An independent blood filter device depends on flow geometry to deliver blood serum or plasma free of detrimental levels of hemoglobin. It depends critically on an upstream flow rate or pressure differential limiting control element or device that limits the rate of change of pressure differential across the filter element. Pre-evacuated versions can be used to simultaneously draw blood from a living being and provide pressure differential across the filter element between an evacuated collector and a supply end open to atmosphere. A unit pressurized by hand motion employs the external shape of a partially filled blood collection tube as a piston to produce pressure in advance of the control element or device to create the pressure differential across the filter element to a collector vented to atmosphere. The control element or device is disclosed in numerous forms, including specially sized flow constrictions and compliant arrangements.

Various embodiments pertain to syringes having needles that automatically retract, and including syringe assemblies in which there is a means for damping any impact of the retracting needle, slowing the retracting needle, dissipating the kinetic energy of the needle, or the like, so as to lessen any jolt or disturbance experienced by the user.

A syringe apparatus (10) is provided which comprises a syringe portion having a syringe (12) or holder (24) adapted to receive a syringe (12) therein, the syringe portion having a rear grip (38) for seating in or against a user's hand and a front grip (40) formed at or adjacent to a tip end (22) of the syringe portion; and a movable member (30) engagable with a plunger (16) of the said syringe (12), the movable member (30) having a finger grip (32) at or adjacent to a tip end (22) thereof, the movable member (30) being engaged with the syringe portion and configured to move relative to the rear grip when a user applies a force at the finger grip (32); wherein the front and rear grips (40, 38) are formed as lateral projections (40a, 40b; 38a, 38b) with respect to the movable member (30).

A bodily fluid collection system for collecting a bodily fluid from a patient, and a bodily fluid transfer system for transferring collected bodily fluid to a second collection device. A collection adapter has a connection port configured to securely connect with a hub of a syringe, and a collection interface opposite the connection port creates a fluid conduit to the barrel via the connection port and an inlet of the hub. A proximal adapter is connected to a proximal end of the fluid channel from the patient, and configured to removably interact with the collection interface of the collection adapter to connect the proximal end of the fluid channel to the barrel via the fluid conduit and inlet to the barrel to allow conveyance into the barrel of the at least some of the sampling portion of the sample of bodily fluid. The proximal adapter can be removed to allow access to any bodily fluid collected by the syringe.

Apparatus and methods for a single, handheld device that provides for both insertion of a catheter and collection of a fluid. Some embodiments further include a needle that assists in the insertion of the catheter into a blood vessel, and which includes a retraction feature that protects the user from an accidental needle stick when the device is ready for disposal. Still further embodiments include a protective cover that prevents a user from accidentally being stuck by a second needle used for the introduction of the patient's blood into a collection device.

A sample collection container configured to be removably mounted to a blood collection device includes: a housing having a flow channel extending through the housing having an inlet and an outlet and a container body removably connected to the housing. The container body includes an open top, a closed bottom, and an interior wall extending between the top and the bottom defining a collection cavity. When the housing is connected to the container body, the outlet of the flow channel is in fluid communication with the collection cavity. The sample collection container also includes at least one additive dispersing object positioned to be contacted by blood flowing from the blood collection device through the flow channel and/or into the collection cavity. The at least one additive dispersing object includes an additive composition to be mixed with the blood passing along the flow channel and into the collection cavity.

A flow restriction device may include a male luer connector portion, a female luer connector portion disposed proximally to the male luer connector portion, and a body portion extending between the male and female luer portions, and integrally formed with the male and female luer portions to form a single monolithic piece. The male luer connector portion may have an internal surface defining a lumen thereof, and the female luer connector portion may have an internal surface defining a lumen fluidly connected to the lumen of the male luer connector portion. The body portion may have a recess extending longitudinally therethrough and fluidly communicated with the lumens of the male luer portion and the female luer portion. The recess may define a micro-channel along which fluid flows from the male luer connector portion into the fluid collection device via the female luer connector portion.

A flow restriction device may include a distal end configured to couple to a catheter assembly, a proximal end configured to couple to a fluid collection device, and a body extending from the proximal end to the distal end. The body may include an outer surface and an inner surface defining a lumen of the body. The flow restriction device may further include a fluid pathway disposed between the distal end and the proximal end when the outer surface is coupled within a mating luer. The fluid pathway may include a non-linear portion on at least a portion of the outer surface along which a fluid flows from the distal end into the fluid collection device.

The present disclosure provides a body-insertion device for a body, which comprises a first moving unit for moving an image acquisition unit; an insertion unit; and a second moving unit for moving the insertion unit. The first moving unit comprises at least one of a 1-1 module for moving the image acquisition unit in a 1-1 direction, a 1-2 module for moving the image acquisition unit in a 1-2 direction, and a 1-3 module for moving the image acquisition unit in a 1-3 direction. The second moving unit comprises at least one of a 2-1 module for moving the insertion unit in a 2-1 direction, a 2-2 module for moving the insertion unit in a 2-2 direction, and a 2-3 module for moving the insertion unit in a 2-3 direction.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.