A subcutaneously implantable device includes a housing, a clip attached to the housing that is configured to anchor the device to a muscle, a bone, and/or a first tissue, and circuitry in the housing that is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to an organ, a nerve, the first tissue, and/or a second tissue. The circuitry includes a first power source, and a transceiver. A first antenna on the device is in electrical communication with the first power source. The first antenna is configured to be subcutaneously positioned in a patient. A second antenna on the device is in electrical communication with the transceiver. The second antenna is configured to be subcutaneously positioned in the patient.

A method of subcutaneously injecting and anchoring a device to a bone, a muscle, and/or a first tissue in a patient, the device having a clip configured to anchor the device to the bone, the muscle, or the first tissue, includes making an incision in the patient; inserting and advancing a first surgical instrument that spreads a second tissue to form a tunnel therein; inserting an insertion device loaded with the device through the incision; advancing the insertion device through the tunnel to the bone, the muscle, and/or the first tissue upon which the device is to be anchored; and anchoring the device to the bone, the muscle, and/or the tissue using the clip on the device

A delivery system for an intracorporeal device includes a sheath defining one or more lumens shaped to receive a delivery catheter or shaft and a guidewire. The system may include a delivery shaft having a distal coupling feature adapted to releasably couple with a proximal coupling feature of the intracorporeal device. The delivery system may further include a hub through which the delivery shaft and guidewire are passed. The delivery shaft may be coupled to a feature, such as a knob, that enables manipulation of the delivery shaft to decouple the distal fixation feature from the proximal fixation feature of the intracorporeal device in order to deploy the intracorporeal device within a patient.

A glucometer for monitoring blood glucose comprises a curved test surface with a transparent test site. The curved test surface accommodates a finger-tip and an enclosing lid encloses the finger-tip when it is placed on the transparent test site. The glucometer further comprises a light source assembly comprising light emitting diodes, underneath the transparent test site. The glucometer further comprises detectors for detecting transflective light, transmissive light, and reflective light from blood capillaries at a depth of 100 micro meters below skin surface. The glucometer further comprises a software module comprising a first sub-module that comprises a first set of algorithms for generating a data matrix. The transflective, transmissive light, and reflective light from blood capillaries are measured and recorded in data matrix. A second sub-module comprises a second set of algorithms for non-invasive measurement of concentration of glucose in the blood by processing data within the data matrix.

An endoscopic surgical instrument includes an elongated shaft and a pair of elongated arms extending through the shaft. The arms have a distal end portion configured to grasp tissue therebetween. The distal end portion of at least one of the arms is equipped with a sensor for sensing a property of the tissue.

Described herein is an implantable medical device that includes a body having one or more ultrasonic transducers configured to receive ultrasonic waves and convert energy from the ultrasonic waves into an electrical energy, two or more electrodes in electrical communication with the ultrasonic transducer, and a clip attached to the body that is configured to at least partially surround a nerve and/or a filamentous tissue and position the two or more electrodes in electrical communication with the nerve. In certain examples, the implantable medical device includes two ultrasonic transducers with orthogonal polarization axes. Also described herein are methods for treating incontinence in a subject by converting energy from ultrasonic waves into an electrical energy that powers a full implanted medical device, and electrically stimulating a tibial nerve, a pudendal nerve, or a sacral nerve, or a branch thereof, using the fully implanted medical device.

A medical instrument is provided and includes a housing and a shaft coupled to the housing. The shaft has a proximal end and a distal end. An end-effector assembly is disposed at the distal end of the shaft. The end-effector assembly includes first and second jaw members. At least one of the first and second jaw members is movable from a first position wherein the first and second jaw members are disposed in spaced relation relative to one another to at least a second position closer to one another wherein the first and second jaw members cooperate to grasp tissue therebetween. The medical instrument also includes one or more light-emitting elements and one or more light-detecting elements configured to generate one or more signals indicative of tissue florescence. The one or more light-emitting elements are adapted to deliver light energy to tissue grasped between the first and second jaw members.

This medical device measures blood flow rate through the renal artery after a kidney transplant in real time. The device utilizes a force sensing resistor (FSR) to detect the amount of blood and the given blood pressure at any instantaneous point in time. The FSR wraps around the renal artery after transplantation and should remain connected for five to seven days for optimal kidney blood flow and kidney functioning detection. This will be achieved by measuring the flow rate, estimating blood pressure, and beats per minute this device should alert doctors if irregular kidney function should occur for fast and immediate surgical or bedside intervention. Our goal is to detect post-transplant kidney rejection in real-time. The device is biocompatible and sterile, easily removed from the renal artery, and smaller than 5 mm in diameter.

Systems and methods for estimating anatomic alignment between two or more bones are described herein. An example method can include registering an anatomic reference frame. Additionally, the method can include establishing a respective rotational relationship between each of one or more bones and an orientation sensor attached to each of the one or more bones. The method can also include receiving, from each of the orientation sensors, orientation information, and then calculating an orientation of a bone relative to the anatomic reference frame. The method can further include calculating, using the respective orientations of the bones relative to the anatomic reference frame, an anatomic alignment parameter between first and second bones.

A sensor module retaining device having a first portion, a second portion, and a third portion. The first portion defines an open loop that is sized and configured to contour around an outer surface of a blood vessel. The second portion is opposite the third portion and the second and third portions each extend distally away from the open loop and define an open channel therebetween. The second and third portions are contiguous with and converge inwards towards the first portion.