Described herein is an implantable medical device that includes a body having one or more ultrasonic transducers configured to receive ultrasonic waves and convert energy from the ultrasonic waves into an electrical energy, two or more electrodes in electrical communication with the ultrasonic transducer, and a clip attached to the body that is configured to at least partially surround a nerve and/or a filamentous tissue and position the two or more electrodes in electrical communication with the nerve. In certain examples, the implantable medical device includes two ultrasonic transducers with orthogonal polarization axes. Also described herein are methods for treating incontinence in a subject by converting energy from ultrasonic waves into an electrical energy that powers a full implanted medical device, and electrically stimulating a tibial nerve, a pudendal nerve, or a sacral nerve, or a branch thereof, using the fully implanted medical device.

Aspects of the disclosure relate to pledget stimulation/recording electrode assemblies that are particularly useful for automatic periodic stimulation. Embodiments are compatible with nerve monitoring systems to provide continuous stimulation of a nerve during surgery. Disclosed embodiments include an electrode assembly having one or more electrodes rotatably supported by and positioned within a pledget substrate. The flexible pledget substrate conforms and fixates to bioelectric tissue to secure the electrode assembly in position, wrapped around the target tissue. In some embodiments, the pledget substrate includes two bodies, each including at least one electrode, the two bodies being selectively separable so that the bodies can be repositioned with respect to one another. The electrode assembly further includes a lead wire assembly including at least one insulating jacket positioned around a wire core. Optionally, the electrode assembly includes an insulating cup interconnecting the electrode and the insulating jacket.

Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.

A method for fabricating electrodes sized and dimensioned to record, measure, and/or stimulate very fine nerve structures (e.g., microscale or less) is described herein. The method can include securing a tip of an electrode, comprising a conductor substantially encased by an insulator, to a proximal portion of an inserter. The electrode can be wound around a proximal portion of the inserter and a portion of the electrode can be secured to a distal portion of the inserter. A tension in the electrode can be maintained during the winding to keep the electrode in place during the winding.

An implantable device, or an associated computer program, for estimating a nerve conduction velocity. A stimulus is applied from one or more stimulus electrodes to a nerve. A digitised neural measurement of at least one compound action potential evoked by the at least one stimulus is obtained from one or more recording electrodes by measurement circuitry. The digitised neural measurement comprises a plurality of data sample points. The digitised neural measurement is processed in order to estimate within subsample precision a temporal position of a feature of interest of the compound action potential. From the estimated temporal position of the feature of interest, and from a propagation distance, a conduction velocity of the compound action potential is determined.

An adjustment aid includes a first adjustment electrode assembly having an excitation electrode and an evaluation electrode, a second adjustment electrode assembly having a reception electrode and a transmission electrode, and a control and evaluation circuit connected to the first adjustment electrode assembly. The first adjustment electrode assembly is arranged on the first component. The second adjustment electrode assembly is arranged on the second component. The control and evaluation circuit supplies the excitation electrode with an excitation signal and taps a measurement signal at the evaluation electrode. The measurement signal depends on a degree of overlap between the first adjustment electrode assembly and the second adjustment electrode assembly.

A nerve mapping system includes an energy based dissection device, a plurality of beacons, and a processing device. The plurality of beacons are disposed in a tissue of a patient. Each beacon is adapted to transmit one or more first electrical signals within the body and receive one or more second energy signals. The processing device is adapted to determine first locations associated with the plurality of beacons, a second location associated with the energy based dissection device, and a third location associated with a nerve within the tissue, based on the one or more second signals, generate a mapping of the first locations, second location, and third location, and cause the first locations, second location, and third location to be displayed on a display device.

A shield member is placed within a polymer flexible carrier in between a manipulation member used to aid implant of a nerve cuff and the nerve to avoid touching the nerve surface with the manipulation member because the texture or material of the flexible member typically causes more foreign body reaction or other biologic reaction from the nerve and surrounding tissues than the polymer of the flexible carrier itself.

Provided is a catheter including a shaft having a distal end and a loop disposed near the distal end and configured to curl around a tissue and receive, via the shaft, energy to denervate at least a portion of the tissue. The loop includes: a first film capable of bending to curl around the tissue; a plurality of electrodes disposed on the first film and arranged in parallel to each other with a predetermined distance; a sensor disposed at a position corresponding to a position between the plurality of electrodes.

Systems and related methods for identifying and/or ablating targeted nerves are provided. A probe with stimulating electrodes and/or ablation members are provided. The probe may be inserted into a nasal cavity and current may be introduced through the electrodes to stimulate a targeted area. The response to stimulation may be used to identify the targeted nerve. Once identified, the ablation member may ablate the targeted nerve.