An example system is disclosed for generating a model of a tubular anatomical structure. The system includes an anatomical measurement wire (“AMW”), a tracking system and a computing device. The AMW is configured to be navigated through the anatomical structure of a patient, and the AMW includes at least one sensor. The tracking system is configured to provide tracking data representing multiple positions of the sensor in a spatial coordinate system. The computing device is configured to generate a data point cloud based on the tracking data, generate a parametric model corresponding to at least a portion of the vessel based on the data point cloud and store the parametric model in non-transitory memory.

In part, the disclosure relates to computer-based methods, devices, and systems suitable for performing intravascular data analysis and measurement of various types of data such as pressure and flow data. The disclosure relates to probes and methods suitable for determining an event in a cardiac cycle such as flow threshold such as a peak flow, a fraction thereof, other intravascular parameters or a point in time during which peak flow or a change in one of the perimeters occurs. An exemplary probe includes one or more of a pressure sensor, a resistor, a flow sensor and can be used to generate diagnostic data based upon measured intravascular and other parameters. In part, the disclosure relates to methods and systems suitable for determining a coronary flow reserve value in response to one or more of intravascular pressure and flow data or data otherwise correlated therewith.

This disclosure relates generally to systems and methods for characterizing a behavior of an anatomical structure. Tracking data can be generated by a tracking system to represent at least a location of at least one sensor in a three-dimensional tracking coordinate system over time. A motion model is generated to characterize the behavior of the anatomical structure over a plurality of time instances. For instance, the motion model includes at least one free parameter and a temporal parameter. Each free parameter estimating geometry of the anatomical structure derived from the tracking data, and the temporal parameter indexes the free parameter over the plurality of time instances. A visualization is generated to provide a sequence of graphical images based on the motion model to characterize behavior of the anatomical structure over time.

An optical connector including a first optical fiber having a first diameter and having a core that includes a thermally expanded core portion adjacent a first end of the first optical fiber, a second optical fiber spliced to a second end of the first optical fiber, the second optical fiber having a second diameter less than the first diameter, and a connector bore having a first bore portion configured to receive the first end of the first optical fiber.

A tracking system for tracking a marker device for being attached to a medical device is provided, whereby the marker device includes a sensing unit comprising a magnetic object which may be excited by an external magnetic or electromagnetic excitation field into a mechanical oscillation of the magnetic object, and the tracking system comprises a field generator for generating a predetermined magnetic or electromagnetic excitation field for inducing mechanical oscillations of the magnetic object, a transducer for transducing a magnetic or electromagnetic field generated by the induced mechanical oscillations of the magnetic object into one or more electrical response signals, and a position determination unit for determining the position of the marker device on the basis of the one or more electrical response signals.

Devices for localizing an intracerebral hematoma or blood mass in brain tissue. The devices include an elongate probe a color sensors and a light emitter on the distal end of the probe. The color sensors produce a signal corresponding to the color of light reflected into the color sensors. A display is provided to indicate the color detected.

A guidewire system comprises a guidewire supporting a distal ferrule in the proximal end of a guidewire lumen. The distal ferrule has a ferrule opening that is sized to snuggly receive the proximal end of a distal optical fiber with a distal portion of the distal optical fiber extending into the guidewire lumen. However, the proximal end of the distal optical fiber only occupies a distal portion of the opening in the distal ferrule, leaving a proximal portion of that opening unoccupied. That way, the distal end of a proximal optical fiber can be received into the unoccupied proximal portion of the opening in the distal ferrule to optically connect to the distal optical fiber. Having the proximal and distal optical fibers coaxially aligned in a common opening in a ferrule received in a guidewire ensures that the optical fibers are optically connected to each other in a precise manner so that light can be transmitted along them with minimal losses.

A sacral lead system including a sacral lead configured to for insertion within a sacral foramen of a patient. The sacral lead supports one or more electrodes which may be configured as one or more stimulation electrodes and/or one or more sensing electrodes. The sacral lead is configured to deliver a stimulation signal to a patient using at least one stimulation electrode and sense an evoked signal produced in response to the stimulation signal using at least one sensing electrode. The sacral lead system may be configured to position the at least one stimulation electrode and/or the at least one sensing electrode within, dorsal, or ventral to the sacral foramen. The sacral lead system may include stimulation circuitry configured to generate the stimulation signal and sensing circuitry configured to receive a signal indicative of the evoked signal.

A catheter system includes an elongated tube structure configured for insertion into a luminal space, such as the vasculature, of a body. The catheter is conductive and configured to conduct electrical signals. The catheter includes one or more power and data coupling devices configured to send and receive power and/or data signals, such as from an underlying guidewire disposed within a lumen of the catheter. One or more sensors are coupled to a distal section of the catheter and are electrically connected to the one or more power and data coupling devices.

The application describes embodiments including, e.g., a measurement device comprising: a casing, a first magnet arranged within the casing such that it is rotatable out of an equilibrium orientation responsive to an external magnetic torque acting on the first magnet, a second magnet to provide a restoring torque to force the first magnet back into the equilibrium orientation responsive to an external magnetic torque rotating the first magnet out of the equilibrium orientation, allowing for a rotational oscillation of the first magnet, which is excited by the external magnetic torque, with a resonant frequency, and a temperature sensitive magnetic material to modify the resonant frequency.