The invention relates to a diagnostic system for the simultaneous long-term registration of heart rate variability as well as the pressure value and/or the impedance and, if so desired, further measured values of a patient with a measuring probe system suitable for deriving data for electrocardiogram generation, a catheter for insertion into the esophagus of the patient, the catheter being provided with several measuring probes each for pressure determination and/or for impedance measurement, and, if required, further measuring probes for determining further measured values, a recording apparatus having a voltage source and a plurality of channels for the registration and recording of the measurement data originating from the measuring probes, at least one memory for time-dependent storage of the measurement data and means for data transmission from the measuring probes to the recording apparatus for use in the diagnosis of motility disorders influenced by the autonomic nervous system and the use of this system in the differential diagnosis of motility disorders.

A method for reducing discomfort when viewing virtual reality (VR) content for use in head mounted displays (HMDs). The method includes accessing a model that identifies a plurality of learned patterns associated with the generation of corresponding baseline VR content that is likely to cause discomfort. The method includes processing a first application to generate data associated with simulated user interactions with first VR content of the first application. The method includes comparing the data to the model to identify a pattern in the data matching at least one of the learned patterns, such that the identified pattern is likely to cause discomfort. The method includes identifying a zone in the first application corresponding to identified pattern. The method includes applying a discomfort reduction filter effect within the zone for purposes of reducing potential discomfort in a user.

A method and system for monitoring a biomedical signal employ a sensor module configured to output a continuous electrical signal by sensing the biomedical signal, a memory configured to store reference data, a transmitter configured to transmit output data via a wireless channel, and a data processing unit configured to determine whether to transmit input data via the transmitter as the output data, based on the input data, which is generated from the continuous electrical signal, and the reference data.

A gastro-electrical activity mapping system and method may comprise a catheter insertable through a natural orifice into the gastro-intestinal (GI) tract and comprising an array of electrodes for contacting an interior surface of a section of the GI tract to detect electrical potentials at multiple electrodes, and comprises a signal analysis and mapping system arranged to receive and process electrical signals from multiple electrodes of the array and spatially map GI smooth muscle electrical activity as an activation time map, a velocity map, or an amplitude map, which may be in the form of contour plots and may be mapped on an anatomical computer model of at least the section of the GI tract and may be animated.

A physiological monitoring device is provided. The physiological monitoring device includes a physiological sensor, a quality estimator, and a feature extractor. The physiological sensor is configured to sense a physiological feature to generate a bio-signal. The quality estimator estimates quality of the bio-signal. The feature extractor receives the bio-signal and performs a predetermined operation to the bio-signal to obtain feature data. The amount of computation induced by the predetermined operation tier the feature extractor is changed according to the estimated quality of the bio-signal.

Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.

Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.

An esophagus PH-myoelectricity combined electrode catheter, comprising a catheter body (9), wires for PH electrodes (11) and wires for diaphragm EMG (12); two PH electrodes (1, 2), multipair diaphragm EMG electrodes (3, 4, 5, 6, 7) and a reference electrode (8) are attached on the surface of the catheter body (9); the two PH electrodes (1, 2) are respectively located at the distal end and the middle part of the catheter (9), multipair diaphragm EMG recording electrodes (3, 4, 5, 6, 7) are located between the two PH electrodes (1, 2), and the reference electrode for diaphragm EMG recording (8) is located at the proximal end of the PH electrode (2) at the middle part; both the PH electrodes (1, 2) are connected to the PH wire (11) inside the catheter (9), PH signal extension wire (11) is further connected to PH processor joint (13); the reference electrode (8) and the electrodes for recording diaphragm EMG (3, 4, 5, 6, 7) are connected to the wires (12) inside the catheter (9), and the diaphragm EMG signal extension wires (12) are connected to socket for bio-amplifier (14). The esophagus PH-myoelectricity combined electrode catheter can easily and accurately position PH electrodes to stomach and esophagus to reduce discomfort. With this technique gastroesophageal reflux and diaphragm function could be assessed and the potential cause of gastroesophageal reflux could be determined.

An esophagus PH-myoelectricity combined electrode catheter, comprising a catheter body (9), wires for PH electrodes (11) and wires for diaphragm EMG (12); two PH electrodes (1, 2), multipair diaphragm EMG electrodes (3, 4, 5, 6, 7) and a reference electrode (8) are attached on the surface of the catheter body (9); the two PH electrodes (1, 2) are respectively located at the distal end and the middle part of the catheter (9), multipair diaphragm EMG recording electrodes (3, 4, 5, 6, 7) are located between the two PH electrodes (1, 2), and the reference electrode for diaphragm EMG recording (8) is located at the proximal end of the PH electrode (2) at the middle part; both the PH electrodes (1, 2) are connected to the PH wire (11) inside the catheter (9), PH signal extension wire (11) is further connected to PH processor joint (13); the reference electrode (8) and the electrodes for recording diaphragm EMG (3, 4, 5, 6, 7) are connected to the wires (12) inside the catheter (9), and the diaphragm EMG signal extension wires (12) are connected to socket for bio-amplifier (14). The esophagus PH-myoelectricity combined electrode catheter can easily and accurately position PH electrodes to stomach and esophagus to reduce discomfort. With this technique gastroesophageal reflux and diaphragm function could be assessed and the potential cause of gastroesophageal reflux could be determined.

The present disclosure discuses systems and methods for detecting and recording bioelectric signals, and specifically bioelectrical signals generated by abdominal organs, such as the uterus. The disclosure discusses area electrodes and arrays of area electrodes. The area electrodes are defined in a metal layer and include an inner and outer diameter. The area electrodes are configured to detect electrical signals generated substantially perpendicular to a surface of the area electrode while rejecting electrical signals generated substantially parallel to the surface of the area electrode.