Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat.

In one embodiment, a device for in vivo tissue evaluation includes an elongated manipulator including an elongated proximal tube and an articulable distal portion, and a sensor provided at a distal end of the articulable distal portion, the sensor including a sensor head configured to be pressed against tissue and measure a reaction force of the tissue.

A method for performing an efficient and thorough percutaneous discectomy includes making into the patient a percutaneous incision, which is a small stab wound, no more than approximately 10 mm in length. A stimulated combination neuro-monitoring dilating probe is passed through an approximately 10 mm or less skin incision and into a patient's disc space to establish a safe path and trajectory through Kambin's Triangle. Once a neuro-monitoring dilating probe is in the disc space, a second dilator is placed over the neuro-monitoring dilating probe and impacted into the disc space. Neuro-monitoring dilating probe may then be removed. An access portal optionally combined with a force dissipation device may then be placed over the second dilator and into the disc space. The second dilator is removed and then discectomy instruments may be placed through the access portal to perform the discectomy.

A hemodynamic monitoring system monitors arterial blood pressure of a patient and provides a warning to medical personnel of a predicted future hypotension event of the patient. Sensed hemodynamic data representative of an arterial pressure waveform of the patient are received by a hemodynamic monitor. The received hemodynamic data is offset, based on a difference between a standard mean arterial pressure (MAP) threshold for hypotension and an adjusted MAP threshold for hypotension, to produce adjusted hemodynamic data. Waveform analysis of the adjusted hemodynamic data is performed, and a risk score representing a probability of a future hypotension event for the patient is determined based on the waveform analysis. A sensory alarm is invoked to produce a sensory signal in response to the risk score satisfying a predetermined risk criterion.

In one embodiment, a medical system includes a catheter to be inserted into a chamber of a heart, and including electrodes to capture electrical activity of tissue of the chamber over time, a display, and processing circuitry configured to compute a propagation of a cardiac activation wave over an anatomical map of the chamber from a start time in a cardiac cycle to an end time in the cardiac cycle responsively to the captured electrical activity, render to the display a sub-region of the anatomical map, select a time-bounded portion of the propagation of the cardiac activation wave commencing at a time after the start time responsively to when the propagation would commence to be rendered in the sub-region of the anatomical map, and render to the display the time-bound portion of the propagation of the cardiac activation wave on the sub-region of the anatomical map.

An illumination system for a medical technology therapy and/or diagnosis system is provided. The system includes a light source, an optical waveguide, and an optical element in the form of a diffuser element. The optical waveguide has a first end that is connectable or assignable to the light source and the diffuser element is arranged at a second end of the optical waveguide so that light from the optical waveguide is injected into the optical element. The optical element has a lateral surface covered by a reflector layer at least in a section thereof. The reflector layer includes a mirror layer. The optical element has a light-reflecting area covered by the reflector layer and a light-transmissive area that is free of the reflector layer. Thus, light injected into the optical element is reflected on the light-reflecting area and emitted from the light-transmissive area.

An ultrasound transducer assembly that includes a piezoelectric layer configured to resonate and generate ultrasound signals around a predetermined ultrasound frequency in which the piezoelectric layer has a width to thickness ratio of at least about 0.6. A conductive matching layer is connected to the top surface of the piezoelectric layer to condition the ultrasound transducer for broad frequency bandwidth operation. A conductive backing layer is connected to the bottom surface of the piezoelectric layer. The ultrasound transducer assembly further includes a rigid body over which the conductive backing layer is positioned, the rigid body assembled for encompassing a central longitudinal axis of a catheter body. A signal and ground electrode may form a metallic layer over the top of or below each of the piezoelectric layers. Electrical waveguides may be connected to corresponding signal and ground electrodes of the transducers.

The present disclosure relates to systems and methods to magnetically influence the position, orientation, movement, and/or activation of a medical device within an operating region within the body using a magnetic guidance system introduced into a target location of a body. More specifically, the present disclosure relates to magnetic navigation systems for applying a magnetic field to an operating region within the body, the system comprising a first magnet assembly configured for introduction into a target location of a body and a second magnet assembly disposed opposite the first magnet assembly, wherein the first and second magnet assemblies are configured for applying a magnetic field to an operating region between the magnet assemblies.

The present invention provides scanning mechanisms for imaging probes using for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism having including a movable member configured to deliver the energy beam along a path out of said elongate hollow shaft at a variable angle with respect to said longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.

An apparatus includes a current source, an electronic circuit and a circuit board. The current source is configured to flow an electrical current having a selected frequency between a pair of electrodes coupled to a medical probe. The electronic circuit is configured to measure a single-ended voltage relative to ground that is formed on at least one of the electrodes in the pair in response to the electrical current, and, based on the measured voltage, to assess physical contact between the at least one of the electrodes and tissue. The circuit board includes the current source and the electronic circuit, and includes a layout that produces, at the selected frequency, a predefined capacitance between the current source and ground, thus forming a reference for measurement of the single-ended voltage.