The invention relates to a method and an apparatus for cervical image analysis, wherein a transformation zone is identified in an acetic acid image by registering with its Lugol's iodine counterpart. Then, regions in the transformation zone which show significant changes in whiteness are identified as aceto-white regions and registered with the corresponding Lugol's iodine image, and it is determined if the identified regions in the Lugol's iodine image are iodine negative or positive. Based thereon, the aceto-white region can be categorized as one of metaplasia, inflammation or premalignant lesion region.

Methods and system are described for multi-modal, multi-parametric, non-invasive, and real-time assessment of cervical tissue through a multi-modal probe device for use within a vaginal canal and an associated imaging system to assess a risk of preterm delivery of an expectant mother. The multi-modal system may include ultrasound (US) imaging, viscoelastic (VE) imaging, and/or photoacoustic (PA) imaging of the cervical issue to determine cervical biomarker information indicative of parameters including, but not limited to, a collagen to water ratio such that a more water dominant ratio is indicative of a risk of preterm delivery.

An apparatus includes a shaft having a proximal end and a distal end; a stem extending from the distal end of the shaft and comprising a first cover and a second cover, the, first cover and the second cover being configured to inhibit access to fallopian tubes of a patient; and a plurality of temperature sensors disposed on the shaft and on the stem. At least one of the temperature sensors is positioned between the proximal end of the shaft and the distal end of the shaft and at least one of the temperature sensors is positioned on the stem.

A non-invasive and accurate vagina evaluation device and uterine evaluation devices are provided that measure the receptivity (uterine implantation capacity) of the mother's body to a fertilized egg implanting itself into the uterus. A first vagina evaluation device includes: a main body stretchable and expandable after insertion into a vagina, followed by air injection thereinto; four electrodes brought into contact with the vagina wall as the main body expands and stretches; and fixation means configured to fix the interval of arrangement of the electrodes. Second and third uterine evaluation device include: a flexible and rod-shaped main body for insertion into a uterine cavity; and four or two impedance electrodes arranged with a predetermined interval therebetween in an insertion direction of the main body and brought into contact with an endometrium of the uterine cavity to measure a uterine endometrial impedance generated between the endometrium and each of the electrodes.

An in vivo and insitu diagnostic and light therapeutic tool for the Pap test having a cavity fitting housing with an optical and digital magnification path coupled to image detecting sensor logic. The tool has an optical scraper stem mechanically controlled and extendable from within the housing, the stem having at least one fiber optical channel for selected frequency and wavelength light various light sources, an optical scraper slide component optically coupled to the scraper fiber optic channel stem distal end, channeling light from the housing to the scraper slide normal axis surface for illumination penetrating a specimen sample for optical imaging into an optical microscopy magnification path axis whereby micrograph image from in vivo Pap tests can be accomplished and resulting image micrographs programmatically identified and verified in situ in real-time.

The present invention relates to intravaginal devices, systems including the devices, and methods of using the devices to train an individual in the performance of exercises (e.g., pelvic floor lifts (PFLs) and pelvic floor relaxations (PFRs)) that strengthen the individual's pelvic floor muscles in order to treat or prevent pelvic floor disorders (e.g., pelvic organ prolapse and incontinence) and their accompanying symptoms.

An aspiration device (110) for measuring the viscoelastic deformability of biological tissues and synthetic materials comprises a probe head (11), a probe channel (41), a pressure unit (20), a pressure sensor (31) and a control unit (60). The first probe channel (41) is connecting the pressure unit (20) providing a vacuum with the probe head and includes the pressure sensor (31) detecting the pressure in the first probe channel (41). The first probe channel (41) has a distal end (141) leading with its lower open end (144) through the top wall (14) into the cavity (15) of the probe head. The cavity (15) comprises either an opening (16) in the side or top wall (13, 14) or a second probe channel connected with a valve. A measurement cycle comprises applying under pressure in the first probe channel (41), measuring the under pressure with the pressure sensor (31), detecting a change of under pressure increase over time (301, 401), increasing the under pressure to a predetermined maximum under pressure (303), decreasing the under pressure beyond this point in time and detecting a change of under pressure decrease over time (302, 402).

The present invention relates to a uterine cervical image acquisition apparatus which acquires and displays images of a uterine cervix, and in some cases can automatically diagnose the onset of a disease related to the uterine cervix, the apparatus being characterized by comprising: a main body in which a camera for acquiring uterine cervical images is installed on one side, a user interface for displaying the uterine cervical images and inputting user touch commands is installed on the opposite side, and a handlebar unit is formed in a downward direction; a light source unit which emits light toward the front of the main body; a battery which is positioned inside the handlebar unit to supply power for charging and operation; an operation button unit which includes at least an image capturing button, a zoom-in button, and a zoom-out button formed on the handlebar unit; a memory for storing the captured uterine cervical images; a communication unit for transmitting the uterine cervical images to a reading computer; an image transmission control unit for controlling to store the captured uterine cervical images in the memory, encrypt selected uterine cervical images, and transmit the encrypted images to the reading computer; a display screen control unit which controls to display, on the left and right or above and below the captured uterine cervical display images, a menu bar for receiving the user touch commands; and a camera control unit which controls zooming and auto-focusing of the camera and the brightness of the light source unit according to operations of the provided button.

A system, device, and accompanying software for the remote, three-dimensional, and high-throughput imaging and analysis of human lesions, across a range of wavelengths, lens radii and imaging sensors. This system, device, and software generates and analyses of tumor images at infrared wavelengths through the use of miniaturized, liquid lenses. It has a number of clinical, diagnostic, research, and other imaging applications, including the remote, three-dimensional, and high-throughput imaging and analysis of human cancer tumors.

The invention provides a system (100) for acquiring cervical images which comprises an image acquisition subsystem (120) for acquiring cervical images (122) of a cervical region of a patient during a colposcopy procedure, and a display subsystem (160) for displaying the cervical images on a display (060) by providing image data (162) of the cervical images to the display. According to the invention, the image acquisition subsystem (120) is arranged for, when operating in an interval mode, acquiring the cervical images (122) at predetermined time intervals to obtain a time-series of cervical images showing changes in the cervical region over time, and reporting a progress of said acquiring to the display subsystem. Moreover, the display subsystem (160) is arranged for establishing a progress indicator (400-416) on the display by generating indicator data (164) and providing the indicator data to the display (060), the progress indicator providing visual feedback on the progress of said acquiring to a user. Accordingly, the user is provided with visual feedback on a status of the acquiring of the cervical images. In particular, the progress indicator avoids that the user experiences a loss of control or confusion.