The capsule includes a tubular body and a front-end unit including an anchoring member for the anchoring of the capsule to a wall of a patient's organ. The front-end unit is mobile in relative axial rotation with respect to the tubular body, and a disengageable coupling member is adapted to allow this relative rotation when the tubular body receives an external rotational stress, the anchoring member then exerting a reaction torque higher than a predetermined threshold torque, and to prevent the relative rotation in the absence of external rotational stress applied to the tubular body. The coupling member may in particular include, between the front-end unit and the tubular body, a friction interface, with an elastically deformable element applying an axial compression between a bearing face of the tubular body and a support ring integral with the anchoring member.

The invention relates to a device (105) for determining a cardiac output for a cardiac assist system (100), wherein the device (105) comprises a support structure (115) and a sensor device (120). The support structure (115) comprises at least one brace (125) and a connection section (130) for connecting the device (105) to an element (110, 112) of the cardiac assist system (100). The at least one brace (125) is connected to the connection section (130) and can be folded away from the element (110, 112). The sensor device (120) is coupled to the at least one brace (125) and configured to sense a blood stream.

Certain aspects of the present disclosure provide methods and apparatus for determining a precise localization of an arrhythmia origin or exit site in a heart of a subject using internal electrocardiograph (ECG) signals sensed and stored by an implantable device implanted in the subject. One example method of analyzing an arrhythmia in a subject generally includes reading, from an implantable device implanted in the subject, a plurality of internal ECG signals sensed and stored by the implantable device while the subject was experiencing an arrhythmia event (e.g., at any time, including while the subject was ambulatory); performing an analysis of the read internal ECG signals; and determining a localization of the arrhythmia associated with the arrhythmia event, based on the analysis.

A system and method for training a neural network to automatically detect a cardiac structure of interest including a processor comprising a neural network training model that receives training data. The training data comprises a first input comprising first electrophysiological data regarding a first cardiac structure received by an electrode of a first catheter positioned within a heart, and a second input comprising a second data relating to the first cardiac structure. The neural network training model generates, as an output, a determination of whether the first cardiac structure is the cardiac structure of interest based on the training data.

The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes interatrial shunting systems that include a shunting element having a lumen extending therethrough that is configured to fluidly couple the left atrium and the right atrium when the shunting element is implanted in a patient. The system can also include an energy receiving component for receiving energy from an energy source positioned external to the body, an energy storage component for storing the received energy, and/or a flow control mechanism for adjusting a geometry of the lumen.

Modulation of foreign body responses in living tissue, and more particularly, devices and related methods for light-based modulation of foreign body responses in living tissue are disclosed. Light sources are disclosed that provide light with characteristics for modulation of foreign body responses that may be elicited by percutaneous and/or subcutaneous devices, including medical devices and other consumer electronic devices. Light delivery structures are disclosed that propagate light from the light sources to irradiate associated subcutaneous tissues. Modulation of foreign body responses may include inhibiting collagen and fibrous tissue generation, modulating inflammation and healing, and/or increasing nitric oxide production and/or release. By modulating foreign body responses associated with percutaneous and/or subcutaneous devices, performance characteristics and lifetimes of such devices may be improved.

Various aspects of the present disclosure are directed toward apparatuses, systems and methods that include arranging an acute alteration of blood flow in, for example, heart failure patients.

An electroanatomical mapping system can map electrical activation of tissue, and in particular create a slow conduction map, using a plurality of electrophysiology data points, each including local activation timing information, by computing a slow conduction metric for each point using the local activation timing information. The slow conduction metric can be used to classify points as no conduction points, slow conduction points, and normal conduction points, and the results can be graphically expressed, including as an animated representation of an activation wavefront propagating along a three-dimensional anatomical surface model.

A pressure guidewire is provided that includes an outer tube, a connector tube positioned radially inward of the outer tube, a pressure sensor assembly, and/or a distal tip at the distal end of the outer tube. A core wire may be positioned distal to the connector tube. The core wire may have a reduced diameter portion such as a tapered portion. The pressure sensor assembly may include a pressure sensor positioned distal of the connector tube, for example radially between a coil portion of the outer tube and the core wire. The pressure sensor assembly may also include one or more pressure wires leads extending from the pressure sensor and through the connector tube lumen.

A medical system is provided. The medical system includes a processing device communicatively coupled to a probe. The processing device operates to cause the medical system receive physiological signals from electrodes of the probe and decompose the physiological signals into near-field component and far-field component by using mutual information from a set of the electrodes. The processing device operates to cause the medical system utilize the near-field components for localizing in time where a wave went under at least one of the plurality of electrodes.