Provided are a BG monitoring method and a PPG-based BG monitoring device for same in which a reference sample is prepared by means of preparing a human body substitute dummy and reference blood from which BG is removed and applying quasi-blood to the dummy, the signal amount of each wavelength band with respect to the reference sample to which the reference blood is applied is measured by means of a BG monitoring device, reference signal amount data is obtained and provided as basic data, irradiation light of a plurality of light sources is radiated on a body part of a subject for BG monitoring by means of the BG monitoring device of the present invention, a light-receiving element receives reflected light and scattered light and thus the signal amount of each wavelength band is obtained, a differential signal amount for each wavelength band, which is a corresponding reference signal amount for each wavelength band comprised in the basic data subtracted from the signal amount for each wavelength band with respect to the body part of the subject for BG monitoring, is obtained, and a BG amount corresponding to the differential signal amount for each wavelength band is calculated by means of the correlation between the differential signal amount for each wavelength band and the BG amount.

This invention relates to a method of calibrating a direct neural interface with continuous coding. The observation variable is modelled by an HMM model and the control variable is estimated by means of a Markov mixture of experts, each expert being associated with a state of the model.

During each calibration phase, the predictive model of each of the experts is trained on a sub-sequence of observation instants corresponding to the state with which it is associated, using an REW-NPLS (Recursive Exponentially Weighted N-way Partial Least Squares) regression model.

A second predictive model giving the probability of occupancy of each state of the HMM model is also trained during each calibration phase using an REW-NPLS regression method. This second predictive model is used to calculate Markov mixture coefficients during a later operational prediction phase.

An automated calibration system that includes a probe guide and a target assembly. The probe guide receives an optical probe, and the target assembly includes one or more calibration targets. The target assembly is slideable relative to the probe guide so that a first calibration target is aligned under the optical probe in a first position of the target assembly and a second calibration target is aligned under the optical probe in a second position of the target assembly.

In one embodiment, an apparatus for calibrating a probe that includes an image sensor and a magnetic field sensor, includes a jig configured to hold the probe, a magnetic field generator configured to generate at least one magnetic field having a predefined direction in alignment with the jig, an optical target aligned with the jig so that the image sensor in the probe is able to capture an image of the optical target while the probe is held in the jig, and processing circuitry configured to receive from the probe a signal output by the magnetic field sensor in response to the at least one magnetic field and the image captured by the image sensor while the probe is held in the jig, and to calibrate an alignment of the image sensor relative to the magnetic field sensor responsively to the received signal and the received image.

An oximeter can include a sensor and a processor. The processor can access signal information corresponding to a test signal. The signal information can correspond to a characteristic. The characteristic can be determined using at least one of an AC component and a DC component. The processor can compare the characteristic and a reference value. The processor can adjust the signal, based on the comparison, to set a relationship between the characteristic and the reference value.

An oxygen saturation measuring apparatus capable of measuring arterial blood oxidation saturation (SpO2), and tissue oxygen saturation (rSO2), safely, easily and economically at a desired position of a biological body for a long time continuously. A ROM stores the distance information between a light emitting unit and a light receiving unit situated corresponding to the depth of a target intended to be measured for tissue oxygen saturation, a light emission driving unit makes the light emitting unit emit light in an amount of light corresponding to the distance information, MPU makes the light emitting unit emit a pulses capable of measuring the tissue oxygen saturation, MPU applies pulse capable of measuring the tissue oxygen saturation from the light emission driving unit to the light emitting unit, and the pulse increasing unit increases the amount of pulses from MPU for a predetermined time to pulses capable of measuring the arterial blood oxygen saturation.

A system for imaging and examination of a cervix, comprising a control module connectable with a changeable head configured to image the cervix and collect a tissue biopsy, the head selected from a group consisting of a digital colposcope module, a transvaginal optical probe module and an endo-cervical endoscope module. The system may additionally comprise light source(s) to illuminate cervix tissue; sensing device(s) to generate signal(s) from light and/or to acquire image(s) of a portion of a cervix; and processor(s) in communication with the sensing device(s). The system is configured to: (i) analyze the signal(s); (ii) detect the size of the cervix; (iii) determine parameters defining properties of the cervix; (iv) determine and distinguish normal tissue from abnormal tissue within the cervix; (v) determine the location of area(s) of abnormal tissue in the cervix; and (vi) generate a panoramic view of the cervix.

A system and method for depth-resolved imaging of fluorophore concentrations in tissue uses a pulsed light source stimulus wavelength to illuminate the tissue; and a time-gated electronic camera such as a single-photon avalanche detector camera to observe the tissue in multiple time windows after start of each light pulse. A filter device is between the tissue and the electronic camera with fluorescent imaging and stimulus wavelength settings. an image processor receives reflectance images and fluorescent emissions images from the time-gated camera and processes these images into depth and quantity resolved images of fluorophore concentrations in the tissue. Then image processor derives a fluorescence lifetime signal from the received temporal fluorescence signals and derives from these fluorescence lifetime signals biochemical property images of the tissue.

The present disclosure is generally related to systems and methods that can be implemented in a mobile application to allow users, such as parents and care providers, to measure and monitor, for example, a patient's body including an infant's head shape, at the point of care. The point of care can be, for instance, the home environment, a doctor's office, or a hospital setting. After acquiring 2D and/or 3D images of the body part, parameters reflecting potential deformity can be calculated. If abnormal measurements are determined, the user can be guided through therapeutic options to improve the condition. Based on the severity of the condition, different recommendations can be provided. Moreover, longitudinal monitoring and evaluation of the parameters can be performed. Monitoring of the normal child development can also be performed through longitudinal determination of parameters and comparison to normative values. Data can be shared with clinician's office.

The present invention provides a simulator device (1) mimicking human tissue for calibrating a medical or non-medical device (2). The simulator device (1) comprises at least one optically active foil (3a-d) for dynamically varying optical tissue properties, at least one skin-mimicking area (4a-d) arranged on top of said at least one optically active foil (3a-d), wherein said skin-mimicking area (4a-d) is arranged for receiving said medical or non-medical device (2) during said calibration, and wherein said at least one optically active foil (3a-d) is further configured for absorbing and reflecting light emitted by said medical or non-medical device (2) during said calibration depending on a voltage applied to said optically active foil (3a-d). The simulator device (1) further comprises at least one optical feedback sensor (5a-d) for measuring the optical response of said at least one optically active foil (3a-d), and a control unit (6) configured for controlling the voltage applied to said at least one optically active foil (3a-d) and for varying the applied voltage dependent on information from said at least one optical feedback sensor (5a-d).