A medical lead with at least a distal portion thereof implantable in the brain of a patient is described, together with methods and systems for using the lead. The lead is provided with at least two sensing modalities (e.g., two or more sensing modalities for measurements of field potential measurements, neuronal single unit activity, neuronal multi unit activity, optical blood volume, optical blood oxygenation, voltammetry and rheoencephalography). Acquisition of measurements and the lead components and other components for accomplishing a measurement in each modality are also described as are various applications for the multimodal brain sensing lead.

A medical lead with at least a distal portion thereof implantable in the brain of a patient is described, together with methods and systems for using the lead. The lead is provided with at least two sensing modalities (e.g., two or more sensing modalities for measurements of field potential measurements, neuronal single unit activity, neuronal multi unit activity, optical blood volume, optical blood oxygenation, voltammetry and rheoencephalography). Acquisition of measurements and the lead components and other components for accomplishing a measurement in each modality are also described as are various applications for the multimodal brain sensing lead.

Some systems, devices and methods detailed herein provide a system for use in determining metrics of a subject. The system can provide, as an output, a function-metric value determined based on a defined relationship between physiological measures and a chronological age.

A dry electrode and a physiological multi-parameter monitoring equipment are disclosed. The waterproof dry electrode comprises an encapsulation, extraction electrode and a contact surface layer, wherein the extraction electrode and the contact surface layer are connected with each other and disposed in the encapsulation; the contact surface layer comprises an exposed part and an embedded part encapsulation; the encapsulation comprises flexible silica gel and hard plastic portion, the embedded part being embedded into the hard plastic portion, and the hard plastic portion being packaged in the flexible silica gel. Through the above arrangement in the present invention, the dry electrode can reach a waterproof grade of IPX7, which is higher than living waterproof grade of an ordinary dry electrode. The PMPME can be a patch-type acquisition and monitoring equipment which is convenient for long time wearing and physiological multi-parameter monitoring, with excellent sealing and waterproofness, and the electrode is reusable.

A dry electrode and a physiological multi-parameter monitoring equipment are disclosed. The waterproof dry electrode comprises an encapsulation, extraction electrode and a contact surface layer, wherein the extraction electrode and the contact surface layer are connected with each other and disposed in the encapsulation; the contact surface layer comprises an exposed part and an embedded part encapsulation; the encapsulation comprises flexible silica gel and hard plastic portion, the embedded part being embedded into the hard plastic portion, and the hard plastic portion being packaged in the flexible silica gel. Through the above arrangement in the present invention, the dry electrode can reach a waterproof grade of IPX7, which is higher than living waterproof grade of an ordinary dry electrode. The PMPME can be a patch-type acquisition and monitoring equipment which is convenient for long time wearing and physiological multi-parameter monitoring, with excellent sealing and waterproofness, and the electrode is reusable.

This document discusses, among other things, systems and methods for managing pain of a subject. A system includes one or more physiological sensors configured to sense a physiological signal indicative of patient brain activity. The physiological signals may include an electroencephalography signal, a magnetoencephalography signal, or a brain-evoked potential. The system may extract from the brain activity signal one or more signal metrics indicative of strength or pattern of brain electromagnetic activity associated with pain, and generate a pain score using the one or more signal metrics. The pain score can be output to a patient or a process. The system may select an electrode configuration for pain-relief electrostimulation based on the pain score, and deliver a closed-loop pain therapy according to the selected electrode configuration.

This document discusses, among other things, systems and methods for managing pain of a subject. A system includes one or more physiological sensors configured to sense a physiological signal indicative of patient brain activity. The physiological signals may include an electroencephalography signal, a magnetoencephalography signal, or a brain-evoked potential. The system may extract from the brain activity signal one or more signal metrics indicative of strength or pattern of brain electromagnetic activity associated with pain, and generate a pain score using the one or more signal metrics. The pain score can be output to a patient or a process. The system may select an electrode configuration for pain-relief electrostimulation based on the pain score, and deliver a closed-loop pain therapy according to the selected electrode configuration.

There are described headphones comprising earcups to be placed about ears of a user, with a headband linking the earcups and to be extending above a head of the user. A flexible band distinct from the headband is secured below the headband for contact with the head of the user. Removable headband sensors are embedded in the flexible band and have a portion thereof protruding downwardly from the flexible band to reach the scalp. The flexible band has a flexibility which makes the flexible band deform under the weight of the earcups to conform with the head of the user to ensure high quality contact between the headband electrodes and the scalp. There are further provided earcup electrodes on the earcups for contact with a region on or behind an ear of the user. Signals from the electrodes can be used for different purposes such as concentration monitoring and feedback.

There are described headphones comprising earcups to be placed about ears of a user, with a headband linking the earcups and to be extending above a head of the user. A flexible band distinct from the headband is secured below the headband for contact with the head of the user. Removable headband sensors are embedded in the flexible band and have a portion thereof protruding downwardly from the flexible band to reach the scalp. The flexible band has a flexibility which makes the flexible band deform under the weight of the earcups to conform with the head of the user to ensure high quality contact between the headband electrodes and the scalp. There are further provided earcup electrodes on the earcups for contact with a region on or behind an ear of the user. Signals from the electrodes can be used for different purposes such as concentration monitoring and feedback.

A group association system attempts to identify if an individual is “gifted” in any particular area. A group association system is based on brainwave response to stimulation is disclosed. The system including a brainwave stimuli device which provides stimuli to groups of highly skilled, general skilled, and a general population groups, as test stimuli for determination of group association. A brainwave collection device collects brainwaves of individuals, with the brainwave collection device storing collected brainwaves in a brainwave database. A brainwave processing device analyzes brainwaves received from the brainwave database. A brainwave analysis device uses analyst screens, artificial intelligence or machine learning to analyze the brainwaves create at least one signature development module for determination of similar brainwaves related to different individuals' responses to the same stimuli. In addition, at least one signature development module determines which individuals have the same or similar brainwave responses to the same test stimuli.