A technique for predicting fluid responsiveness in a critically ill patient comprises measuring physiological data of the patient, then generating an estimate of pulse pressure variability from a Fourier transform of the physiological waveform. Both invasive and non-invasive physiological data measurements may be used.

Deoxyhemoglobin in a subject may be modulated to act as a contrast agent for use in magnetic resonance imaging. Sequential gas delivery may be applied to adjust the level of deoxyhemoglobin in the subject. A suitable magnetic resonance imaging (MRI) pulse sequence that is sensitive to magnetic field inhomogeneities, such as a blood-oxygen-level dependent (BOLD) sequence, may be used to detect deoxyhemoglobin as a contrast agent.

A smartphone plugin determines the heart rate and the breathing rate of a user, who is either holding the smartphone in his/her hand or who has the smartphone resting on his/her chest when lying in a supine position, using only smartphone accelerometer output data and no external sensors. The smartphone is preloaded with spectral entropy to weight mapping information for each of a plurality of use cases. The plugin performs frequency domain processing on accelerometer output data to determine an estimated heart rate EHR and an estimated breathing rate EBR. The spectral entropy of accelerometer output data is determined, and is used along with an appropriate spectral entropy to weight mapping, to determine an EHR weight for each EHR value and an EBR weight for each EBR value. The weights are used to adjust the EHR and EBR values to generate more accurate heart rate and breathing rate values.

One of the objectives of this invention is to allow the conduction of audiometric evaluations in natural or artificial sound spaces, in a way that can be monitored and reproduced.

For that purpose, the inventors propose to create virtual environments which reproduce sound and visual characteristics of natural or artificial spaces.

In practice, a user experience is initiated between a subject and a virtual environment so as to simulate a specific audiometry test. Finally, a spatial auditory localization score is determined from measurements that will be carried out in the virtual environment.

Data-stream bridging for sensor transitions is described. A first data stream of glucose measurements is received from a first glucose sensor worn by a user. A termination event for the first glucose sensor is detected when production and/or communication of the first glucose measurements via the first data stream ceases. Next, a second data stream of glucose measurements is received from a second glucose sensor worn by the user that replaces the first glucose sensor. During a warmup period for the second glucose sensor, estimated glucose values are output for the user based on both the first data stream of glucose measurements received from the first glucose sensor prior to the termination event and the second data stream of glucose measurements received from the second glucose sensor.

A motion data processing method and a motion monitoring system provided in the present disclosure may process an electromyography (EMG) signal in the frequency domain or time domain to identify an abnormal signal in the EMG signal, such as an abrupt signal, a missing signal, a saturation signal, an oscillation signal, etc. caused by a high-pass filtering algorithm. The motion data processing method and the motion monitoring system may further perform a data sampling operation on the EMG signal through a data sampling algorithm, and predict data corresponding to the time point when the abnormal signal appears based on the sampling data, so as to obtain prediction data, and replace the abnormal signal by using the prediction data to correct the abnormal signal. The motion data processing method and the motion monitoring system may not merely accurately identify the abnormal signal, but further correct the abnormal signal, so that the corrected data may be more in line with an actual motion of a user, thereby improving user experience.

A method including the steps of receiving a first signal sensed from a patient, receiving a first physiological signal sensed from the patient, and processing the first signal based at least on the first physiological signal to obtain a second signal that is a measurement of the patient's Heart Rhythm.

A method for detecting cardiac arrhythmia based on a photoplethysmographic (PPG) signal is provided. The method includes: receiving a PPG signal and a motion signal corresponding to a motion made by a user; extracting PPG signal segments and motion signal segments corresponding to a time period from the PPG signal and the motion signal, respectively, at every time period; filtering out motion artifact noise in the PPG signal segments according to the PPG signal segments and the motion signal segments, and converting the PPG signal segments and the motion signal segments into PPG spectrum diagrams and motion spectrum diagrams, respectively; obtaining an estimated heart rate according to the PPG spectrum diagrams and the motion spectrum diagrams; and determining whether cardiac arrhythmia is present based on the filtered PPG signal segments and the estimated heart rate.

A wearable medical includes a walking detector module with a motion sensor that is configured to detect when the patient is walking or running. In embodiments, a parameter (referred to herein as a “Bouncy” parameter) is determined from Y-axis acceleration measurements. In some embodiments, the Bouncy parameter is a measurement of the AC component of the Y-axis accelerometer signal. This detection can be used by the medical device to determine how and/or whether to provide treatment to the patient wearing the medical device. For example, when used in a WCD, the walking detector can prevent “false alarms” because a walking patient is generally conscious and not in need of a shock.

A device for monitoring a health parameter in a person is disclosed. The device includes a semiconductor substrate, at least one transmit antenna configured to transmit millimeter range radio waves over a 3D space below the skin surface of a person, multiple receive antennas configured to receive radio waves, the received radio waves including a reflected portion of the transmitted radio waves, wherein the semiconductor substrate includes circuits for processing signals received on the multiple receive antennas, wherein processing signals includes mixing signals of two different frequencies, and wherein the semiconductor substrate includes at least one output configured to output a signal that corresponds to a health parameter of a person in response to received radio waves.