A system and method is disclosed for measuring muscle reflexes (e.g., a bulbocavernosus reflex) as a tool for identifying/diagnosing dysfunctions (e.g., spinal cord abnormalities, bladder voiding dysfunction, and sexual organ dysfunction) non-invasively by using mechanical stimulation. The system and method includes a probe having a predetermined patient contacting portion, wherein when the contacting portion is moved into contact with a particular area of the patient (e.g., the patient's genitals), the contact induces a muscle reflex. The probe detects the pressure resulting from the contacting portion being abruptly and forcibly brought into contact with the particular area. Such detection is used to electronically initiate capture of electrical responses from a plurality of electrodes placed on the patient's skin in proximity to the particular area. Such electrical responses are processed to determine characteristics of the patient's reflexes of one or more muscles adjacent to the electrodes.

Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic. Methods for use of this apparatus are also described.

An apparatus for neural block determination is provided including processing circuitry configured to receive muscle movement measurements, analyze the muscle movement measurements in a frequency domain, and determine an effectiveness of an anesthetic based on the analysis of the muscle movement measurements in the frequency domain.

Methods and apparatus for adapting a control mapping associating sensor signals with control signals for controlling an operation of a device. The method comprises obtaining first state information for an operation of the device, providing the first state information as input to an intention model associated with an operation of the device and obtaining corresponding first intention model output, providing a plurality of neuromuscular signals recorded from a user and/or signals derived from the neuromuscular signals as inputs to a first control mapping and obtaining corresponding first control mapping output, and updating the first control mapping using the inputs provided to the first control mapping and the first intention model output to obtain a second control mapping.

In an example embodiment, this disclosure provides a non-transitive computer-readable medium on which are stored instructions executable by a processor, the instructions which, when executed by the processor, cause the processor to perform a method. The method includes computing, based on test performance data of a user, at least one of a performance variable characterizing cognitive functioning and a performance variable characterizing neuromotor functioning. For each of the at least one performance variable, a respective score can be computed based on the respective performance variable and based on a set of performance metrics. The method can also include outputting, via an output device, the at least one computed score.

Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic. Methods for use of this apparatus are also described.

An ocular micro tremor (OMT) sensor, system and method for measuring micromovements of an individual's eyeball having an amplitude of 40 micrometers or less to provide a variable voltage biosignal for measuring the individual's brain stem activity. The OMT sensor includes a flexible piezo-active sensing element mounted at the individual's closed or opened eyelid so as to be deflected by the micromovements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the piezo-active sensing element to an OMT amplifier located on the individual's skin where the biosignal is amplified. The OMT amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician.

Embodiments relate to devices, systems and methods for monitoring neuromuscular blockage. In an embodiment, a neuromuscular blockage monitoring system comprises a patch device comprising a unitary patch body, at least two electrodes and at least one sensor, the at least one sensor arranged between the at least two electrodes on the unitary patch body; and a stimulator device operatively coupled to the patch device and configured to provide at least one electrical signal to the at least two electrodes to stimulate a muscle motor point and to receive a signal from the at least one sensor related to a result of the stimulation of the muscle motor point.

An ocular micro tremor (OMT) sensor, system and method for measuring micromovements of an individual's eyeball having an amplitude of 40 micrometers or less to provide a variable voltage biosignal for measuring the individual's brain stem activity. The OMT sensor includes a flexible piezo-active sensing element mounted at the individual's closed or opened eyelid so as to be deflected by the micromovements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the piezo-active sensing element to an OMT amplifier located on the individual's skin where the biosignal is amplified. The OMT amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician.

In an example embodiment, this disclosure provides a computer system that includes a processor configured to compute, based on test performance data of a user, at least one performance variable characterizing balance and postural stability, and at least one performance variable characterizing vestibulo-ocular reflex (VOR). For each performance variable, processor can compute a respective score based on the respective performance variable and based on a set of performance metrics. The at least one computed score can be output via an output device.