Systems, methods, apparatus, and non-transitory computer readable media for measuring and analyzing galvanic skin response. A system for measuring galvanic skin response includes an electrical conductivity meter (ECM) electrically connected to a positive electrode and a negative electrode and a server platform in network communication with the ECM. The ECM includes at least one processor and at least one memory. The positive electrode is in contact with a point on a hand or a foot of a subject. A circuit is created between the ECM and the subject including the positive electrode and the negative electrode. The positive electrode includes a pressure sensor to indicate an amount of pressure applied by a tip of the positive electrode on the point. The server platform includes artificial intelligence (AI) algorithms to detect variations in the pressure applied by the positive electrode during a session and/or across multiple sessions.

The disclosure describes devices and methods for providing transdermal electrical stimulation therapy to a subject including positioning a stimulator electrode over a glabrous skin surface overlying a palm of the subject and delivering electrical stimulation via a pulse generator transdermally through the glabrous skin surface and to a target nerve or tissue within the hand to stimulate the target nerve or tissue within the hand so that pain felt by the subject is mitigated. The pulses generated during the electrical stimulation therapy may include pulses of two different magnitudes.

A device includes a main body having a length, a first end, a second end, and an axis along the length. A first electrode is associated with the first end of the main body. A suspension structure is associated with the second end of the main body. The suspension structure is configured for displacement in a direction of the axis of the main body, and includes a flexible isolation ring defining an opening, and a second electrode that is associated with the opening and mechanically coupled to the flexible isolation ring. The device also includes an electronics assembly with a first subassembly that is electrically coupled to the first electrode and secured relative to the main body to prevent displacement of the first subassembly in a direction of the axis of the main body, a second subassembly that is arranged to electrically couple with the second electrode. A flexible coupling between the first subassembly and the second subassembly enables displacement of the second subassembly relative to the first subassembly and in a direction of the axis of the main body.

Various embodiments include methods and devices for measuring blood pressure. Various embodiments may include receiving, from one or more arterial measurement sensors, a pulse waveform representing arterial pressure as a function of time for each pulse of a series of blood pressure pulses. The series of blood pressure pulses may be correlated to arterial distension at a measurement location of the arterial measurement sensors on a subject's body. One or more elevations of the measurement location may be received from one or more elevation sensors. At least one pulse in the series of pulses may be identified that represents a transitional pulse based on one or more characteristics of the at least one pulse. A diastolic blood pressure may be determined based on the at least one identified transitional pulse and elevation measurements that correspond to the one identified pulse.

A testing device for providing realistic response and sensor-driven data for determining the effects of physical loads on the testing devise and the effectiveness of personal protective equipment is disclosed. The testing device includes a body simulating a portion of the human body, and one or more sensors. In some embodiments, the body includes two or more body portions joined to one another. In some embodiments, the body portions may articulate with respect to one another. In some embodiments, the testing device includes an internal frame.

A non-invasive glucose sensor used for glucose detection in a subject is provided. The sensor includes a long channel source to excite a first location of a skin and a long channel detector to detect near infrared (NIR) energy emitted from the first location of the skin. A short channel source excites a second location of the skin and a short channel detector detects NIR energy emitted from the second location of the skin. The sensor further includes a long channel processor to process a long channel electrical signal into a glucose spectroscopic data and a short channel processor to process a short channel electrical signal into a background spectroscopic data. The sensor includes a spectroscopic processor to subtract the background spectroscopic data from the glucose spectroscopic data, and thereby to produce data indicative of a quantity of glucose present in the subject's blood.

Systems and methods for tracking unintentional muscle movements of a user and stabilizing a handheld tool while it is being used by the user are described. The method may include detecting motion of a handle of the handheld tool manipulated by a user while the user is performing a task with a user-assistive device attached to an attachment arm of the handheld tool. Furthermore, the method may include storing the detected motion in a memory of the handheld tool as motion data. The method may also include controlling, based on the motion data, a motion-generating mechanism of the handheld tool that moves the attachment arm relative to the handle in a single degree of freedom in a direction of the detected motion of the handle.

A flexible circuit package. The circuit package includes a termination point on a flexible base substrate. The termination point is connected with an interface by conductive material on the base substrate. The conductive material extends across the surface area of the base substrate in multiple individual connections, which are in communication with each other and separated by voids in the conductive material for mitigating communication failure between the termination point and the interface during or following flexion, stretching, compression or other deformation of the base substrate and the circuit package. The termination point may include an input module such as a sensor, switch or other input. The termination point may include an output module such as a light, vibrator or other output. The interface may include an output interface for receiving data or an input interface for sending a command or other signal.

Light-based non-invasive blood pressure measurement systems and methods that include a sensor having a light emitter and a light detector are disclosed. The light emitter emitting coherent or non-coherent light that is transmitted into and reflected from the tissues of the patient, including reflecting from moving blood. The light reflected from the moving blood being having a Doppler shift and detected by the light detector to generate a noninvasive blood pressure signal. The non-invasive blood pressure signal is processed to determine the instantaneous velocity of the blood. Additionally, pulse wave velocity data is obtained nearly, or substantially, simultaneously with the acquisition of the non-invasive blood pressure signal. Using the pulse wave velocity, the instantaneous velocity of the blood and a density of the blood, an instantaneous blood pressure can be determined.

The present invention is directed to a system for monitoring a physiological parameter of a cyclist, and methods of using the system. The system comprises a garment, a sensor, and a signal processor. The garment is configured to be worn by the cyclist. The sensor is fixedly coupled to the garment and configured to measure a signal representative of the physiological parameter during pedaling. The signal processor is operatively coupled to the sensor and configured to determine a diagnosis based on the measured signal. An alert is generated in response to the diagnosis substantially in real time.