A pilling-resistant cosmetic composition is in the form of an oil in water emulsion that includes a water phase and an oily phase, and includes at least one cosmetically acceptable polymeric thickener selected from the group consisting of crosspolymers, gums, taurate based polymers, carbomers, polyacrylates, and combinations thereof, at least one ethoxylated agent in liquid form at ambient temperature in a range from about 20° C. to about 28° C. and has an HLB from about 8.5 to about 16; and at least one oil. The pilling-resistant cosmetic composition resists pilling when applied by rubbing or smoothing on a keratinous substrate.

A hair care composition is disclosed comprising a polyhydroxy fatty acid amide surfactant of general formula (I) wherein R.sup.1 is a C.sub.1-C.sub.4 alkyl groups or hydroxy-substituted C.sub.1-C.sub.4 alkyl groups; R.sup.2CO is a linear or branched, saturated or unsaturated C.sub.12-C.sub.18 acyl group, a silicone compound, and from 0.01 to 10% by weight of an anti-dandruff agent selected from piroctone olamine, azole based anti-fungal agents and mixtures thereof.

A hair care composition is disclosed comprising a polyhydroxy fatty acid amide surfactant of general formula (I) wherein R.sup.1 is a C.sub.1-C.sub.4 alkyl groups or hydroxy-substituted C.sub.1-C.sub.4 alkyl groups; R.sup.2CO is a linear or branched, saturated or unsaturated C.sub.12-C.sub.18 acyl group, a silicone compound, and from 0.01 to 10% by weight of an anti-dandruff agent selected from piroctone olamine, azole based anti-fungal agents and mixtures thereof.

The present invention relates to an isotropic concentrate composition that is easy to hydrate and transform into an end use wash composition. The end use wash composition resulting from the concentrate composition is suitable for topical application and for hand washing. The concentrate comprises fragrance oil and emulsifier at levels that unexpectedly result in a concentrate composition and end use composition that are free of ingredient precipitation that interferes with the appearance and usage of the compositions.

The object of the present disclosure is a process for decolorizing keratinous material which has been colored by the application of at least one pigment, wherein a decolorizing agent which is (a) at least one salt of a monovalent or divalent cation, and (b) has a pH value of 1.0 to 4.7,
is applied to the dyed keratin material and rinsed off again after a contact time.

The object of the present disclosure is a process for decolorizing keratinous material which has been colored by the application of at least one pigment, wherein a decolorizing agent which is (a) at least one salt of a monovalent or divalent cation, and (b) has a pH value of 1.0 to 4.7,
is applied to the dyed keratin material and rinsed off again after a contact time.

The present invention relates to a novel compound, which enables additional hydrogen bonding with amino acids at specific positions of histone acetyltransferase (HAT) p300, through structure analysis of HAT p300. The novel compound of the present invention has a remarkably excellent effect of inhibiting HAT p300 activity and thus can be very effectively used in the prevention, alleviation, or treatment of fibrosis, which is a disease associated with activation of HAT p300.

The present disclosure relates to compositions for altering the tone or color of the hair comprising at least one amino acid, at least one carboxylic acid, monoethanolamine, at least one oxidation base chosen from toluene-2,5-diamine, acid salts thereof, or solvates thereof, and a coupler system comprising one or more couplers chosen from 2,4-diaminophenoxyethanol, meta-aminophenol, derivatives thereof, addition salts thereof, solvates thereof, solvates of salts thereof, or mixtures thereof. The disclosure also relates to methods of using the compositions and kits comprising the compositions.

A composition and method are provided. The composition may be a cleansing and conditioning composition for an animal. The composition may include, a solvent, a thickening agent, a conditioning agent comprising a rice protein, and a botanical agent. The composition may be free of a lathering agent and suitable for use in cleansing and conditioning an animal.

Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.