A biosensor including light emitting elements and a light receiving element disposed on a principal surface of a wiring board; a light shielding portion disposed between a light-emitting-element sealing portion and a light-receiving-element sealing portion; a base medium having light transmitting properties, disposed in parallel with the wiring board with the light shielding portion therebetween; an adhesion layer having light transmitting properties that bonds the base medium with the light-emitting-element sealing portion, the light-receiving-element sealing portion, and the light shielding portion; and a first electrocardiograph electrode attached to a principal surface of the base medium. Both end portions of the adhesion layer and both end portions of the base medium are disposed such that they overlap neither of the light-receiving-element sealing portion nor the light-emitting-element sealing portion when viewed from a direction normal to the principal surface of the wiring board.

A device for determining a physiological property of a body includes an insulating support having a compliant contact surface with a conductive element to contact the body. A mounting fixture disposed over a mounting surface of the support removably holds a rigid sensor spaced apart from the body and coupled to the conductive element to determine the physiological property via that element. A method for enabling a physiological parameter to be measured without direct contact between an active device and the body includes arranging a conductive element over an inner surface of an insulating circumferential band. A sensor with the active device is attached to the exterior of the band and thus coupled to the element. A system includes the sensor having a mounting connector, and sensor carriers with respective supports, mounting fixtures, and conductive elements. The sensor mounted on a carrier determines the property via the respective conductive element.

The present invention provides an improved orthodontic bracket with integrated piezosensor chip determining even the slightest change in initial installation setup of orthodontic bracket system and further notifying the subscriber electronically comprising of orthodontic bracket, for holding the tooth; at least one wire, for connecting the orthodontic brackets; and at least one sensor chip placed on the bracket and/or on the wire, wherein, at least one pulse oximeter is installed at the periphery of the bracket base to ensure force applied are within biological limits; the invention provides a detachable wireless frequency transmitter to be placed on the bracket of tie-wing to permit clinical recycling of the bracket; and optionally allowing a handheld laser scanner/photospectrometer to measure the frictional coefficient between the archwire and bracket to determine exact amount of force required for tooth retraction; to determine the bonding technique for detecting voids in adhesive; and to determine the distance between forces applied and center of mass of the tooth.

The present disclosure relates generally to devices, systems, and methods for diagnosis and treatment via laser-treated skin and, more particularly, to devices, systems, and methods for inducing leakage or rupture of one or more blood vessels comprising the dermis for various diagnostic and therapeutic applications. Other aspects of the present disclosure can include methods for detecting one or more target analytes in a dermis of a subject, methods for facilitating skin-to-blood delivery of agent in a subject, and methods for collecting a fluid sample from the dermis of a subject.

A wireless patient monitoring device can be fully functional stand-alone patient monitoring device capable of various physiological measurements. The patient monitoring device is small and light enough to be comfortably worn on the patient, such as on the patient's wrist or around the neck. The patient monitoring device can have a monitor instrument removably engaging a disposable base. The base can have outlets for connecting to an acoustic respiration sensor and an oximeter sensor. The patient monitoring device can have pogo pin connectors connecting the monitor instrument and the disposable base so that the monitor instrument can receive sensor data from the sensors connected to the disposable base.

Physiological signal processing systems include a photoplethysmograph (PPG) sensor that is configured to generate a physiological waveform, and an inertial sensor that is configured to generate a motion signal. A physiological metric extractor is configured to extract a physiological metric from the physiological waveform that is generated by the PPG sensor. The physiological metric extractor includes an averager that has an impulse response that is responsive to the strength of the motion signal. Related methods are also described.

A system includes at least one earpiece, wherein each earpiece comprises an earpiece housing, an optical source operatively connected to the earpiece housing, wherein the optical source is configured to emit light toward an ear surface, an optical sensor operatively connected to the earpiece housing, wherein the optical sensor is configured to receive reflected light from the ear surface, and at least one processor disposed within at least one earpiece and operatively connected to the optical source and the optical sensor, wherein the at least one processor is configured to separate the pulse oximetry signals from the audio signals in the reflected light detected by the optical sensor.

An oximeter probe includes a probe unit or a base unit and a probe tip where the probe tip has a number of sources and detectors that can be accessed individually or in differing combinations for measuring tissue oxygen saturation at different tissue depth in tissue. A processor of the oximeter probe controls a multiplexer that is coupled to the detectors for selectively collecting measurement information from the detectors via the multiplexer. The oximeter probe is user programmable via one or more input devices on the oximeter probe for selecting the particular sources and detectors to collect measurement information from by the processor.

A sensing device includes a substrate, two chips, and a shielding structure. The two chips are respectively defined as an emitting chip and a receiving chip. The emitting chip can emit a sensing light beam, the receiving chip can receive the sensing light beam, and the two chips are fixed in position on the substrate at intervals. At least one of the chips is electrically connected to the substrate through at least one wire, and a position where the wire is connected to the substrate is located between the two chips. The shielding structure is formed on the substrate. The shielding structure is located between the two chips, and the shielding structure covers the wire and a portion of the chip connected to the wire. Compared with the conventional photo-plethysmography sensor, the sensing device has the advantage of a smaller size.

A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.