Absolute blood volume in dialysis patients is a useful patient attribute to know for dialysis treatment, diagnosis, adjustments, etc. In some cases, it is difficult or impossible to directly determine absolute blood volume. Estimating absolute blood volume may be used to overcome the inability to directly determine the absolute blood volume. Estimating absolute blood volume may include obtaining a series of measurements of hemoconcentration of a patient over a time period, and estimating parameters for a physiological model based on the series of measurements. The absolute blood volume of the patient may be determined using the physiological model.

Described is a cannula (110 to 1110, CA1500, CA1600) for detection of the volume (V) of a cavity within a body (100), comprising: a lumen portion (LP) comprising and inner surface (ISF) and an outer surface (OSF), a first opening (OP1) on a first end (FE) of the lumen portion (LP), a second opening (OP2) on a second end (SE) of the lumen portion (LP), wherein the first opening (OP1) and the second opening (OP2) have an inner diameter that allows endovascular blood circuit support of the blood circuit of a subject (Pat), a lumen (LU) extending from the first end (FE) to the second end (SE) within the lumen portion (LP), and at least one series (SER1) of electrodes (EE1 to EE2) comprising at least two electrodes (EE1 to EE2), wherein the series of electrodes (EE1 to EE2) is arranged along at least a part of the lumen portion (LP) at the outer surface (OSF), wherein the at least one series (SER1) of electrodes (EE1 to EE2) is configured to be used for the detection of the amount of a volume (V) of a cavity within a body (100) of the subject (Pat).

Detailed herein are systems, methods, and devices configured for detecting symptoms of depression in a home dialysis patient. These systems, methods, and device may be embodied in a home dialysis system. The home dialysis system may be configured to carry out a home dialysis treatment on a patient. During the home dialysis treatment, the home dialysis system may be configured to detect one or more symptoms of depression and to generate a medical alert based on the detected one or more symptoms.

The invention relates to a medical technology measuring system (1) comprising a measuring device (10) for measuring a characteristic of a fluidin particular, for pressure measurementwherein the measuring device comprises a lead (20) which extends along a central longitudinal axis (M) and is equipped to guide a fluidin particular, bloodinside a longitudinal cavity (24) enclosed by a wall, and a sensor device (30) comprising a sensor (32) which is equipped to measure a characteristic of the fluid guided in the longitudinal cavity, wherein the measuring system (1) has an overmolding (9) which at least partially surrounds the measuring device (10)preferably, both at least the sensor device (30) and also a section of the lead (20). As a result, the measuring device can be fastened and positioned on the lead in a simple and/or reliable, robust manner. The invention further relates to a method for producing such a medical technology measuring system.

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

A system and method for automatic detection of symptoms of peritonitis during peritoneal dialysis, such as using a mobile device with an image capturing system.

To provide an exercise support apparatus that can offer safer exercise to be taken during blood purification treatment. An exercise support apparatus is capable of supporting exercise taken by a patient during blood purification treatment and includes an estimation-line-generating device that generates an estimation line representing a course of circulating-blood-volume rate of change (BV) as a parameter regarding changes in circulating blood volume of the patient that is estimated to be observed after the exercise is started, the estimation line being generated after the blood purification treatment is started and from a continuous measurement of the circulating-blood-volume rate of change (BV) as the parameter regarding changes in circulating blood volume that is conducted before the exercise is started; a first calculating device that calculates a difference or ratio between a measured value of the circulating-blood-volume rate of change (BV) of the patient that is acquired after the exercise during the blood purification treatment is started and a value of the estimation line generated by the estimation-line-generating device; and a first monitoring device that monitors whether or not the difference or ratio calculated by the first calculating device is over a predetermined threshold.

A peritoneal dialysis (PD) fluid line set includes a fluid line configured to carry spent dialysate to a drain receptacle and a chemical testing device disposed along the fluid line. The chemical testing device is configured to detect a presence of a substance in the spent dialysate as the spent dialysate flows past the chemical testing device, and the chemical testing device is configured to provide a visual indicator of the presence of the substance in the spent dialysate.