A cap and seal system for a liquid medicament container. The system comprises a cap formed from a substantially rigid material, and has a retention component integrally formed therewith. A seal is formed from a material which is less hard than the cap and positioned within the cap such that, when the retaining component retains the cap on a container in use the seal is positioned such that it forms a fluid tight seal between the cap and the container. A recess is formed in the seal through which a liquid outlet channel can pass in use to access the contents of the container via the cap and the seal.

The present disclosure is a blood collection assembly that has a needle assembly fixedly coupled to a finger-activated actuator and tubing and the needle assembly has a needle. Further, the blood collection assembly has a hub that houses the needle assembly and the hub has a channel in a top surface of the hub. Additionally, the channel slidably engages the finger-activated actuator such that when the finger-activated actuator is moved from a distal end of the hub to a proximal end of the hub the needle retracts within the hub.

A device (100) having a proximal end (20) and end a distal end (40) for withdrawal of a liquid sample, fractionation, and separation of one or more fractions comprising: a piston assembly (300) comprising a piston (302) dismountably attached at its proximal end (20) to an actuating rod (350); a container (200) having a body (202) disposed with a cylindrical chamber (204) for slidable movement of the piston (302) therein; wherein the cylindrical chamber (204) is provided at the distal end (40) with a resealable septum (410) for co-operation with a puncture needle assembly (600) for withdrawal of the liquid sample, an at the proximal end (20) with a stop member (206), which stop member (206) limits movement of the piston (300) in a proximal direction, wherein the container body (202) is dimensioned to fit inside a centrifuge rotor, and is configured for breakability into two parts at a temperature of 0 deg C. or lower at a breakable zone (210).

In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.

Systems and methods are provided for sample collection from one or more subjects using mobile sample collection devices.

An intravenous catheter device may include a guidewire for actively repositioning the catheter tip. A guidewire assembly may be configured to enable a clinician to actively reposition the catheter tip by moving proximal ends of segments of the guidewire. By repositioning the catheter tip, the guidewire assembly may facilitate the collection of a blood sample or the injection of a fluid through the catheter even in instances when the catheter tip has become occluded.

A catheter extension set may include a housing, which may include a distal end, a proximal end, and a lumen. The catheter extension set may include a distal connector coupled to the distal end of the housing and configured to couple to a catheter assembly. The catheter extension set may include a handle, an advancement element, and an instrument. The instrument may extend through a U-shaped channel of the advancement element and may include a fixed first end and a second end. A translation feature may be disposed between the handle and the housing and within a pocket of the advancement element such that in response to distal movement of the handle a first distance, the advancement element moves distally within the lumen the first distance and the second end of the instrument advances distally a second distance. The second distance may be at least twice the first distance.

A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.

The invention relates to a detection apparatus and a method for detecting and manipulating a blood vessel under the skin of part of the body of a patient, which comprises a treatment chamber for accommodating the body part, a data processing control device, a vascular structure measuring device for detecting the position and/or dimensions of vascular structure data of the blood vessel in the treatment chamber by measurement, a vascular manipulation device for changing the position and/or dimension of the blood vessel, wherein the control device is designed to control the vascular manipulation device as a function of the vascular structure data.

A medical device is configured to be attached to a part of a circulation circuit of an extracorporeal circulation device and to be inserted with an insertion member for performing a test related to blood clotting, and includes a storage portion configured to store a blood, and a main body portion configured to drop the blood stored in the storage portion onto the insertion member. The stored blood is used as samples for testing and monitoring of blood conditions (e.g., clotting) during extracorporeal circulation.