Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a finger clip having a roller ring or wheel rotatably mounted thereto is disposed within an inflatable membrane. The roller ring can include a measurement pattern positioned opposite to optical fibers configured to receive light reflected from the measurement pattern. A user can put on the finger clip, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the inside of the membrane, which is pressed against the rectal wall, the roller ring can rotate with respect to the fibers such that the fibers move relative to the measurement pattern. A controller can sense light reflected through the fibers from the reference pattern and calculate or estimate various attributes of the prostate based on the reflected light.

An ingestible device is disclosed which can produce spectral data of one or more analytes, as well as associated methods for characterizing the gastrointestinal tract of a subject which contains such analytes. Related kits and systems are also disclosed.

The invention includes a wireless multifunction veterinary thermometer device that communicates with a mobile communication device running an app for recording animal temperature data and to display animal treatment options considering the recorded data and ambient weather conditions. Treatment options may be determined by logic programmed within the app or by another computer program associated with a remote server and database. Data transfer takes place between the mobile device and the remote server/database. A heat stress indicator is displayed for the user. If the indicator represents a high heat stress level, the app logic or remote computer program may automatically generate a recommended treatment option, or the user may determine an appropriate treatment.

An integrated physiological monitoring and tissue anchoring device is provided. The device includes a detachable clamp at the distal portion that includes a sensor configured to sense a physiological parameter from the gastrointestinal tract. A handle at the proximal portion of the device is configured to actuate the clamp into a closed configuration in which gastrointestinal tissue is grasped by the clamp. A cable connects the handle to the clamp and has a frangible section near the clamp such that the clamp is detachable from the cable at the frangible section.

Endoscopic and self-deploying gastrointestinal suture retention systems are provided herein. Such systems provide prolonged residency in the gastrointestinal tract for chronic physiological monitoring or controlled drug release in the gastrointestinal tract. A self-deploying system includes a substrate, sensor and torsion springs and an endoscopic system includes a tubular device that includes detachable components at the distal portion thereof.

A device (1) for measuring congestion of the digestive tract comprises at least one housing (2), a current generator (30) and a means (31) for measuring a difference in potential, said generator and means being accommodated in said housing, and a set of electrodes (3) comprising at least two electrodes connected electrically, independently of one another, to the current generator (30) and/or to the means (31) for measuring a difference in potential across the terminals of the electrodes, each electrode of the set (3) of electrodes being configured to transmit an electric current and/or to allow a difference in electrical potential to be measured.

The set (3) of electrodes is configured to generate at least one electric current flow loop (13) flowing at least through a tissue of the gastrointestinal tract (14) of the user and to allow a difference in electrical potential in relation to the tissue of the gastrointestinal tract to be measured, the device (1) for measuring the bio-impedance of the digestive tract further comprising a calculating module (5) configured to receive the measured difference in electrical potential and to calculate a value of the bio-impedance of the digestive tract according to this measurement in relation to the tissue of the digestive tract.

An apparatus for intraoperative neuromonitoring of nerves in the pelvic region of a patient, having at least one nerve stimulator which can be introduced into the operating area during an operation, and a sensor device which can be attached to at least one pelvic organ of the patient. In order to provide an apparatus of this type, by means of which it is possible to reliably monitor, without a significant delay, the integrity/proper functioning of nerves which act on one or more pelvic organs, i.e. in particular the bladder and/or the rectum, during an operation in the pelvic region of a patient, the sensor device includes at least two sensing electrodes, which can be applied to the pelvic organs, and an impedance measuring device, which is or can be connected to the sensing electrodes and has a display showing impedance changes in the pelvic organs between the sensing electrodes. The stimulation of nerves which are connected to a pelvic organ such as the bladder or the rectum leads to changes in the complex electrical resistance (impedance) in the organ tissues in question, which can act as an indicator of the integrity of a nerve stimulated by the nerve stimulator.

A drug delivery device includes a capsule, a logic circuit disposed within the capsule, and an actuator connected to the logic circuit and configured to expose an interior of the capsule to an exterior of the capsule upon activation by the logic circuit.

In at least one embodiment of a device configured for insertion into a gastrointestinal tract of the present disclosure, the device comprises a core comprising a core material which is solid, semi-solid or compressible, one or more sensors embedded in an interior of the device and/or on a surface of the device, at least one of the one or more sensors configured to obtain a pressure measurement within the gastrointestinal tract and during defecation of the device, and a plurality of electrodes within or upon the device and configured to obtain impedance planimetric measurements within the gastrointestinal tract and during defecation of the device, the impedance planimetric measurements useful to determine cross-sectional areas.

Embodiments relate to an implantable device for detecting leakage of matter from a mammalian lumen, the device comprising a mesh structure that is attachable to a lumen of a mammalian. The mesh structure comprises a material or a material composition that is electrically conductive and which is measurably responsive in terms of its electrical conductivity when being subjected to leakage of matter from the lumen.