This invention relates to a vacuum-pump sucker for high-resolution microscopy comprising a sucker body and a transparent plate. The vacuum-pump sucker is designed as a stabilizer for sample stabilization in a clinical optical virtual biopsy system with sub-micron resolution. The sucker is connected with a vacuum pump. As the vacuum pump pumps out air or gas, tissues around the imaged area will be sucked by the sucker and the distance between objective lens and the imaged tissue can be stabilized. In this way, the stability and resolution of the clinical biopsy system can be greatly improved.

A sweat sampling and sensing device for sensing sweat on skin includes an analyte-specific sensor for sensing a first analyte in sweat; a sweat collector placed on or adjacent to skin with a plurality of pores or pathways for entry of sweat from skin into said sweat collector, said sweat collector at least partly defining a sweat volume between said analyte-specific sensor and the skin; and a pressure element capable of holding said sweat collector against the skin with a pressure and reducing the sweat volume between said sweat collector and the skin.

A pulse oximetry device is provided that fixates generally around a user's wrist. The device may include one or more mechanical features that fix the device at, for example, a distal end of a wearer's ulna bone. The device may include one or more projections formed from a suitable material (e.g., elastomer such as silicon) that cause the device to fit snugly against the wearer's wrist and remain in place even when the wearer is moving, thus reducing motion artifacts in signals detected by the device. The device may include one or more mechanical features or fins that reduce ambient or stray light in the measurement area. The device may include one or more detectors, and one or more light sources, each having a different axis resulting from the manner in which each is angled toward a virtual center point of the distal end of a wearer's ulna bone.

The present disclosure discloses a guarding wall mechanism (100) for an optical fiber (101). The mechanism (100) comprises a housing (202) adapted to house the optical fiber (101), wherein the housing (202) defines a space (108) between the optical fiber (101) and a guarding wall of the housing (202). A plurality of suction units (103) disposed in the space (108). Each of the plurality of suction units (103) are configured to selectively exert suction pressure on an examination surface in contact with a free end (109) of the optical fiber (101). The guarding wall mechanism (100) of the present disclosure eliminates leakage of light and reduces Fresnel losses. Also, the mechanism (100) improves comfort to the patient during examination.

A novel medical imaging system that is based on radio-wave signals at microwave frequencies and has unique properties. The system can be used for various diagnostic applications such as breast cancer detection, brain stroke detection, and assessment of internal bleeding (trauma emergencies).

A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

Wearable sensor patches, applicator systems for applying wearable sensor patches, and associated systems, devices, and methods are disclosed herein. In one embodiment, an applicator system includes a first applicator portion, a second applicator portion, a spring, and a trigger mechanism. The first applicator portion releasably retains a wearable sensor patch configured to detect a parameter of an analyte in fluid of a user. When the applicator system is in a loaded mode, the spring and the first applicator portion are positioned within the second applicator portion such that the spring is positioned between the first applicator portion and the second applicator portion. The trigger mechanism is configured to initiate a transition of the applicator system from the loaded mode to a released mode such that the spring accelerates the first applicator portion distally away from the second applicator portion to apply the wearable sensor patch to the user.

The present invention relates to a sampling unit, a measurement system and method for transcutaneous blood gas measurements. In particular the invention relates to a sampling unit and system adapted for rapid measuring and monitoring of blood gases in a continuous gas flow. The sampling unit is provided with an ambient air inlet and a blood gas extraction and mixing chamber wherein air is mixed with extracted blood gases. The method of continuous transcutaneous measurement of carbon dioxide in the blood utilizes a pulsed heating to minimize the detrimental effects of the heating.

An apparatus (10) serves for attachment of a light receiving device (24) for light analysis on an instrument (11) or an instrument component (12) during surgery by the surgery user of a surgical instrument (11) or their assistant. The apparatus (10) is preferably configured to releasably attach the light receiving device (24) on the instrument (11) or the instrument component (12). The apparatus (10) can comprise a light receiving device (24) and an electrode (15) fixed relative thereto. The electrode (15) can alternatively also be part of the instrument (11). The apparatus (10) can be releasably attachable to the instrument (11) or the instrument component (12) and can form an adapter for attachment of the light receiving device (24) on the instrument (11) or the instrument component (12) or can also be configured as part of the instrument (10).

A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.