A method of improving the appearance of periorbital dyschromia by identifying a target portion of skin in the periorbital region of a person that exhibits periorbital dyschromia and applying a personal care composition to the target portion of skin during a treatment period. The personal care composition includes an effective amount of Type I active, an effective amount of a Type II active, and a dermatologically acceptable carrier. The treatment period is of sufficient length for at least one of the actives to improve the appearance of the periorbital dyschromia.

Hair bleaching compositions, methods for using hair bleaching compositions, and methods for preparing hair bleaching compositions are provided herein. The hair bleaching compositions comprise at least one gallic acid derivative, at least one amino acid and/or at least one amino acid derivative, at least one oxidizing agent, and optionally, at least one hair care agent and/or hair treatment agent.

The present invention refers to methods and compositions to prevent viral entry into cells expressing the CD169/sialoadhesin surface receptor by inhibiting the coupling of the sialyllactose molecule contained in the viral membrane gangliosides to the CD 169/sialoadhesin receptor. The invention also pertains to vaccine compositions based on dendritic cells loaded with an antigen of interest whereby the vaccine is provided together with a composition capable of preventing viral entry into cells expressing the CD169/sialoadhesin. Moreover, the invention relates to diagnostic and therapeutic compositions that can be specifically delivered to enveloped virions wherein the diagnostic/therapeutic agent is coupled to CD169/sialoadhesin.

Pharmaceutical compositions comprising a first anti-acne compound, a second anti-acne compound, and an anti-photoaging compound are described. Methods for the treatment of acne and photoaging using the compositions are also described.

A system for producing a customized skin care product in less than five minutes includes active ingredient premixes, premix dispensers respectively operable to dispense a predefined quantity of the active ingredient premixes by a single dispenser operation, skin care product bases, product base dispensers respectively operable to dispense a predefined quantity of the skin care product bases by a single dispenser operation, and instructions executable by a processor to receive data indicative of a customer's skin condition and generate a recipe for producing a customized skin care product containing specified percentages by weight of two or more active ingredients suited for the customer's skin condition. The recipe defines a number of operations of one or more of the premix dispensers and one of the product base dispensers. The system further includes a mixing machine operable to mix the contents of a closed container filled in accordance with the recipe.

The present specification discloses a composition for external application to skin, containing a tea plant root extract as an active ingredient, for treatment of skin damage caused by fine dust, whereby the expression level of one or more selected from a group consisting of IL-36G (NM_019618), S100A7 (NM_002963), S100A8 (NM_002964) and XDH (NM_000379), which are genes in skin cells the expression level of which is affected by fine dust, is regulated to a normal level.

A moldable gel cleanser comprising a carrageenan, a source of potassium and a glycol is disclosed.

A new stevia variety is characterized by remarkably high levels of Rebaudioside C (RC), and developed by the use of non-GMO selective breeding technologies and wherein such variety is uniquely identified by RAPD gene analysis, and comprises from about 3-8% by weight RC in the leaf (leaf content) and from about 10-13% total steviol glycosides content (TSG) in in leaf (leaf content), both of which are exceptionally high.

Succinic acid esters of resveratrol and topical compositions containing the esters.

The present invention relates to a composition, in particular cosmetic composition, comprising: (a) at least one synthetic phyllosilicate having the molecular formula Mg.sub.3Si.sub.4O.sub.10(OH).sub.2; and (b) at least one polyol and/or polyol derivative, and/or at least one UV filter. The present invention further relates to the use of a synthetic phyllosilicate having the molecular formula Mg.sub.3Si.sub.4O.sub.10(OH).sub.2 for reducing the tackiness and/or for increasing the hydrating effect of said composition, the cosmetic use of said composition for topical skin and/or nail care, a cosmetic treatment method comprising topical application of said composition to the skin and/or the nails, a cosmetic method for limiting the darkening of the skin and/or the nails and/or for improving the colour and/or the homogeneity of the complexion, and a cosmetic method for preventing and/or treating signs of ageing of the skin and/or the nails comprising applying said composition to the surface of the skin and/or the nails.