The present disclosure relates generally to oral compositions and methods for freshening breath and oral cleansing, and more particularly, to oral compositions comprising a combination of an extract of magnolia and a hydrocarbon. The oral compositions are useful for improving oral health, including freshening breath and reducing the adherence of plaque to teeth.

The invention relates to a composition of oil-in-water emulsion type comprising: —at least one polyol in a content ranging from 7% to 25% by weight relative to the total weight of the composition; —water in a content ranging from 60% to 90% by weight relative to the total weight of the composition; —at least two nonionic surfactants that are different from each other, chosen from a nonionic surfactant of ester type comprising a mixture of at least one unsaturated ester and of at least one diester of polyglycerol and a nonionic surfactant which is a fatty alcohol with a saturated, linear carbon-based chain containing from 14 to 26 carbon atoms; —at least one wax; —and the mass ratio [total amount of said nonionic surfactant(s) of ester type]/[total amount of said wax] ranges from 0.8 to 2, preferably from 1 to 1.5.

The invention relates to a composition of oil-in-water emulsion type comprising: —at least one polyol in a content ranging from 7% to 25% by weight relative to the total weight of the composition; —water in a content ranging from 60% to 90% by weight relative to the total weight of the composition; —at least two nonionic surfactants that are different from each other, chosen from a nonionic surfactant of ester type comprising a mixture of at least one unsaturated ester and of at least one diester of polyglycerol and a nonionic surfactant which is a fatty alcohol with a saturated, linear carbon-based chain containing from 14 to 26 carbon atoms; —at least one wax; —and the mass ratio [total amount of said nonionic surfactant(s) of ester type]/[total amount of said wax] ranges from 0.8 to 2, preferably from 1 to 1.5.

The invention provides a topical o/w emulsion which moisturizes, and protects, repairs or restores the skin lipid barrier of a mammal. The topical o/w emulsion composition comprises: a) a discontinuous oil phase; b) a continuous aqueous phase comprising water; c) a thickening agent; d) at least one lamellar membrane structure comprising (i) a phospholipid, (ii) a fatty alcohol, and (iii) a fatty acid; e) a pharmaceutically acceptable active agent; and f) optionally a dermatologically acceptable excipient. In one embodiment, the composition, in use, has a water vapor transmission rate of less than or about 75 g.Math.m.sup.−2.Math.hr.sup.−1 measured in vitro using the modWVTR test methodology.

Compositions comprising select meroterpenes and a linoleic component and the use thereof in regulating the endocannabinoid system (ECS), especially in controlling and/or reducing the levels of cortisol: thereby having a stress reducing or inhibition effect.

Embodiments described herein relate generally to apparatus, methods and systems for low energy processing of consumer personal hygiene products (PHPs) and formulations of the same. In some embodiments, a method of manufacturing a consumer PHP comprises combining a first material and second material at room temperature to form a first mixture, mixing the first mixture at room temperature, adding a third material at room temperature to form a second mixture; mixing the second mixture at room temperature, adding a fourth material at room temperature to form a third mixture; and mixing the third mixture at room temperature. In some embodiments, the third material and the fourth material can be mixed to form the second mixture and the first mixture and second mixture can be combined to form the third mixture. In some embodiments, the mixing can be accomplished using a propeller mixer. In some embodiments, the propeller mixer can be rotated at a speed of greater than about 200 rpm during at least one of the mixing steps. In some embodiments, the pH of the third mixture can be adjusted to between about 4.5 and about 6.5 using an acidifier. In some embodiments, the viscosity of the third mixture can be adjusted to between about 100 cP and about 25,000 cP using a thickener.

The present application is related to cancer immunotherapy, e.g. stimulation of T cell mediated anti-tumor therapy. Accordingly, described herein are methods of inducing or enhancing an adaptive immune response to a cancer in a subject and methods of treating cancer in a subject. In some embodiments, the methods hyperactivate dendritic cells (DCs), which induce T helper type I (TH1) and cytotoxic T lymphocyte (CTL) responses in the absence of TH2 immunity.

The present invention relates to cosmetic formulations with a high moisturizing power comprising, as active principle, ucuuba (Virola surinamensis) butter comprising myristic acid in high concentration, more particularly in a concentration equal to or greater than 70% of the constitution of said butter. Additionally, the invention relates to products comprising such cosmetic formulations, as well as to the use of ucuuba butter for the preparation of a differentiated cosmetic product with high skin moisturizing power, as will be demonstrated in the present patent application. The invention further discloses a cosmetic kit comprising the formulation disclosed with a suitable applicator and instructions for use.

A biphasic topical product comprising a hydrophilic phase and a lipophilic phase floating on said hydrophilic phase. A method for preparing biphasic topical products.

The production of a cosmetic cake (8) is described, consisting of a base supporting and anchoring layer (6) and an overlapping cosmetic product layer (4), wherein said base layer (6) is formed using a dried and solidified aqueous mixture of only natural non-synthetic ingredients.