An electronic device and method are disclosed herein. The electronic device includes a sensor and a processor. The processor implements the method, including measuring infrared light corresponding to a user using the sensor, and detecting biometric information of the user if the infrared information satisfies a predetermined condition.

A wearable physiological monitor is configured through a calibration procedure to provide a calibrated blood pressure measurement based on signals from an optical sensing system. In one aspect, optical (PPG) signals and motion signals are acquired while applying a mechanical stimulus over a range of mechanical frequencies with a haptic actuator. Resulting data is used to create a dynamic model for calculating blood pressure based on motion of the monitor. This blood pressure measurement can also usefully be correlated to the PPG signal for continuous blood pressure estimation. In another aspect, a monitoring device is positioned over a radial artery, and then optical measurements are taken of the radial artery while varying (and measuring) an applied force. Using various techniques, a model can be derived from this data for continuous blood pressure estimation.

A wearable physiological monitor is configured through a calibration procedure to provide a calibrated blood pressure measurement based on signals from an optical sensing system. In one aspect, optical (PPG) signals and motion signals are acquired while applying a mechanical stimulus over a range of mechanical frequencies with a haptic actuator. Resulting data is used to create a dynamic model for calculating blood pressure based on motion of the monitor. This blood pressure measurement can also usefully be correlated to the PPG signal for continuous blood pressure estimation. In another aspect, a monitoring device is positioned over a radial artery, and then optical measurements are taken of the radial artery while varying (and measuring) an applied force. Using various techniques, a model can be derived from this data for continuous blood pressure estimation.

A diagnostic apparatus (20) for detecting a presence of breast cancer in a patient disposed in a testing position. The diagnostic apparatus (20) includes a housing (44) and a camera assembly (58) that is supported by the housing (44) for recording images of the breasts of the patient. A rail (76) is supported by and extends from the housing (44) and terminates at a pair of rail ends (80). A trolley (88) interconnects the camera assembly (58) and the rail (76) and is slideable along said rail (76) for providing movement of the camera assembly (58) along the rail (76) between the rail ends (80) for allowing the camera assembly (58) to consecutively record images at different positions along the rail (76) and to record images of the lymph nodes of the patient when the camera assembly (58) is disposed adjacent to the rail ends (80) in alignment with the sides of the breasts of the patient.

The fluorescent light phantom device 1 is provided with: a phantom support 10 having fluorescent light phantom containers 1b, 1c, 1d and 1e; and fluorescent light phantoms 12, 13, 14 and 15 which are constituted of a medium that reproduces at least one of light scattering and light absorption of an object to be measured and a fluorescent coloring matter contained in the medium of a predetermined concentration and are stored in the fluorescent light phantom containers 1b, 1c, 1d and 1e.

An optical coherence tomography (OCT) system comprises: an imaging catheter; a calibration phantom removably arranged at least partially surrounding the distal end of the catheter; and a processor configured to control the catheter to acquire OCT images. The phantom has known dimensions and specific optical properties which provide non-changing calibration fiducials that span the imaging range of the system. The phantom is imaged by the catheter upon first connection to the system. The processor calculates a thickness of the phantom in the OCT image, and preforms z-offset calibration by setting the position of a phantom surface in the OCT image to a known nominal value. The known nominal value is related to one or more of the known thickness of the phantom or a diameter of the catheter sheath or a nominal angle of the light beam or the imaging range of the system.

Methods and devices are disclosed for calibrating intensity of a light source for evaluating a skin lesion using Elastic-Scattering Spectroscopy (ESS). The ESS system illuminates a skin lesion with a pulse from the light source adjusted to a high output setting, receives a signal comprising an elastic scattering spectrum from illuminating the skin lesion at the high output setting, determines whether the received signal has an intensity that is greater than a saturation threshold associated with at least one optical detection sensor, and if so, stores the elastic scattering spectrum. If less than the saturation threshold, the ESS system illuminates the skin lesion with a pulse from the light source adjusted to a low output setting, receives a signal comprising an elastic scattering spectrum from illuminating the skin lesion sample at the low output setting, and stores the elastic scattering spectrum at the low output setting.

A sleep tracker wearable device with ambient light artefact detection and removal when worn by a user comprises an optical sensor/emitter assembly, a spacer, and a controller. The optical sensor/emitter assembly includes an optical sensor with a sensor surface configured for receiving optical signals including ambient light. The spacer is disposed between the sensor surface of the optical sensor/emitter assembly and a skin surface of the user during operation, further for providing a given contact pressure and/or separation distance between the skin and sensor surfaces as a function of an adjustable height of the spacer. The controller controls at least one measurement modality of the sleep tracker wearable device. In addition, the controller is coupled to the optical sensor/emitter assembly (i) for detecting background lighting conditions based on the optical signals and (ii) for removing artefacts in the optical signals attributable to an external interaction with or perturbation of a natural progression of ambient lighting level.

Novel biophotonic phantoms are provided herein that can accurately mimic the optical properties of living tissue. The disclosed biophotonic phantoms comprise hemoglobin (Hb) in a native conformation that is distributed in a solid polymer matrix. Methods of producing the disclosed biophotonic phantoms are also provided. The biophotonic phantoms can be used, for example, to calibrate or test an optical imaging system, such as a near infrared spectroscopy imaging system.

Disclosed are methods for determining biometric indicators such as plasma volume, hematocrit and glomerular filtration rate, in mammalian subjects such as humans. The methods utilize a plurality of fluorescent tags having distinct fluorescent characteristics, which may be associated with a single static molecule, or wherein the static molecule is labeled with a fluorescent tag and a dynamic molecule is labeled with another fluorescent tag. One or more measurements of the intensities of the fluorescent emissions are taken subsequent to introduction of an injectate which contains the fluorescent tags, which can be taken using a probe or via a blood or plasma sample. Compositions and apparatuses for practicing the methods are also disclosed.