Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

This document relates to computer-based systems and techniques for analyzing skin coloration using spectral imaging techniques to determine a medical condition of an individual. This document further relates to providing feedback to a rescuer or other medical professional based on the colorimetric properties of the patient's skin.

The present disclosure is generally directed to a swab and an apparatus for testing dental cold sensitivity. The swab comprises a hollow tube and an absorbent tip fixedly attached to the distal end of the hollow tube. The dispensing apparatus includes a pressurized container and an actuator. The actuator may include a flow control valve to limit the flow of coolant to the absorbent tip or to limit the volume to a metered dose and to prevent the swab from being ejected from the actuator due to excess force.

A cognitive function determination method includes applying a load including a sensory stimulus (5a) or tasks with different degrees of difficulty a plurality of times (S1), measuring a change in brain activity of a subject (P) when the load is applied and acquiring measurement data (S2), and determining a degree of cognitive function of the subject (P) (S3).

Provided herein are methods to predict pain sensitivity and pain intensity to prolonged pain in a subject. Electroencephalograms are recorded in a pain-free state or, alternatively, in a pain-free state and after applying a prolonged pain stimulus in a prolonged pain state. Pain-free and prolonged pain peak alpha frequencies or PAF are measured. These values correlate negatively with the likelihood of increased pain sensitivity and increased pain intensity. Also provided is a method for predicting a likelihood of chronic pain in a subject after a medical procedure and designing a plan to treat the chronic pain.

An injectable electrode which is manufactured in the body by curing from a liquid phase to a solid phase, and therefore molding to the contours of the bodily structures where it is injected.

The objective of the present invention is to provide a technique which enables analysis to be performed in real-time without taking a control or the like, by performing wavelet transformation at the same time, without pre-processing of a signal. The present invention provides a pain estimating method and device with which pain of an estimation target can be objectively and accurately estimated, and with which the quality and quantity thereof can be classified simply. The present invention provides a method for processing a signal of a target in response to a stimulus, and includes: a) a step of obtaining from the target a signal in response to a stimulus; (b) a step of subjecting the signal to cross correlation processing using part or all of the signal; and (c) a step of calculating a feature quantity of the signal and a coefficient correlated to the stimulus from the processing results obtained in b).

The inventive concept refers to a system, a method, and a computer program for providing training for pain improvement. According to an exemplary embodiment, a training providing method for pain improvement includes requesting, by a computer, a temperature providing device to provide a first temperature to a first body point, requesting, by the computer, the temperature providing device to provide a second temperature to a second body point, requesting a user to select a temperature matched with a specific condition among the first temperature and the second temperature, and calculating a correct answer rate after performing a trial of distinguishing between the first temperature and the second temperature by a predetermined number.

A training and simulation assembly for the learning of deliberate control of a specified body part by a test subject contains an electrode cap, which has a number of electrodes, and an evaluation unit, which is configured to measure voltages present at the electrodes and to provide measurement results as EEG measurement data. The evaluation unit analyzes the EEG measurement data for the presence of a mental act and to determine a correspondence value, which indicates the correspondence of the EEG measurement data with reference values defined by the mental act. A control unit and a simulation unit are provided. The simulation unit stimulates the body of the test subject at a specified point of the body and/or to trigger a motion. The control unit controls the stimulation unit and the ability to apply an indicating stimulus to the body part by the stimulation unit.

A minimally invasive, microchip-based system which enables continuous long-term recording of subjects (e.g., freely moving rodents) under study including subject behavior, subject brain neurovascular activity, subject heart rate, subject intercranial pressure, subject temperature, and subject head movement is described herein. These systems may also include microchips configured to deliver stimuli such as heat stimuli and measure these various parameters of subjects before, during, and after stimuli. The systems may afford measurement protocols in one or more subjects such as conditioned place/aversion assays and/or pharmacological or medical device testing.