A tremor-reduction system is provided that delivers electric current to a body region of a subject that is associated with a tremor. A computing device stores received data associated with a tremulous movement of the body region and determines measurements associated with the stored data. If a magnitude of the most recent tremulous movement is the same as or greater than magnitudes associated with prior tremulous movements, characteristics of a subsequent electric current to be applied to the body region may be adjusted.

A computer-implemented method for pelvic floor feedback. The method includes capturing a strength of action potentials via wireless sensors, the wireless sensors positioned proximate to a pelvic floor of a user. The method also includes transmitting the strength of the action potentials to a mobile device. The method also includes recording the strength of the action potentials on the mobile device.

A computer-implemented method for pelvic floor feedback. The method includes capturing a strength of action potentials via wireless sensors, the wireless sensors positioned proximate to a pelvic floor of a user. The method also includes transmitting the strength of the action potentials to a mobile device. The method also includes recording the strength of the action potentials on the mobile device.

A neuromuscular test device for assessing a level of neuromuscular blocking agents (NMBAs) in an anesthetized patient includes a stimulation circuit for initiating a muscular stimulus in a muscle structure, and a testing circuit for measuring an activity level responsive to the muscular stimulus. A flexible, closed vessel is responsive to a musculature response for inducing a pressure, and a pressure sensor in communication with the closed vessel generates a pressure signal indicative of the musculature response to the muscular stimulus.

A system for treatment of obstructive sleep apnea (OSA) is described. The system includes an introducer needle having an elongated body. The introducer needle is configured to create an opening in a tongue of a patient for implantation of a lead for treating OSA. One or more electrically conductive areas are located on the elongated body. A medical device is configured to deliver a stimulation signal via the introducer needle through the one or more electrically conductive areas to the tongue of the patient to stimulate one or more motor points of a protrusor muscle within the tongue of the patient.

A device for functional electrical stimulation (FES), neuromuscular electrical stimulation (NMES), and/or electromyography (EMG) readout includes a sleeve sized and shaped to be worn on a human arm and comprising an inner sleeve and an outer sleeve. The inner sleeve has openings formed therein, and has an exposed side positioned to contact skin and an opposite backside facing the outer sleeve. Electrode strips each comprise a linear circuit board on which a row of electrodes is mounted. The electrode strips are detachably and selectively mountable to the inner sleeve in a plurality of different orientations. The electrode strips are mountable on the inner sleeve with the linear circuit boards disposed on the backside of the inner sleeve between the inner sleeve and the outer sleeve and the electrodes passing through the openings of the inner sleeve so as to be positioned to contact skin.

According to an aspect, a system for stimulating muscle comprises a set of stimulators to stimulate a first muscles, a set of sensors providing first measurement comprising a set of electromyograms (EMG) from another set of muscles coupled to the body part, a set of sensors mounted in the vicinity of the set of stimulator and the set of sensors, providing a measurement representing a motion and orientation of the first body part, another set of sensors providing a measurement representing a condition external to the body part, a processor generating a first position of the body part at a first time instance from the measurements and a processor adjusting at least one of a time duration, trigger instance, and trigger strength of the set of stimulator. In that, the comparator generates a position error as difference between the first position and a reference.

The provided systems, methods and devices describe lightweight, wireless tissue monitoring devices that are capable of establishing conformal contact due to the flexibility or bendability of the device. The described systems and devices are useful, for example, for skin-mounted intraoperative monitoring of nerve-muscle activity. The present systems and methods are versatile and may be used for a variety of tissues (e.g. skin, organs, muscles, nerves, etc.) to measure a variety of different parameterps (e.g. electric signals, electric potentials, electromyography, movement, vibration, acoustic signals, response to various stimuli, etc.).

In some aspects, the disclosure relates to a prepulse inhibition (PPI) assay comprising the steps of, administering a tactile prepulse to a human subject, administering a startle stimulus to the subject, and measuring the subject's response to the startle stimulus. In another aspect, the disclosure relates to a method for evaluating tactile hypersensitivity and/or sensorimotor impairment in a human subject, comprising, administering to the subject a PPI assay according to any one of the preceding claims, comparing the assay results to neuro-typical controls, and determining the degree of tactile hypersensitivity and/or sensorimotor impairment in the subject.

In some aspects, the disclosure relates to a prepulse inhibition (PPI) assay comprising the steps of, administering a tactile prepulse to a human subject, administering a startle stimulus to the subject, and measuring the subject's response to the startle stimulus. In another aspect, the disclosure relates to a method for evaluating tactile hypersensitivity and/or sensorimotor impairment in a human subject, comprising, administering to the subject a PPI assay according to any one of the preceding claims, comparing the assay results to neuro-typical controls, and determining the degree of tactile hypersensitivity and/or sensorimotor impairment in the subject.