and the step frame is moved. The mechanism is configured to maintain the relative orientation between the payload body and the stair.

A stair traversing device comprising a payload body for transporting a payload, a step frame, and a mechanism between the step frame and the payload body to move the step frame relative to the payload body along a cyclical path. The mechanism drives a movement of one of the payload body and the step frame along a first segment of the cyclical path from a retracted configuration to an extended configuration, and drives a movement of the other one of the payload body and the step frame along a second segment of the cyclical path back into the retracted configuration. The payload body and the step frame are configured to remain fixedly in position on a stair when the other one of the payload body and the step frame is moved. The mechanism is configured to maintain the relative orientation between the payload body and the stair.

A blood pressure information measurement device, including first and second fluid bags in the first fluid bag; a pressure mechanism increases/decreases pressure in an internal space of the first fluid bag and the pressure in the internal space of the second bag; a control unit controls operation of the pressure mechanism; a pressure detection device detects an internal pressure of the first and the second fluid bag; and a calculation unit that calculates blood pressure information detected by the device. In calculating blood pressure information, the control unit controls operation of the pressure increase/reduction mechanism after the internal space of one fluid bag of the first and second fluid bags pressurized and expanded until internal pressure of one fluid bag reaches a predetermined pressure, the internal space of the other fluid bag of the first and second fluid bags pressurized and expanded while the one bag is kept sealed.

A blood pressure meter includes a pump and a first fluid path provided inside a main body. The first fluid path feeds a fluid from the pump to a fluid bladder or discharges the fluid from the fluid bladder. A pressure sensor is mounted on a first substrate disposed inside the main body. A second fluid path that introduces the fluid from the fluid bladder to the pressure sensor is provided. The second fluid path includes an inlet pipe that is integrally formed with a sensor package that incorporates the pressure sensor, and extends straight between the fluid bladder and the pressure sensor. A second substrate on which a blood pressure measurement element is mounted is disposed in a space that is located between the first substrate and the fluid bladder in a thickness direction and is adjacent to the second fluid path in a planar direction.