A computer-implemented method for generating an annotated photoplethysmography signal, includes: recording an electrocardiogram or ECG signal; recording a photoplethysmography or PPG signal, semi-synchronously with the recording of the ECG signal; annotating segments in the ECG signal either algorithm-based or expert-based; time-aligning the PPG signal and the ECG signal; detecting ECG beats in the ECG signal; detecting PPG beats in the PPG signal; pairing the ECG beats onto the PPG beats; deriving annotations for PPG signal segments based on the nature of the ECG segment annotations and on how the ECG beats can be paired with the PPG beats; and annotating the PPG signal segments using the annotations, thereby generating the annotated PPG signal.

Techniques for switching an implantable medical device (IMD) from a first mode to a second mode in relation to signals obtained from internal sensors are described. The internal sensors may include a temperature sensor and a biosensor. In some examples, processing circuitry of the IMD may make a first preliminary determination that the IMD is implanted based on a first signal from the temperature sensor. In response to the first preliminary determination being that the IMD is implanted, the processing circuitry may make a second preliminary determination that the IMD is implanted based on a second signal from the biosensor. The processing circuitry may switch the IMD from a first mode to a second mode based on both the first preliminary determination and the second preliminary determination being that the IMD is implanted.

A device and method for determining the severity of sleep apnea using electroencephalography and electromyography. The device includes a headgear having a head pan sized to cover the head of a patient, at least at the locations where the measuring points C3 and C4 of the electroencephalography are situated, and a chin part, and wherein the head part has two electrodes for sensing EEG-signals of the electroencephalography at the electroencephalography points C3 and C4, and the chin part has at least one electrode for sensing the EMG-signal of the electromyography in the chin.

An apparatus comprising: at least one electrode, having a first potential, arranged to sense a biosignal; a conductive shield provided over the at least one electrode where the conductive shield is configured to be driven to a second potential wherein the second potential is equivalent to the first potential plus a multiple of an inverted common mode voltage; and wherein the conductive shield is coupled to a drain to enable triboelectric charges to be dissipated.

A pacemaker system includes a drive-sense circuit (DSC) operably coupled to a pacemaker lead. The DSC generates a pace signal including electrical impulses based on a reference signal. The DSC provides the pace signal via the pacemaker lead to an electrically responsive portion of a cardiac conductive system of a subject to facilitate cardiac operation of a cardiovascular system of the subject. The DSC senses, via the pacemaker lead, cardiac electrical activity of the cardiovascular system of the subject that is generated in response to the pace signal and electrically coupled into the pacemaker lead and generates a digital signal that is representative of the cardiac electrical activity of the cardiovascular system of the subject that is sensed via the pacemaker lead. The DSC provides digital information to one or more processing modules that includes and/or is coupled to memory and that provide the reference signal to the DSC.

Systems, devices, and methods for electroporation ablation therapy are disclosed, with a protection device for isolating electronic circuitry, devices, and/or other components from a set of electrodes during a cardiac ablation procedure. A system can include a first set of electrodes disposable near cardiac tissue of a heart and a second set of electrodes disposable in contact with patient anatomy. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the first set of electrodes and configured to repeatedly deliver the pulse waveform to the first set of electrodes. The system can further include a protection device configured to selectively couple and decouple an electronic device to the second set of electrodes.

In an embodiment, there is provided an apparatus. The apparatus includes an analog front end for biosignal acquisition. The analog front end includes an instrumentation amplifier and a reconfigurable filter. The instrumentation amplifier is configured to receive a biosignal and includes a super class-AB output stage. The reconfigurable filter is coupled to an output of the instrumentation amplifier. The reconfigurable filter has a selectable gain and an adjustable bandwidth. The bandwidth is adjusted based, at least in part, on a duty cycle of a clock signal.

In an embodiment, there is provided an apparatus. The apparatus includes an analog front end for biosignal acquisition. The analog front end includes an instrumentation amplifier and a reconfigurable filter. The instrumentation amplifier is configured to receive a biosignal and includes a super class-AB output stage. The reconfigurable filter is coupled to an output of the instrumentation amplifier. The reconfigurable filter has a selectable gain and an adjustable bandwidth. The bandwidth is adjusted based, at least in part, on a duty cycle of a clock signal.

A computer implemented method and system for detecting an arrhythmia are provided. The method is under control of one or more processors configured with executable instructions. The method obtains far field cardiac activity (CA) signals sensed at electrodes located remote from a heart over a period of time and applies a feature attenuation filter to the CA signals to form modified CA signals. The feature attenuation filter reduces potential T-waves as a feature not of interest. The method calculates a duty cycle (DC) characteristic of the modified CA signals with respect to duty cycle boundaries and detects an arrhythmia based on the DC characteristic.

A computer implemented method and system for detecting an arrhythmia are provided. The method is under control of one or more processors configured with executable instructions. The method obtains far field cardiac activity (CA) signals sensed at electrodes located remote from a heart over a period of time and applies a feature attenuation filter to the CA signals to form modified CA signals. The feature attenuation filter reduces potential T-waves as a feature not of interest. The method calculates a duty cycle (DC) characteristic of the modified CA signals with respect to duty cycle boundaries and detects an arrhythmia based on the DC characteristic.