A catheter includes a positional identifier / marker at a tip section for a medical implant that needs to be aligned rotationally and/or axially and/or in terms of tilting in a human or animal body. The positional identifier is shaped and/or arranged such that a rotational orientation and/or an axial orientation and/or a tilted orientation of the tip section relative to the surrounding tissue is discernable from the position and/or orientation of the positional identifier

A system for heart valve repair includes a packaging assembly for storing the replacement heart valve. The packaging assembly includes a valve support having a base for holding the replacement heart valve, a ring positioned within the valve support and configured to fit around a circumference of the replacement heart valve, and a retention mechanism. The retention mechanism includes a cap and plurality of sutures configured to be attached to the cap and to the replacement heart. The packaging assembly having a locked configuration in which the ring and the valve support are locked together and the sutures tension the replacement heart valve. The packaging assembly is designed to hold and transport a replacement heart valve and fits within a shipment jar.

Some embodiments described herein include a heart valve replacement system that may be delivered to the targeted heart valve site via a delivery catheter. In some embodiments, the heart valve replacement system can assemble a valve device after the valve device is delivered to the heart. In some embodiments, heart valve replacement system includes two anterior flaps that are separate but overlap each other.

A prosthetic heart valve including an annular frame and a plurality of leaflets is disclosed. The annular frame includes interconnected struts defining a plurality of rows of cells arranged between an outflow and inflow end of the frame and including an upper row of cells at the outflow end. The frame further includes a plurality of commissure windows formed between axially extending window struts of the frame, each commissure window arranged between axially extending window struts of two adjacent cells and having a commissure-receiving portion that is spaced away from an upper end of the two adjacent cells and an open end. Each leaflet includes opposing commissure tabs, each commissure tab being paired with an adjacent commissure tab of an adjacent leaflet to form a commissure, each commissure arranged within the commissure-receiving portion of a respective commissure window, the open end of the commissure window configured to receive the commissure.

An implantable prosthetic device can include a frame movable between a radially compressed and a radially expanded configuration and a sealing member. The frame can include an inflow end portion, an outflow end portion, and a plurality of struts. The sealing member can be disposed around the frame and can include a cushioning layer comprising a plurality of texturized yarns extending along the longitudinal axis of the frame, and a base layer disposed between the cushioning layer and the frame.

Disclosed in the present disclosure is a prosthetic heart valve comprising a universal core which can be universally used in different implantation positions and different application scenarios, and an adapter selected from more than one adapters which are respectively suitable for the different application scenarios. The prosthetic heart valve according to the present disclosure has better flexibility and wider application range compared with various existing prosthetic heart valves, and may save time cost and research and development cost.

A collapsible and expandable prosthetic heart valve stent is provided and comprising an outer section, a valve support defining a flow channel therethrough, a transition section configured to smoothly transition the outer section to the valve support. The valve support is disposed within an interior defined by the outer section, with the inflow end of the valve support disposed inside the outer section's interior. In some cases, the outflow end of the valve support is at least partially defined by the transition section. The prosthetic leaflets are disposed on the inner surface of the valve support's flow channel and are located at or above the annulus of the heart chamber. A prolapse prevention system is attached to the stent to mitigate native valve leaflet prolapse.

The embodiments of the present disclosure provide an interventional valve stent and an aortic valve. The interventional valve stent may include a valve stent defining a frame lumen. The valve stent may include straight rods connecting an upstream port and a downstream port, and oblique rods connected between the straight rods. An upstream section, a midstream section, and a downstream section may be sequentially formed along a direction from the upstream port to the downstream port. When the valve stent expands from a compressed state to an expanded state, an expansion strain provided by the oblique rods located in the midstream section to a circumferential direction of the valve stent may be greater than an expansion strain provided by the oblique rods located in the upstream section and/or the downstream section to the circumferential direction of the valve stent to compensate for a rate difference between a rate of circumferential expansion of the midstream section and a rate of circumferential expansion of the upstream section and/or a rate of circumferential expansion of the downstream section.

A medical implant, such as a transcatheter deliverable endoprosthesis or a prosthetic heart valve including a stent-structure, one or more skirts and optionally a valve assembly. One or more skirts and/or the one or more leaflets include one or more laser markings that partially or fully penetrate a thickness of the one or more skirts and/or the one or more leaflets. The laser marks are preferably sufficiently big to be optically visible at the surface of the outer skirt by an operator during a sewing process. Each laser marking may be used for suturing, wherein the reduced material thickness eases the suturing/sewing process without compromising the structural integrity of the material of the outer skirt (e.g. a biological tissue

Apparatuses, systems, and methods for crimping prosthetic implants onto a delivery apparatus are disclosed. In some examples, a support body for a prosthetic heart valve can comprise a first portion comprising an alignment device configured to couple with a crimping device, and a second portion comprising a support surface that tapers from a wider end disposed adjacent the first portion to a narrower end, where the support surface is configured to receive the prosthetic heart valve thereon and hold one or more leaflets of the prosthetic heart valve in an open position. The support body can further comprise a central channel extending through the first portion and the second portion, the central channel configured to receive a delivery apparatus for the prosthetic heart valve therethrough.