Embodiments relate to devices, systems and methods for monitoring neuromuscular blockage. In an embodiment, a neuromuscular blockage monitoring system comprises a patch device comprising a unitary patch body, at least two electrodes and at least one sensor, the at least one sensor arranged between the at least two electrodes on the unitary patch body; and a stimulator device operatively coupled to the patch device and configured to provide at least one electrical signal to the at least two electrodes to stimulate a muscle motor point and to receive a signal from the at least one sensor related to a result of the stimulation of the muscle motor point.

The present invention provides systems and methods for management and orchestration of a fleet of remote Internet-of-Things (IoT) devices. The present invention includes a platform for onboarding, provisioning, and managing remote IoT devices throughout their lifetime. The platform includes portals for manufacturers, vendors, and consumers to access device data and sensor data collected by the devices. The data collected by the portal is used to control the fleet of remote IoT devices as well as make recommendations, e.g., for sleep promotion and stress reduction.

Method and systems are provided for monitoring neuromuscular blockade in patients during surgical procedures. The system and method utilizes a stimulator to provide stimulation to a nerve of the patient, such as train-of-four (TOF). Following such stimulation, the system and method monitors for muscle twitch reaction and, based upon the monitored muscle twitches, the system and method creates a neuromuscular blocking trend curve. The neuromuscular blocking trend curve provides an estimated time of recovery for the patient and provides the estimated recovery time to a clinician. The estimated recovery time allows the clinician to modify treatment of the patient to accelerate recovery if required.

A method and system to obtain and process data indicative of muscle reflexes for screening and/or diagnosing a patient with a brain injury or spinal cord injury, and especially for obtaining and processing data indicative of reflexes from the bulbospongiosus muscle. Certain embodiments employ a novel electromechanical probe for stimulating the bulbospongiosus muscle to identify a time of the stimulation so that electrical responses from electrodes on the patient's skin can be identified for analysis.

A method of monitoring depth of muscle relaxation of a patient includes determining a sedative drug effect of one or more sedative drugs on a patient based on at least one of drug delivery information and measured nervous system information. The sedative drug effect is then compared to a sedation criterion and, if the sedative drug effect fulfills the sedation criterion, then a neuromuscular transmission (NMT) monitor is controlled to apply a series of stimulation to a nerve of a patient and muscle responses of the patient are measured to obtain an NMT baseline. A neuromuscular blocking agent (NMBA) notice is then generated on a user interface after obtaining the NMT baseline.

A system automatically calculates drug infusion applicable to a patient to induce a satisfactory anesthetic state during surgery. The automatic calculation system would be determined by target values of physiological monitors to evaluate the patient's condition. Automatic infusion increases patient safety, reducing post-surgical morbidity and mortality, and reduces continuous decision-making by the specialist. An electronic system implements a MIMO-PID controller that calculates the infusion of various drugs on the basis of a control error defined by deviations in the patient's condition, which is analyzed by several monitors. The automatic drug infusions are determined by safety systems for preventing under and/or over infusion events and are complemented with correction and feedback systems.

A method and system for monitoring neuromuscular blockade in patients during surgical procedures. A stimulator provides stimulation to a nerve of the patient, such as train-of-four (TOF). Following such stimulation, the system and method creates a predicted recovery trend for the patient that is based upon measured recovery trend and a recovery model. The recovery model estimates a recovery trend for the patient based on initial model parameter values. The recovery model creates a predicted recovery trend that is used to estimate a recovery time for the patient. The trend values from the patient are monitored and compared to the predicted trend values throughout the operation as long as the NMT measurement is on. During recovery, the recovery model and recovery time estimates are updated based on the recovery trend being formed from measurements of the patient.

A system (SYS) and related method for imaging support. The system (SYS) comprises a stimulus delivery component (SDC) configured to cause a chemoreceptor stimulus in a patient residing in or at an imaging apparatus (IA). A response measuring component (RMC) measure a response of the patient to the stimulus, and a decision logic (DL) establishes, based on the measured response, a sedation status of the patient for the purpose of imaging the patient. An imaging operation can be modified, for instance, halted if the patient is no longer sufficiently sedated.

A system for nerve stimulation is provided; it comprises a nerve stimulation device configured to execute a set of nerve stimulation instructions for generating electrical pulses for nerve stimulation of a patient. A user electronic device is configured to generate the set of nerve stimulation instructions; and send the set of nerve stimulation instructions wirelessly to the nerve stimulation device.

A method of monitoring a patient for phrenic nerve collateral damage during a cardiac ablation procedure. The method includes measuring at least one from the group consisting of compound motor action potential (CMAP) and accelerometer signals in response to stimulating of the phrenic nerve. Real-time data is displayed on a display, the real-time data including the at least one from the group consisting of the measured CMAP and accelerometer signals. Long-term trend data is simultaneously displayed on the display, the long-term trend data being associated with the measured at least one from the group consisting of CMAP and accelerometer signals.