A fully implantable sensor for detecting an analyte in a body fluid sample is disclosed. The sensor includes a chamber plate that receives the body fluid sample. The chamber plate has a biocompatible polymer membrane having a molecular weight cutoff of at least 15 kDa. The sensor also includes a quantum cascade laser illumination source that generates an illumination light beam in a spectral range and transmits the light beam to the chamber plate. In response to the illumination light beam at least partially illuminating the chamber plate, the chamber plate generates a reflection light beam that at least partially illuminates the body fluid sample within the chamber plate. The sensor has an optical detector that detects at least one property of the reflection light beam and generates a sensor signal that correlates to the presence of the analyte. The sensor includes a controller to evaluate the sensor signal.

Systems and methods for remotely monitoring blood flow that include an endovascular prosthesis. The endovascular prosthesis includes a conduit forming a lumen within a surrounding wall having an inner surface and an outer surface. A monitoring device is disposed on the wall forming the lumen. The monitoring device comprises a sensor element configured to detect a physical event and to generate an electrical parameter shift in response to the physical event. An antenna portion is configured to receive a first oscillating electrical signal from an interrogator device and to transmit a second oscillating electrical signal to the interrogator device. The second oscillating electrical signal is modulated by the electrical parameter shift.

A medical device for treating an associated patient includes a bronchial sensor device configured to measure fluid pressure in a bronchus of the associated patient; and an electronic controller configured to: receive the fluid pressure data from the bronchial sensor device; and calculate a fluid flow measurement through the bronchus based on the measured fluid pressure.

The invention relates to a method for discriminating cells of a cellular structure, notably of a cellular tissue, comprising the steps consisting in determining (12) a frequency spectrum of the impedance of the cellular structure; defining (22) at least one model of the impedance of the cellular structure including a constant phase element (30); determining (44) the impedance of the constant phase element (30) which optimizes the correlation of each model of the impedance of the cellular structure with the spectrum; and deducing (66), from the impedance of the constant phase element (30) or from the impedances of the constant phase elements (30), an item of information on the cells of the cellular structure. The invention also relates to a system for implementing the method for discriminating cells of a cellular structure.

Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.

Anchors and anchoring methods suitable for use with implantable assemblies that include an implantable device, including but not limited to implantable sensing devices and implantable wireless sensing devices adapted to monitor physiological parameters within living bodies. Such an implantable device has a housing containing a transducer, electrical circuitry, and an antenna. The transducer is located at a first end of the housing opposite a second end of the housing. At least the transducer is located within a housing portion of the housing in which the antenna is not located. The implantable assembly further includes an anchor is adapted for securing the implantable device within a living body.

An implantable sensor for implantation in a vessel, comprising a plurality of electrodes for placement on, in or adjacent a vessel wall, means for providing a drive signal to the electrodes, means for measuring at least one of impedance and capacitance between at least two of the plurality of electrodes, and means for wirelessly communicating data from the sensor and a blood vessel monitoring system comprising same.

A sensor implant device includes a shunt body that forms a fluid conduit, a first anchor structure associated with a first axial end of the shunt body, and a first sensor-retention structure associated with a second axial end of the shunt body, the first sensor-retention structure being configured to hold a first sensor device in a sensing position in which a sensor transducer of the first sensor device is disposed at least partially radially outside of a channel area of the fluid conduit.

In some embodiments, systems, methods and devices for using passive pressure sensors to measure pressure at an inaccessible location are provided. In some embodiments, a system for determining pressure in a ventriculoperitoneal shunt implanted in a subject is provided, the system comprising: an acoustic source emitting signals over a range of frequencies; the ventriculoperitoneal shunt, comprising: a lumen that provides a conduit for cerebrospinal fluid between; and a passive acoustic element in a wall of the ventriculoperitoneal shunt filled with a gas, wherein the passive acoustic element emits a second signal at a resonant frequency that varies based on the pressure on the passive acoustic element; an acoustic receiver that detects the second signal and outputs an electrical signal that represents at least the resonant frequency; and a processor programmed to: receive the electrical signal; determine the pressure using the resonant frequency; and present the pressure using a display.

Some implementations of an endovascular device include a stent graft with an expandable tubular metallic frame and a covering material disposed on at least a portion of the metallic frame. The stent graft defines a lumen therethrough. In a particular embodiment, a first balloon is disposed around an outer periphery of the stent graft, a second balloon is disposed around the outer periphery of the stent graft and spaced apart from the first balloon, and a third balloon is disposed within the stent graft lumen between the first balloon and the second balloon. The third balloon can be inflated to fully or partially occlude the lumen. The first and second balloons can be individually inflated to fully or partially shunt blood flow from a blood vessel through the stent graft. In some embodiments, sensors and an automated control unit are included to automate the operations of the endovascular device.