Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements are attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, the handle assembly encapsulates an electric motor assembly, a pump assembly, and a controller assembly.

A removal device and a removal system are configured to effectively remove an object in a body lumen while suppressing damage to another device. The removal device includes an elongated shaft part, and a cutting part fixed to a distal portion of the shaft part. The proximal portion of the cutting part includes a ringshaped cutting blade, and a surface of the cutting part on which the cutting blade is positioned is inclined relative to center axis of the shaft part at an angle greater than 0 degrees and less than 90 degrees.

Described herein are atherectomy catheters, systems and methods that include a distal tip region that may be moved laterally so that its long axis is parallel with the long axis of the main catheter body axis. Displacing the distal tip region laterally out of the main catheter body axis exposes an annular blade and opens a passageway for cut tissue to enter a storage region within the catheter. The annular blade may be internally coupled to a drive shaft that rotates the blade, and thus the exposed blade edge may have the same crossing profile (OD) as the rest of the distal end region of the catheter. Also described herein are gear-driven atherectomy devices that may use a cable drive shaft to actuate the annular blade. Both push-to-cut and pull-to-cut variations are described, as are methods for cutting tissue and systems including these atherectomy catheters.

A medical device for cutting an object S in a body lumen is disclosed, which includes: a rotatable drive shaft; a tubular outer sheath configured to accommodate the drive shaft in a rotatable manner; a rotation structure, the rotation structure comprising an accommodation portion configured to be disposed inside the outer sheath; an exposed portion, the exposed portion being located at a distal side of the accommodation portion and is provided with a cutting portion, in which the accommodation portion is provided to be rotatable by the drive shaft, and a side surface of the accommodation portion and a side surface of the exposed portion have a groove portion, the groove portion extending from the accommodation portion to the exposed portion.

A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.

Systems and methods are provided for altering the shape of a target tissue structure of a subject, e.g., a nasal septum or other nasal tissue that include securing a first end of a shaping element to tissue adjacent the structure; manipulating the tissue to alter a shape of the structure; and applying a force to the shaping element to maintain the altered shape of the structure.

A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes. A tool is provided to aspirate excess fluid and tissue from the treatment area.

A medical device for cutting an object in a body lumen. The medical device includes a rotatable drive shaft; a tubular outer sheath configured to accommodate the drive shaft in a rotatable manner; and a rotation structure located on a distal side of the drive shaft, the rotation structure comprising: one or more rings; a cylindrical portion configured to be rotated by the drive shaft, the cylindrical portion having a side surface with a first groove portion; a cutting portion located on a distal side of the cylindrical member; the first groove portion is configured to pass through an inside of the one or more rings; and wherein the one or more rings is configured to rotate relative to the cylindrical portion of the rotation structure.

Described herein are atherectomy catheters, systems and methods that include a distal tip region that may be moved laterally so that its long axis is parallel with the long axis of the main catheter body axis. Displacing the distal tip region laterally out of the main catheter body axis exposes an annular blade and opens a passageway for cut tissue to enter a storage region within the catheter. The annular blade may be internally coupled to a drive shaft that rotates the blade, and thus the exposed blade edge may have the same crossing profile (OD) as the rest of the distal end region of the catheter. Also described herein are gear-driven atherectomy devices that may use a cable drive shaft to actuate the annular blade. Both push-to-cut and pull-to-cut variations are described, as are methods for cutting tissue and systems including these atherectomy catheters.

Described herein are methods using mechanical inverting tube apparatuses to remove clot (e.g., thrombectomy), the apparatuses including an inversion support catheter having an expandable funnel-shaped distal end, and a flexible tube that can be continuously rolled over the funnel-shaped distal end and invert into the inner lumen of the inversion support catheter.