Additive manufacturing techniques are used to form an artificial intra-ocular lens (IOL) directly inside the human eye. Small openings are formed in the cornea and lens capsule of the eye, and the crystalline lens is broken up and removed through the openings; then, a material is injected into the lens capsule through the openings, and the focal spot of a pulse laser beam is scanned in a defined pattern in the lens capsule, to transform the material in the vicinity of the lase focal spot to form the IOL in a layer-by-layer manner. In one embodiment, stereolithography techniques are used where a pulse UV laser source is used to photosolidify a photopolymer resin. The liquefied resin is injected into the eye through the openings, after which only part of the resin, having the shape of the desired IOL, is selectively cured with the UV laser beam, via progressive layer formation.

A therapeutic method can include receiving an initial astigmatism condition of an eye; receiving a target final astigmatism condition of the eye; generating, based on the initial and target final astigmatism conditions, an eye incision pattern by iterating through a plurality of potential corrective combinations; and cutting the eye based on the eye incision pattern. Each of the potential corrective combinations can be defined by one or more of: an intraocular lens selected from a plurality of intraocular lens options, an access incision selected from a plurality of access incision options, and an arcuate incision selected from a plurality of arcuate incision options.

The present disclosure is directed to devices, systems, and methods directed to mounting a plunger tip to a plunger of an IOL injection device. A plunger tip wrench that is operable to releasably retain a plunger tip may be coupled to a holder extending from an end of the IOL injection device to align the plunger tip with the plunger of the IOL injection device. In some instances, the IOL injection device may include a motor and use a back electromotive force (EMF) of the motor to detect a position of the plunger as it is extended to engage the plunger tip. The plunger tip may be positioned relative to the plunger such that the plunger will engage the plunger tip within the entire range of a negative error position and a positive error position.

Canisters are provided that include a cylindrical body and a cap welded to the body to define a cavity filled with carbon dioxide or other fluid. The canisters may be loaded into a medical device, e.g., to provide an energy source for operating the device. Methods for making such canisters are also provided.

A capsular prosthesis is disclosed that is implanted to support posterior chamber placement of IOLs. The capsular prosthesis can be implanted to replace the capsule in situations where the patient's natural capsule has been rendered incapable of providing the structural support necessary to maintain proper centration of an IOL implanted therein. The prosthesis is surgically implanted into the eye by inserting the prosthesis into the eye through a primary incision. The prosthesis is secured to the sclera of the eye with at least two transscleral sutures to establish at least three points of contact between the sclera and the at least three apertures of the prosthesis. The at least two transscleral sutures support the sheet within a desired plane located within the posterior chamber, the plane containing a predetermined surgical axis passing through the center aperture. The IOL is inserted through the primary incision and optically captured on the prosthesis.

An ophthalmic implant configured for peri-operative, intra-operative, or post-operative assembly and disassembly. Drug delivery devices may be implanted with an intraocular lens, and later removed and replaced with new drug delivery devices.

The present invention relates to a prosthetic capsular bag and method for inserting the same. The prosthetic capsular bag helps to maintain the volume of the natural capsular bag, thereby stabilizing the effective lens position of an IOL so that refractive outcomes may be improved with cataract surgery. The prosthetic capsular bag further provides an integrated refractive surface, providing a means for experimentally determining an effective lens position prior to inserting an IOL.

The invention provides a device for secure support, storage and/or transport of a tissue graft or an implant, which allows for precise microscopic investigation and/or evaluation and quality control of the tissue graft or implant during processing as well as prior to introduction into a living body. The main body of the device is a cannula or a cartridge comprising rectangular shape, preferably with rounded edges, having two opposite openings of different sizes and shapes. The first opening has a round shape with a diameter suitable for connection to a tube or a syringe nozzle. The second opening has an elliptical, round, biconvex or rectangle shape, in the latter case preferably with rounded edges that is small enough to be inserted into a small surgical incision. The transparency and preferably rounded, rectangular shape of the main body of the device permits microscopic examination of the tissue graft or implant within the device, as well as secures the tissue graft or implant position during delivery and implantation. The elliptical, round, biconvex or preferably rounded rectangle inner shape of the second opening ensures the correct positioning of the tissue graft or implant during surgical implantation, thereby preventing issues such as loss of the tissue graft or implant orientation. The invention further provides assemblies for loading, storing and/or transporting a tissue graft or implant comprising the device according to the invention. The invention further provides a washing assembly and a method for preparing a tissue graft or implant.

Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An apparatus for delivery of a lens component into an eye, including: a nozzle; a housing, wherein the nozzle is operatively coupled to the housing; a first lever; a second lever; and a linkage assembly. The linkage assembly may be disposed within the housing between and adjacent to the first and second levers. The linkage assembly may include a plurality of linkages pivotably coupled to each other, wherein the linkage assembly is collapsible.

The invention relates generally to the use of dyes to enhance visualization of tissues and boundaries of openings in tissues during cataract surgery.