A braided implant is provided that can secure within an aneurysm sac, occlude a majority of the aneurysm's neck, and at least partially fill the aneurysm sac. The implant can include a tubular braid that can be set into a predetermined shape, compressed for delivery through a microcatheter, and implanted in at least one implanted position. In some examples, the tubular braid can be implanted in two distinct implanted shapes, allowing for treatment of a wide range of aneurysm sizes. In some examples, the implanted braid can include a compaction resistant column spanning the height of the aneurysm.

There is described an endovascular prosthesis delivery device. The subject endovascular prosthesis delivery device comprises a combination of a delivery frame element and a hub insert element that are secured to one another by a first retention element. At a distal portion of the delivery frame element, there is a prosthesis attachment zone for coupling to an endovascular prosthesis. When it is desired to deploy the endovascular prosthesis, the first retention element is broken in a manner to allow relative movement between the hub insert element and the delivery frame element. A pull wire assembly is secured with respect to the hub insert element and comprises a pull wire which is coupled to the endovascular prosthesis in the prosthesis attachment zone of the delivery frame element. Once the first retention element is broken by the physician (this is done when the endovascular prosthesis is in the correct position for deployment), the physician can then retract the hub insert which has the effect of retracting pull wire from the prosthesis attachment zone of the delivery frame element. The endovascular prosthesis and the endovascular prosthesis delivery device are now detached from one another and the latter may be withdrawn from the patient.

Vascular delivery systems configured to deliver an implant to a location within a vasculature can include one or more control wires controllable by a user to detach the implant from the delivery system. Control wires can cause a feature of the delivery system to mechanically engage a hub at a proximal end of an implant. Proximal or distal movement of the control wire can allow the feature to disengage from the hub, thereby allowing release of the implant.

An intravascular delivery device is disclosed comprising a delivery wire having a proximal and a distal end and an interior lumen extending there between and wherein said distal end comprises a connection interface adapted to matingly interlock with a proximal end portion of a medical implantable device, wherein said delivery device comprises a locking unit arranged to secure said connection interface in a locking position in which said medical implant is pivotably locked before a controlled release.

A bristle device for delivery into a body lumen comprises a longitudinally extending stem 1 and a plurality of bristles extending generally outwardly from the stem for anchoring the device in a body lumen. There may be at least two bristle segments and in some cases there are flexible sections between the segments. The flexible sections articulate to enable the device to pass through a catheter placed in a tortuous anatomy or to be deployed in a curved vessel, or across a bifurcation. In some cases at least some of the bristle segments are spaced-apart to accommodate bending of the bristles.

An in-tube transit object that is inserted in a tube includes: a coil section formed by winding a wire; and a fiber section attached to an end on one side and an end on the other side in a winding-axis direction of the coil section. The coil section is formed with a large diameter section, through which fiber of the fiber section is inserted, at the end on the one side and the end on the other side, and is inserted in an extending state in the winding-axis direction when the in-tube transit object is inserted into the tube. The fiber section is configured to expand when seen in the winding-axis direction in the case where the in-tube transit object is inserted in the tube and then discharged from the tube, which brings the coil section into a compressed state in the winding-axis direction.

Disclosed are embodiments of a method for occluding a left atrial appendage (LAA) and other cavities or openings within a body. Some embodiments of the method can include an implant configured to be deployed within the LAA or other cavity, configured to be expanded or moved against a wall portion of the LAA or other cavity, and configured to twist at least a portion of the LAA or other cavity when the implant is rotated. Thereafter, one or more securing elements, staples, sutures, or other fasteners can be implanted in the gathered tissue to hold the tissue in the gathered state, thereby occluding the opening of the LAA or other cavity. In some embodiments, the opening of the LAA or other cavity can be occluded by elongating or otherwise reshaping the opening using an implant device, and securing the opening in the occluded state.

A device to treat a left atrial appendage (LAA) of a patient includes a tissue ingrowth member, at least one connector, a tine, and a plurality of struts connected to the tissue ingrowth member and at least one connector. A plurality of anchors extends from the tissue ingrowth member proximate the connection point of the struts to the tissue ingrowth member. The device is configured to change shape from a compressed pre-deployment configuration to at least one expanded post-deployment configuration such that the anchors puncture and lodge into cardiac tissue, occluding an ostium of the left atrial appendage.

Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.

A system for delivering a vascular implant into a body lumen including a vascular implant having a first engagement portion at a proximal portion and an elongated delivery member having a second engagement portion at a distal portion releasably engageable with the first engagement portion. An elongated member extends through the delivery member wherein in the extended position the elongated member extends into at least a portion of the implant to prevent release of the implant from the delivery member and in the retracted position the elongated member enables release of the implant from the delivery member.