A61B5/7257

Magnetic resonance spectroscopy pulse sequence, acquisition, and processing system and method

Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.

Medical imaging and efficient sharing of medical imaging information

An MRI image processing and analysis system may identify instances of structure in MRI flow data, e.g., coherency, derive contours and/or clinical markers based on the identified structures. The system may be remotely located from one or more MRI acquisition systems, and perform: error detection and/or correction on MRI data sets (e.g., phase error correction, phase aliasing, signal unwrapping, and/or on other artifacts); segmentation; visualization of flow (e.g., velocity, arterial versus venous flow, shunts) superimposed on anatomical structure, quantification; verification; and/or generation of patient specific 4-D flow protocols. A protected health information (PHI) service is provided which de-identifies medical study data and allows medical providers to control PHI data, and uploads the de-identified data to an analytics service provider (ASP) system. A web application is provided which merges the PHI data with the de-identified data while keeping control of the PHI data with the medical provider.

Systems and methods for identifying biological structures associated with neuromuscular source signals

A system comprising a plurality of neuromuscular sensors, each of which is configured to record a time-series of neuromuscular signals from a surface of a user's body; and at least one computer hardware processor programmed to perform: applying a source separation technique to the time series of neuromuscular signals recorded by the plurality of neuromuscular sensors to obtain a plurality of neuromuscular source signals and corresponding mixing information; providing features, obtained from the plurality of neuromuscular source signals and/or the corresponding mixing information, as input to a trained statistical classifier and obtaining corresponding output; and identifying, based on the output of the trained statistical classifier, and for each of one or more of the plurality of neuromuscular source signals, an associated set of one or more biological structures.

Multiple frequency scanning using an ultrasound probe
11596381 · 2023-03-07 · ·

A system may include an ultrasound probe and a controller unit configured to communicate with the ultrasound probe. The controller unit may be further configured to transmit ultrasound signals using the ultrasound probe toward an area of interest in a patient's body, wherein the ultrasound signals include a fundamental frequency signal and at least one harmonic frequency signal; receive echo signals from the area of interest based on the transmitted ultrasound signals; obtain a fundamental frequency echo signal and at least one harmonic frequency echo signal from the received echo signals; and generate a visual representation of the area of interest based on the obtained fundamental frequency echo signal and the obtained at least one harmonic frequency echo signal.

Remote sensing and measurement system using time-of-flight detectors
11596311 · 2023-03-07 · ·

A measurement system is provided with an array of laser diodes with one or more Bragg reflectors. At least a portion of the light generated by the array is configured to penetrate tissue comprising skin. A detection system configured to: measure a phase shift, and a time-of-flight, of at least a portion of the light from the array of laser diodes reflected from the tissue relative to the portion of the light generated by the array; generate one or more images of the tissue; detect oxy- or deoxy-hemoglobin in the tissue; non-invasively measure blood in blood vessels within or below a dermis layer within the skin; measure one or more physiological parameters based at least in part on the non-invasively measured blood; and measure a variation in the blood or physiological parameter over a period of time.

Methods for training a model for use in radio wave based blood pressure monitoring
11596321 · 2023-03-07 · ·

Methods for training a model for use in monitoring a health parameter in a person are disclosed. In an embodiment, a method involves monitoring a blood pressure of a person using a control blood pressure monitoring system, receiving control data that corresponds to the monitoring using the control blood pressure monitoring system, receiving stepped frequency scanning data that corresponds to radio waves that have reflected from blood in a blood vessel of the person, wherein the stepped frequency scanning data is collected through multiple receive antennas over a range of frequencies, generating training data by combining the control data with the stepped frequency scanning data in a time synchronous manner, and training a model using the training data to produce a trained model, wherein the trained model correlates stepped frequency scanning data to values that are indicative of a blood pressure of a person.

Method of monitoring respiratory rate in a health monitoring device

This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.

Measurement of vital signs based on images recorded by an egocentric camera
11596315 · 2023-03-07 · ·

A method for determining one or more vital signs of a person includes recording video images of a scene with an egocentric camera coupled to the person's body, detecting and magnifying image frame-to-image frame movements in the video images of the scene, representing the magnified image frame-to-image frame movements in the video images of the scene by a one-dimensional (1D) amplitude-versus-time series, and transforming the 1D amplitude-versus-time series representation into a frequency spectrum. The method further includes identifying one or more local frequency maxima in the frequency spectrum as corresponding to one or more vital signs of the person.

MAGNETIC RESONANCE SPECTROSCOPY PULSE SEQUENCE, ACQUISITION, AND PROCESSING SYSTEM AND METHOD

Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.

SYSTEM AND METHOD FOR EVALUATING FEEDING MATURATION

A method for monitoring feeding maturation in premature babies, the method including measuring an acoustic response from a baby during a selected time period to provide acoustic information; comparing the measured acoustic response against a train data set to determine an indication of a swallow event; and measuring a respiration pattern of the baby during a swallow cycle using a peak and valley model to provide respiration data, where a feeding maturity of the baby is determinable in dependence on the swallow indication and respiration data.