A61K8/42

HYALURONIC ACID-BASED GELS INCLUDING LIDOCAINE
20180000992 · 2018-01-04 ·

Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.

SAFE AND STABLE ANTISEPTIC SOLUTION COMPRISING CHLORHEXIDINE
20180000733 · 2018-01-04 · ·

A stable and safe skin antiseptic solution comprises chlorhexidine, pharmaceutically acceptable salts of chlorhexidine (e.g. chlorhexidine digluconate), or a mixture thereof, dimethyl lauramide/myristamide, and water. Said solution is essentially free of coconut oil diethanolamine concentrate (“cocamide DEA”), a known carcinogen. The active antiseptic ingredient, chlorhexidine (or its salts), is a di(4-chlorophenyldiguanido) compound. The functions of dimethyl lauramide/myristamide in said solution include, but not limited to, an aesthetics enhancer, a foam stabilizer, a solubilizer, and a fragrance. Said solution is specifically formulated to be safe with a reduced risk of carcinogenicity, and be capable of producing a stable and long lasting foam. The active antiseptic agent is evenly distributed in said solution and in said foam, respectively.

Conditioner Composition Comprising a Chelant

Described herein is a hair conditioner composition and methods of using the same, the hair conditioner composition including an effective chelant. The hair conditioner composition further includes one or more high melting point fatty compounds and a cationic surfactant.

Conditioner Composition Comprising a Chelant

Described herein is a hair conditioner composition and methods of using the same, the hair conditioner composition including an effective chelant. The hair conditioner composition further includes one or more high melting point fatty compounds and a cationic surfactant.

Hygiene Product Pod and Methods of Using Same

Disclosed herein are hygiene product pods and a method of using the hygiene product pods. A hygiene product pod can include a water-soluble envelope and a hygiene product sealed in the water-soluble envelope. A hygiene product as described herein can comprise a non-aqueous carrier. A non-aqueous carrier as described herein can comprise a polyol solvent and a polyglyceryl fatty acid ester (PGEs) chassis.

Hygiene Product Pod and Methods of Using Same

Disclosed herein are hygiene product pods and a method of using the hygiene product pods. A hygiene product pod can include a water-soluble envelope and a hygiene product sealed in the water-soluble envelope. A hygiene product as described herein can comprise a non-aqueous carrier. A non-aqueous carrier as described herein can comprise a polyol solvent and a polyglyceryl fatty acid ester (PGEs) chassis.

ORAL GEL COMPOSITIONS

Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of herbal oils and extracts comprising (a) clove oil and/or eugenol (e.g., clove leaf oil and/or clove bud oil), (b) a cooling agent (e.g., menthol), (c) camphor, (d) an antimicrobial agent, e.g., turmeric and/or curcumin extract (e.g., turmeric, white turmeric (e.g., white curcumin) and (e) licorice; in an orally acceptable gel base, the gel base comprising one or more nonionic surfactants, the formulation providing a sustained release of the mixture of herbal oils and extracts following application to a tooth or gums; together with methods of making and using the same.

Dispersion of fine lipid particle dispersion
11564871 · 2023-01-31 · ·

To provide a composition in which fine particles of solid lipid such as ceramides are emulsified and dispersed in a stable manner without being crystalized. A dispersion of fine lipid particles containing the following components (A) to (E), wherein the dispersion has a pH of 3.5 or more and 8.0 or less and the fine lipid particles have a heat of fusion of 0.30 J/g or less in a temperature range of 45° C. or more and 80° C. or less and an average particle size of less than 200 nm. (A) one or more selected from the group consisting of a sterol and a derivative thereof, (B) a lipid other than the component (A), the lipid being solid or semi-solid at 25° C., (C) an anionic surfactant, (D) a water-soluble solvent and (E) water.

Dispersion of fine lipid particle dispersion
11564871 · 2023-01-31 · ·

To provide a composition in which fine particles of solid lipid such as ceramides are emulsified and dispersed in a stable manner without being crystalized. A dispersion of fine lipid particles containing the following components (A) to (E), wherein the dispersion has a pH of 3.5 or more and 8.0 or less and the fine lipid particles have a heat of fusion of 0.30 J/g or less in a temperature range of 45° C. or more and 80° C. or less and an average particle size of less than 200 nm. (A) one or more selected from the group consisting of a sterol and a derivative thereof, (B) a lipid other than the component (A), the lipid being solid or semi-solid at 25° C., (C) an anionic surfactant, (D) a water-soluble solvent and (E) water.

OIL-IN-WATER EMULSIFIED COSMETIC
20230021975 · 2023-01-26 ·

The invention provides an oil-in-water emulsified cosmetic containing (a) an aqueous medium, (b) two or more higher fatty acids of 12 to 24 carbon atoms and alkali metal salts thereof, (c) at least one compound selected from the group consisting of monoalkyl glyceryl ethers having an alkyl group of 12 to 24 carbon atoms and monoalkenyl glyceryl ethers having an alkenyl group of 12 to 24 carbon atoms, (d) a thickener comprising (d-1) a polysaccharide derived from a microorganism and (d-2) a (meth)acrylic-based polymer selected from the group consisting of a poly(meth)acrylic acid salt and a polymer including at least one selected from the group consisting of a (meth)acrylic acid ester, a (meth)acryloylalkyltaurine and a salt thereof as a structural unit, and (e) a nonionic surfactant.