An electroporation probe that includes an injection means, allowing a single electroporation probe to be used for both the electroporation of cells and the injection of a fluid. The electroporation probe having (a) a probe body having an interior channel, a first end, and a second end; (b) a plurality of perforations in the probe body proximal the second end; (c) a sleeve positioned within the interior channel, wherein the sleeve is moveable between a first position sealing the perforations and a second position opening the perforations; (d) a connection between the probe body and an electroporation machine, wherein the probe body is in electrical communication with the electroporation machine; and (e) a tubing in fluid communication with the interior channel, wherein fluid injected into a proximal end of the tubing is exitable through the perforations when the sleeve is in the second position.

The invention relates to a device, a system and a method for antimicrobial treatment during the performance of operations in bodies, a method for manufacturing the device as well as a computer program.

There is provided a device (11) for antimicrobial treatment during the performance of operations, in particular minimally invasive operations, in bodies. Said device comprises a base body (1) for partial introduction into a body and, furthermore, at least one plasma source (12) arranged in at least one portion of the base body (1). The plasma source (12) has at least one high-voltage electrode (9) which is at least partially covered and in particular completely covered with a dielectric (10), which high-voltage electrode is set up to produce a plasma by means of dielectric barrier discharge when an electrical voltage is applied and in conjunction with a second electrode.

A multi-cannula surgical instrument having an inner cannula movably disposed within an outer cannula, the inner cannula having a blunt distal tip, one or more first inner ducts and one or more first flow-through orifices arranged to allow one or more fluid flows therethrough, where the inner and the outer cannula at the proximal ends thereof are mounted onto a hub that includes a biasing mechanism coupled to the inner cannula and arranged to bias the inner cannula automatically from a retracted towards an advanced position in case of absence of resistance against the inner cannula, wherein the outer cannula comprises one or more second flow-through orifices that are in fluid communication with one or more second ducts arranged between the outer and the inner cannula, wherein the second flow-through orifices, the hub and the second ducts are configured to allow at least one fluid flow therethrough.

Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).

A dilation introducer for orthopedic surgery is provided for minimally invasive access for insertion of an intervertebral implant. The dilation introducer may be used to provide an access position through Kambin's triangle from a posterolateral approach. A first dilator tube with a first longitudinal axis is provided. A second dilator tube may be introduced over the first, advanced along a second longitudinal axis parallel to but offset from the first. A third dilator tube may be introduced over the second, advanced along a third longitudinal axis parallel to but offset from both the first and the second. An access cannula may be introduced over the third dilator tube. With the first, second, and third dilator tubes removed, surgical instruments may pass through the access cannula to operate on an intervertebral disc and/or insert an intervertebral implant.

A dilation introducer for orthopedic surgery is provided for minimally invasive access for insertion of an intervertebral implant. The dilation introducer may be used to provide an access position through Kambin's triangle from a posterolateral approach. A first dilator tube with a first longitudinal axis is provided. A second dilator tube may be introduced over the first, advanced along a second longitudinal axis parallel to but offset from the first. A third dilator tube may be introduced over the second, advanced along a third longitudinal axis parallel to but offset from both the first and the second. An access cannula may be introduced over the third dilator tube. With the first, second, and third dilator tubes removed, surgical instruments may pass through the access cannula to operate on an intervertebral disc and/or insert an intervertebral implant.

A dilation introducer for orthopedic surgery is provided for minimally invasive access for insertion of an intervertebral implant. The dilation introducer may be used to provide an access position through Kambin's triangle from a posterolateral approach. A first dilator tube with a first longitudinal axis is provided. A second dilator tube may be introduced over the first, advanced along a second longitudinal axis parallel to but offset from the first. A third dilator tube may be introduced over the second, advanced along a third longitudinal axis parallel to but offset from both the first and the second. An access cannula may be introduced over the third dilator tube. With the first, second, and third dilator tubes removed, surgical instruments may pass through the access cannula to operate on an intervertebral disc and/or insert an intervertebral implant.

A dilation introducer for orthopedic surgery is provided for minimally invasive access for insertion of an intervertebral implant. The dilation introducer may be used to provide an access position through Kambin's triangle from a posterolateral approach. A first dilator tube with a first longitudinal axis is provided. A second dilator tube may be introduced over the first, advanced along a second longitudinal axis parallel to but offset from the first. A third dilator tube be introduced over the second, advanced along a third longitudinal axis parallel to but offset from both the first and the second. An access cannula may be introduced over the third dilator tube. With the first, second, and third dilator tubes removed, surgical instruments may pass through the access cannula to operate on an intervertebral disc and/or insert an intervertebral implant.

A dilation introducer for orthopedic surgery is provided for minimally invasive access for insertion of an intervertebral implant. The dilation introducer may be used to provide an access position through Kambin's triangle from a posterolateral approach. A first dilator tube with a first longitudinal axis is provided. A second dilator tube may be introduced over the first, advanced along a second longitudinal axis parallel to but offset from the first. A third dilator tube may be introduced over the second, advanced along a third longitudinal axis parallel to but offset from both the first and the second. An access cannula may be introduced over the third dilator tube. With the first, second, and third dilator tubes removed, surgical instruments may pass through the access cannula to operate on an intervertebral disc and/or insert an intervertebral implant.

An energy delivery probe and method of using the energy delivery probe to treat a patient is provided herein. The energy delivery probe has at least one probe body having a longitudinal axis and at least a first trocar and a second trocar. Each trocar comprises at least two electrodes that are electrically insulated from each other, and each electrode is independently selectively activatable. An insulative sleeve is positioned in a coaxially surrounding relationship to each of the first trocar and the second trocar. The probe also has a switching means for independently activating at least one electrode. The method involves independently and selectively activating the first and second electrodes to form an ablation zone, then repeating the ablation by delivering energy to a second set of electrodes, producing one or more overlapping ablation zone, and eliminating the need to reposition the ablation probes.