Summary The claimed medicament relates to medicine, and it can be used to treat disordered functions of organs or tissues, as well as a wide range of diseases accompanied by disordering of the functions of organs or tissues. The claimed medicament contains the original drug substance or the released-active form of the drug substance treated with bioelectric potentials which have been taken reading from the respective organ or tissue with normal functioning. The pharmaceutical drug substance or the released-active drug substance treated with bioelectric potentials can further be undergo successive multiple dilutions in a solvent selected from the group comprising water and a mixture of water and. The method of obtaining the drug involves exposing the drug substance or the released-active form of the drug substance to bioelectric potentials taken reading from the organ or tissue with normal functioning, with a further, optional successive multiple dilutions in a solvent.

Summary The claimed medicament relates to medicine, and it can be used to treat disordered functions of organs or tissues, as well as a wide range of diseases accompanied by disordering of the functions of organs or tissues. The claimed medicament contains the original drug substance or the released-active form of the drug substance treated with bioelectric potentials which have been taken reading from the respective organ or tissue with normal functioning. The pharmaceutical drug substance or the released-active drug substance treated with bioelectric potentials can further be undergo successive multiple dilutions in a solvent selected from the group comprising water and a mixture of water and. The method of obtaining the drug involves exposing the drug substance or the released-active form of the drug substance to bioelectric potentials taken reading from the organ or tissue with normal functioning, with a further, optional successive multiple dilutions in a solvent.

Disclosed are devices, systems and methods for monitoring electrophysiological function from anatomical structures, including gastric slow-waves in high resolution electrogastrograms. In some aspects, a device includes an electrophysiological sensor structured to include an array of electrodes spatially arranged on a substrate and operable to acquire electrophysiological signals to obtain time-series data, the electrodes spaced about an anatomical structure on the subject's body with at least one electrode placed with reference to an anatomical landmark and other electrodes of the electrode array each placed at a spatial distance from another of the surface electrodes; and a data processing unit to process spatially resolved time-series data based on the electrophysiological signals to determine wave propagation parameters including direction and/or speed for each time point of interest of the acquired electrophysiological signals, in which the wave propagation parameters are associated with a physiological function of the anatomical structure of the subject's body.

Disclosed are devices, systems and methods for monitoring electrophysiological function from anatomical structures, including gastric slow-waves in high resolution electrogastrograms. In some aspects, a device includes an electrophysiological sensor structured to include an array of electrodes spatially arranged on a substrate and operable to acquire electrophysiological signals to obtain time-series data, the electrodes spaced about an anatomical structure on the subject's body with at least one electrode placed with reference to an anatomical landmark and other electrodes of the electrode array each placed at a spatial distance from another of the surface electrodes; and a data processing unit to process spatially resolved time-series data based on the electrophysiological signals to determine wave propagation parameters including direction and/or speed for each time point of interest of the acquired electrophysiological signals, in which the wave propagation parameters are associated with a physiological function of the anatomical structure of the subject's body.

Foley type catheter embodiments for sensing physiologic data from a urinary tract of a patient are disclosed. The system includes the catheter and a data processing apparatus and methods for sensing physiologic data from the urinary tract. Embodiments may also include a pressure sensor having a pressure interface at a distal end of the catheter, a pressure transducer at a proximal end, and a fluid column disposed between the pressure interface and transducer. When the distal end is residing in the bladder, the pressure transducer can transduce pressure impinging on it into a chronological pressure profile, which can be processed by the data processing apparatus into one or more distinct physiologic pressure profiles, for example, peritoneal pressure, respiratory rate, and cardiac rate. At a sufficiently high data-sampling rate, these physiologic data may further include relative pulmonary tidal volume, cardiac output, relative cardiac output, and absolute cardiac stroke volume.

Method and apparatus for monitoring eating behavior are disclosed. A wearable device including an imaging sensor, an electromyography (EMG) sensor, and a processing unit is configured to collect EMG data via the EMG sensor, transmit the EMG data to a computing device, receive a control signal to capture one or more images via the imaging sensor, capture, one or more images, and transmit the one or more images. A computing device is disclosed including a processor and a memory containing a machine learning model and computer program code that, when executed, performs an operation. The operation includes receiving EMG data, processing the EMG data as input to a trained machine learning model, transmitting the control signal to capture one or more images via the imaging sensor, receiving the one or more images, and determining nutritional content of the food or beverage using the one or more images.

A method including transcutaneously measuring motility patterns, in the colon of a recipient of an implantable neuromodulator, responsive to an electrical stimulus delivered by the implantable neuromodulator, and programming the implantable neuromodulator responsive to the measured motility patterns, wherein the method comprises adjusting at least one parameter of the implantable neuromodulator that defines the electrical stimulus that the implantable neuromodulator is configured to deliver to the recipient.

Methods, systems, and devices are disclosed for characterizing the gastrointestinal functions using non-invasive surface recordings from EGG. In one aspect, a system for non-invasively characterizing gastrointestinal functions is disclosed. The system includes electrodes configured to capture a gut electrophysiology recording; and a processor to estimate a frequency and an amplitude of the recording across time.

Devices and methods for detecting meal intake are disclosed herein. In some embodiments, one or more sensors can be used to detect or monitor physiological parameters of a user (e.g., heart rate, body movements, temperature, pH, impedance, gastric stretch, sound emissions, and the like). The outputs of the sensors can be received by a computer system configured to analyze the sensor data and make a determination as to whether meal intake has occurred or is presently occurring. The computer system's determination can be used to trigger, modulate, or otherwise control one or more therapeutic devices. Other types of devices can also be controlled using this determination, such as monitoring or logging devices.

The present invention is for a method and system for pain classification and monitoring optionally in a subject that is an awake, semi-awake or sedated.