Graphical User Interface (GUI) control of a stimulator device is disclosed. The GUI receives modeling information indicating optimal stimulation parameters for a patient based on patient testing, and may also receive an indication of a particular stimulation mode to be used for the patient which comprises a subset of those parameters. The GUI provides simple options to allow a user to navigate the optimal parameters or subsets to constrain selection to only those stimulation parameters set within the optimal parameters or subsets.

A tissue monitoring system includes a sensor, a sensor reader, and at least one computing device. The sensor is releasably coupled to a staple by a tether and is configured to measure a physiological parameter of tissue and convert the measurement into a signal. The sensor reader is configured to receive the signal from the sensor and the at least one computing device is configured to receive the signal from the sensor reader and process the signal into physiological data. The sensor is implanted in tissue by the staple.

Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.

The present disclosure relates generally to bioactive releasing membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the disclosure relates to novel bioactive releasing membranes, to devices and implantable devices including these membranes, methods for forming the bioactive releasing membranes on or around the implantable devices, and to methods for monitoring analyte levels in a biological fluid sample using an implantable analyte detection device.

Systems and methods are described herein for selection of a cardiac cycle, or heartbeat, from a plurality of cardiac cycles monitored over time. The cardiac cycle may be selected using various metrics including a single-cycle metric and a cycle-series metric. Further, the selected cardiac cycle may be used for further cardiac analysis (for example, to generate electrical activation times).

Described herein are methods, devices, and systems that identify ventricular sensed (VS) events from a signal indicative of cardiac electrical activity, such a far-field EGM or ECG signal, and monitor for an arrythmia and/or perform arrythmia discrimination based on the VS events. Beneficially, such embodiments reduce the probability of double-counting of R-wave, or more generally, of oversensing VS events, and thereby provide for improved arrythmia detection and arrythmia discrimination.

Medical devices are provided, comprising a medical device and a sensor.

A system for installing a sensor, comprising: a puncture device comprising: a casing defining a cavity; an elongated member a sharp end; and a sensor assembly for measuring data about the body, the sensor assembly comprising: a sensing unit comprising a sensor for measuring the data and being engageable with the elongated member; a data unit for collecting the data, the data collecting unit being receivable within the cavity of the casing; and a communication cable extending between the sensing unit and the data collecting unit for transmitting the data to the data unit; wherein the sensor assembly is removably securable to the puncture device by inserting the data unit in the cavity of the casing and engaging together the sensing unit and the elongated member, the communication cable being tensed when the sensor assembly is secured to the puncture device.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and/or left ventricular pressure.

Sense amplifier circuits particularly useful in sensing neural responses in an Implantable Pulse Generator (IPG) are disclosed. The IPG includes a plurality of electrodes, with one selected as a sensing electrode and another selected as a reference to differentially sense the neural response in a manner that subtracts a common mode voltage (e.g., stimulation artifact) from the measurement. The circuits include a differential amplifier which receives the selected electrodes at its inputs, and comparator circuitries to assess each differential amplifier input to determine whether it is of a magnitude that is consistent with the differential amplifier's input requirements. Based on these determinations, an enable signal is generated which informs whether the output of the differential amplifier validly provides the neural response at any point in time. Further, clamping circuits are connected to the differential amplifier inputs to clamp these inputs in magnitude to prevent the differential amplifier from damage.