Methods, systems and devices for treating a patient include providing a tissue treatment element constructed and arranged to deliver energy to tissue and treating tissue of the gastrointestinal tract by causing the tissue treatment element to deliver energy to an energy delivery zone. Treatment results in a reduction in the luminal surface area of at least a portion of the gastrointestinal tract. In particular embodiments, the methods, systems and devices are used to treat diabetes.

The invention provides systems and method for the removal of diseased cells during surgery.

Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

A lens system includes: a plurality of aligned lenses; a first lens having negative refractive power; a second lens having negative refractive power; a third lens with positive refractive power; and, a fourth lens with positive refractive power; a light beam transmitted through the first, second, third and fourth lenses is first diverged by the first and second lenses, collimated by the third lens and focused by the fourth lens to form a small spot at the focal plane.

The present invention provides a surgical access port, a positioning system for determining the three-dimensional pose of the surgical access port, and a laser cutting surgical system capable of aligning the laser beam based on the three-dimensional pose of the surgical access port. In particular, the invention is suited for robot-assisted surgical interventions.

The present invention provides methods and devices for shaped pulse laser lithotripsy to provide a high ablation rate while also minimizing retropulsion of the ablation products. A method and laser system for treating calculi in a human or animal body, comprising: a laser emitting a sequence of laser pulses, the laser being operable in an amplitude-modulation regime in which the laser pulses are emitted: at a constant pulse frequency, and with a periodically varying peak power or pulse energy or peak power and pulse energy with an amplitude modulation period Na equal to the number of pulses in an amplitude periodic group of pulses.

A laser device for skin ablation treatment. The device includes a laser source (5) and a handpiece (9). The laser beam has a Gaussian distribution of the power density to obtain different effects in the various regions exposed to the laser beam.

A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided apparatus for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.

Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.