The present disclosure provides an electroencephalogram electrode cap, including: a stretchable covering body; an electrode array; and a fixing seat. The fixing seat includes a fixing structure. The fixing seat is mounted on the stretchable covering body through the fixing structure. The fixing seat further includes a hollow chamber for accommodating conductive medium or conductive medium preform. The electrode array includes plug ends, a plurality of electrode sensing units and a plurality of conductive traces. One end of the conductive trace is connected with the electrode sensing unit, and another end of the conductive trace is connected with the plug end. The electrode sensing unit is connected with the fixing seat.

An ECG electrode includes a substrate and one or more holes. The substrate includes on one side an electrolyte gel for contacting a patients skin and an adhesive. The one or more holes perforate the substrate and the adhesive to increase the adhesion between the patients skin and the substrate. The one or more holes can have a circular shape, rectangular shape, crescent shape, polygonal shape, elliptical shape, diamond shape, star shape, or triangular shape. A method for manufacturing an ECG electrode includes assembling a substrate that includes on one side an electrolyte gel for contacting a patients skin and an adhesive and creating one or more holes in the substrate and the adhesive that increase the adhesion between the skin and the substrate. The one or more holes are created using a laser or a drill.

An ECG electrode includes a substrate and one or more holes. The substrate includes on one side an electrolyte gel for contacting a patients skin and an adhesive. The one or more holes perforate the substrate and the adhesive to increase the adhesion between the patients skin and the substrate. The one or more holes can have a circular shape, rectangular shape, crescent shape, polygonal shape, elliptical shape, diamond shape, star shape, or triangular shape. A method for manufacturing an ECG electrode includes assembling a substrate that includes on one side an electrolyte gel for contacting a patients skin and an adhesive and creating one or more holes in the substrate and the adhesive that increase the adhesion between the skin and the substrate. The one or more holes are created using a laser or a drill.

A wearable device and methods for providing a wearable device are disclosed. In a first aspect, the wearable device comprises at least one power source, one computer controller and a plurality of instruments that when worn on a user access physiological data from at least the user axilla. The wearable device monitors one or more or a combination of body temperature, pulse, R-R interval, respiration rate, pulse ox (Sp02), sleep, movement included fall detection. The device stores, processes and communicates collected or processed data to an external computer system. A software system provides summary information, reporting and alarms based on data collected by the one or more instruments.

A wearable device and methods for providing a wearable device are disclosed. In a first aspect, the wearable device comprises at least one power source, one computer controller and a plurality of instruments that when worn on a user access physiological data from at least the user axilla. The wearable device monitors one or more or a combination of body temperature, pulse, R-R interval, respiration rate, pulse ox (Sp02), sleep, movement included fall detection. The device stores, processes and communicates collected or processed data to an external computer system. A software system provides summary information, reporting and alarms based on data collected by the one or more instruments.

An electrode patch for use with an external medical device, the electrode patch comprising: a first surface configured to be attached to a skin of a patient monitored by the external medical device, and an indicating mechanism disposed on the electrode patch and configured to indicate an end of a predetermined lifespan of the electrode patch.

A system for performing measurements on a biological subject, the system including: at least one substrate including a plurality of plate microstructures configured to breach a stratum corneum of the subject; at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure response signals from the at least one microstructure; and, one or more electronic processing devices configured to: determine measured response signals; and, at least one of: provide an output based on measured response signals; perform an analysis at least in part using the measured response signals; and, store data at least partially indicative of the measured response signals.

An electrode patch for use with an external medical device, the electrode patch comprising: a first surface configured to be attached to a skin of a patient monitored by the external medical device, and an indicating mechanism disposed on the electrode patch and configured to indicate an end of a predetermined lifespan of the electrode patch.

A subcutaneous sensor for use with a continuous glucose monitor includes a reference electrode, a working electrode, and a composition for releasing nitric oxide (NO). The reference electrode includes a reference substrate and an ion limiting layer over the reference substrate. The working electrode includes a conductive substrate, an interference layer over the conductive substrate, an enzyme layer over the interference layer, and a glucose limiting layer. The enzyme layer has an enzyme for reacting with in-vivo glucose in body fluid of a patient. The glucose limiting layer is over the enzyme layer and limits an amount of the in-vivo glucose from the body fluid of the patient that passes to the enzyme layer. The composition for releasing nitric oxide (NO) includes a NO release compound, a hydrophilic material and a hydrophobic material. The composition is on the reference electrode.

A subcutaneous sensor for use with a continuous glucose monitor includes a reference electrode, a working electrode, and a composition for releasing nitric oxide (NO). The reference electrode includes a reference substrate and an ion limiting layer over the reference substrate. The working electrode includes a conductive substrate, an interference layer over the conductive substrate, an enzyme layer over the interference layer, and a glucose limiting layer. The enzyme layer has an enzyme for reacting with in-vivo glucose in body fluid of a patient. The glucose limiting layer is over the enzyme layer and limits an amount of the in-vivo glucose from the body fluid of the patient that passes to the enzyme layer. The composition for releasing nitric oxide (NO) includes a NO release compound, a hydrophilic material and a hydrophobic material. The composition is on the reference electrode.